Wednesday, July 8, 2026

Drug profile · INN

chlorothiazide

chlorothiazide (DIUPRES-500) is a thiazide-sensitive sodium-chloride cotransporter inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 11
News articles 0
Drug details — chlorothiazide
US status
approved
Class
Route
ORAL
Patents
0
Programs
11
Data quality
0.84

Quick answer

chlorothiazide (DIUPRES-500) is a thiazide-sensitive sodium-chloride cotransporter inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN chlorothiazide
Brand DIUPRES-500
Mechanism Thiazide-sensitive sodium-chloride cotransporter inhibitor
Target Solute carrier family 12 member 3
Route ORAL
Formulation SUSPENSION

Mechanism of action

Thiazide-sensitive sodium-chloride cotransporter inhibitor

Primary target: Solute carrier family 12 member 3

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. PI23/00797 Phase 3 · George Institute for · Acute Heart Failure
  2. olmesartan alone or in combination with hydrochlorothiazide Phase 3 · Pfizer · Essential Hypertension
  3. Losartan potassium/Hydrochlorothiazide Phase 1 · Teva Pharma · Healthy
  4. Moexipril HCl/hydrochlorothiazide 15/25 mg tablets Phase 1 · Teva Pharma · Healthy
  5. Ramipril/Hydrochlorothiazide tablet 10 mg/25 mg Phase 1 · LIGAND PHARMACEUTICALS · Bioequivalence
  6. Randomized for not applicable (submitted trial is bioavailability) Phase 1 · Anaxis Pharma · not applicable (submitted trial is bioavailability)
  7. Candesartan and Hydrochlorothiazide Approved · Takeda · Obesity
  8. Candesartan cilexetil and hydrochlorothiazide Approved · Takeda · Hypertension

Related & competitor drugs

  1. chlorothiazide sodium Thiazide-sensitive sodium-chloride cotransporter inhibitor
  2. chlorthalidone Thiazide-sensitive sodium-chloride cotransporter inhibitor
  3. hydrochlorothiazide Thiazide-sensitive sodium-chloride cotransporter inhibitor
  4. indapamide Thiazide-sensitive sodium-chloride cotransporter inhibitor
  5. bendroflumethiazide Thiazide-sensitive sodium-chloride cotransporter inhibitor
  6. benzthiazide Thiazide-sensitive sodium-chloride cotransporter inhibitor

Frequently asked questions

What is chlorothiazide?

chlorothiazide (DIUPRES-500) is a thiazide-sensitive sodium-chloride cotransporter inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for chlorothiazide?

DIUPRES-500 is a marketed brand name for chlorothiazide. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of chlorothiazide?

chlorothiazide has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.