Wednesday, July 8, 2026

Drug profile · INN

ifosfamide

ifosfamide (HOLOXAN) is a dna inhibitor. Associated with BAXTER HEALTHCARE PTY LTD. Route of administration: injection. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 1
Pipeline programs 18
News articles 0
Drug details — ifosfamide
US status
approved
Class
Route
INJECTION
Patents
1
Programs
18
Data quality
0.89

Quick answer

ifosfamide (HOLOXAN) is a dna inhibitor. Associated with BAXTER HEALTHCARE PTY LTD. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN ifosfamide
Brand HOLOXAN
Mechanism DNA inhibitor
Target DNA
Route INJECTION
Formulation INJECTABLE

Mechanism of action

DNA inhibitor

Primary target: DNA

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. 1407-GUCG Phase 3 · Ningbo Cancer Hospital · Progressive or recurrent germ cell tumor (measurable or non-
  2. CCTL019H2301 Phase 3 · Novartis India · Adult patients with relapsed or refractory aggressive B-cell
  3. HOVON 127 BL Phase 3 · Createrna Science and · Burkitt lymphoma
  4. IB2017-04 Phase 3 · George Institute for · Resectable, non-metastatic soft-tissue sarcoma (STS)
  5. doxorubicin in combination with palifosfamide-tris Phase 3 · Alaunos Therapeutics · Soft Tissue Sarcoma
  6. CO43810 Phase 2 · HOFFMANN-LA ROCHE · CD20 positive B-Cell Non-Hodgkin Lymphoma (NHL)
  7. GCT3013-02 Phase 2 · Genmab · Lymphoma of B-cell origin
  8. IB 2021-01 Phase 2 · George Institute for · Adult patients with treatment-naïve surgically non-metastati

Related & competitor drugs

  1. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  2. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  3. azacitidine Antineoplastic and immunomodulating agents (L01)
  4. bleomycin sulfate DNA inhibitor
  5. busulfan Antineoplastic and immunomodulating agents (L01)
  6. capecitabine Antineoplastic and immunomodulating agents (L01)
  1. US 6037337

    Use of the enantiomers of ifosfamide in antitumor therapy for reducing side effects

    Expires Mon Mar 09 2020 00:00:00 GMT+0000 (Coordinated Universal Time)

    expired

Frequently asked questions

What is ifosfamide?

ifosfamide (HOLOXAN) is a dna inhibitor. Associated with BAXTER HEALTHCARE PTY LTD. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for ifosfamide?

HOLOXAN is a marketed brand name for ifosfamide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ifosfamide?

ifosfamide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.