Wednesday, July 8, 2026

Drug profile · INN

lenvatinib mesylate

lenvatinib mesylate (LENVIMA) is a vascular endothelial growth factor receptor inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 51
News articles 0
Drug details — lenvatinib mesylate
US status
approved
Class
Route
ORAL
Patents
0
Programs
51
Data quality
0.84

Quick answer

lenvatinib mesylate (LENVIMA) is a vascular endothelial growth factor receptor inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN lenvatinib mesylate
Brand LENVIMA
Mechanism Vascular endothelial growth factor receptor inhibitor
Target Vascular endothelial growth factor receptor
Route ORAL
Formulation CAPSULE

Mechanism of action

Vascular endothelial growth factor receptor inhibitor

Primary target: Vascular endothelial growth factor receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. 2023/3764 Phase 3 · George Institute for · Metastatic renal cell carcinoma (mRCC)
  2. CA209-9DW Phase 3 · Bristol-Myers Squibb Australia · Hepatocellular Carcinoma, Hepatocellular Carcinoma, Hepatoce
  3. CS1003-305 Phase 3 · Anaxis Pharma · Unresectable advanced hepatocellular carcinoma
  4. D910VC00001 Phase 3 · AstraZeneca · Locoregional Hepatocellular Carcinoma (HCC)
  5. Lenvatinib Phase 3 · Merck KGaA, Darmstadt · Carcinoma, Hepatocellular
  6. Lenvatinib Phase 3 · First People's Hospital · Hepatocellular Carcinoma
  7. MK-6482-011 Phase 3 · MSD Merck Sharp · Advanced RCC with clear cell component
  8. MK-6482-043 Phase 3 · MSD Merck Sharp · Renal Cell Carcinoma, hepatocellular carcinoma, nonMSI-H/dMM

Related & competitor drugs

  1. axitinib Antineoplastic and immunomodulating agents (L01)
  2. fruquintinib Antineoplastic and immunomodulating agents (L01)
  3. ramucirumab Antineoplastic and immunomodulating agents (L01)
  4. tivozanib Vascular endothelial growth factor receptor inhibitor
  5. lenvatinib mesilate Vascular endothelial growth factor receptor inhibitor

Frequently asked questions

What is lenvatinib mesylate?

lenvatinib mesylate (LENVIMA) is a vascular endothelial growth factor receptor inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for lenvatinib mesylate?

LENVIMA is a marketed brand name for lenvatinib mesylate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of lenvatinib mesylate?

lenvatinib mesylate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.