Wednesday, July 8, 2026

Drug profile · INN

hydrochlorothiazide

hydrochlorothiazide (DITHIAZIDE) is a thiazide-sensitive sodium-chloride cotransporter inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved TGA: approved
US status approved
Patents linked 9
Pipeline programs 36
News articles 0
Drug details — hydrochlorothiazide
US status
approved
Class
Route
ORAL
Patents
9
Programs
36
Data quality
0.89

Quick answer

hydrochlorothiazide (DITHIAZIDE) is a thiazide-sensitive sodium-chloride cotransporter inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN hydrochlorothiazide
Brand DITHIAZIDE
Mechanism Thiazide-sensitive sodium-chloride cotransporter inhibitor
Target Solute carrier family 12 member 3
Route ORAL
Formulation CAPSULE

Mechanism of action

Thiazide-sensitive sodium-chloride cotransporter inhibitor

Primary target: Solute carrier family 12 member 3

Approval history

Authority Status Date
FDA approved
TGA approved

Pipeline programs

  1. Losartan Phase 3 · BRIGHT MINDS BIOSCIENCES · Glomerulonephritis, IGA
  2. NP101 Sumatriptan Iontophoretic Transdermal Patch Phase 3 · Teva Pharma · Migraine Disorders
  3. PI23/00797 Phase 3 · George Institute for · Acute Heart Failure
  4. Propranolol Phase 3 · United Therapeutics Europe · Burn
  5. olmesartan alone or in combination with hydrochlorothiazide Phase 3 · Pfizer · Essential Hypertension
  6. LOSARTAN Phase 2 · Istituto Gentili Italia · Osteogenesis Imperfecta
  7. Losartan Phase 2 · United Therapeutics Europe · Hip Osteoarthritis
  8. Losartan Potassium Phase 2 · Ultragenyx UK · Eosinophilic Esophagitis

Related & competitor drugs

  1. chlorothiazide sodium Thiazide-sensitive sodium-chloride cotransporter inhibitor
  2. chlorthalidone Thiazide-sensitive sodium-chloride cotransporter inhibitor
  3. indapamide Thiazide-sensitive sodium-chloride cotransporter inhibitor
  4. bendroflumethiazide Thiazide-sensitive sodium-chloride cotransporter inhibitor
  5. benzthiazide Thiazide-sensitive sodium-chloride cotransporter inhibitor
  6. chlorothiazide Thiazide-sensitive sodium-chloride cotransporter inhibitor
  1. US 10722581

    Phonophoretic cannabidiol composition and transdermal delivery system

    Expires Mon Jul 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10398776

    Phonophoretic cannabidiol composition and transdermal delivery system

    Expires Mon Aug 29 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 9592291

    Methods for iontophoretically treating nausea and migraine

    Expires Mon Mar 09 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 9427578

    Pharmacokinetics of iontophoretic sumatriptan administration

    Expires Mon Aug 25 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8530621

    Combined preparation of a thiazide diuretic and a loop diuretic

    Expires Mon Sep 05 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8067636

    Dihydrazide compounds, preparation and uses thereof

    Expires Mon Nov 24 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7906513

    Hydrazide-containing hepatitis C serine protease inhibitors

    Expires Mon Mar 10 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7888332

    Hydrazide-containing CFTR inhibitor compounds and uses thereof

    Expires Mon Feb 10 2031 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7414037

    Hydrazide-containing CFTR inhibitor compounds and uses thereof

    Expires Mon Aug 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is hydrochlorothiazide?

hydrochlorothiazide (DITHIAZIDE) is a thiazide-sensitive sodium-chloride cotransporter inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for hydrochlorothiazide?

DITHIAZIDE is a marketed brand name for hydrochlorothiazide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of hydrochlorothiazide?

hydrochlorothiazide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.