Wednesday, July 8, 2026

Drug profile · INN

lomustine

lomustine (GLEOSTINE) is a dna inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 7
News articles 0
Drug details — lomustine
US status
approved
Class
Route
ORAL
Patents
0
Programs
7
Data quality
0.84

Quick answer

lomustine (GLEOSTINE) is a dna inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN lomustine
Brand GLEOSTINE
Mechanism DNA inhibitor
Target DNA
Route ORAL
Formulation CAPSULE

Mechanism of action

DNA inhibitor

Primary target: DNA

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. 131I-TLX-101-003 Phase 3 · Anaxis Pharma · Glioblastoma
  2. LOMUSTINE Phase 3 · Ningbo Cancer Hospital · Glioblastoma
  3. TLX-101-Tx + Lomustine Phase 3 · Telix Innovations · Neoplastic Disease
  4. lomustine Phase 3 · United Therapeutics Europe · Brain and Central Nervous System Tumors
  5. 1634 Phase 2 · Ningbo Cancer Hospital · Newly Diagnosed Medulloblastoma
  6. APHP200080 Phase 2 · PARItec · Newly diagnosed Glioblastoma (IDH wild-type) patients at ini
  7. Lomustine "medac" 40 mg, Fibromun Phase 2 · Philogen · Glioblastoma

Related & competitor drugs

  1. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  2. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  3. azacitidine Antineoplastic and immunomodulating agents (L01)
  4. bleomycin sulfate DNA inhibitor
  5. busulfan Antineoplastic and immunomodulating agents (L01)
  6. capecitabine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is lomustine?

lomustine (GLEOSTINE) is a dna inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for lomustine?

GLEOSTINE is a marketed brand name for lomustine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of lomustine?

lomustine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.