Wednesday, July 8, 2026

Drug profile · INN

glasdegib maleate

glasdegib maleate (DAURISMO) is a smoothened homolog antagonist. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 1
News articles 0
Drug details — glasdegib maleate
US status
approved
Class
Route
ORAL
Patents
0
Programs
1
Data quality
0.84

Quick answer

glasdegib maleate (DAURISMO) is a smoothened homolog antagonist. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN glasdegib maleate
Brand DAURISMO
Mechanism Smoothened homolog antagonist
Target Protein smoothened
Route ORAL
Formulation TABLET

Mechanism of action

Smoothened homolog antagonist

Primary target: Protein smoothened

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Glasdegib Phase 2 · Jazz Pharmaceuticals Ireland · Acute Myelogenous Leukemia (AML) Due to Therapy

Related & competitor drugs

  1. sonidegib phosphate Smoothened homolog inhibitor
  2. vismodegib Antineoplastic and immunomodulating agents (L01)
  3. glasdegib Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is glasdegib maleate?

glasdegib maleate (DAURISMO) is a smoothened homolog antagonist. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for glasdegib maleate?

DAURISMO is a marketed brand name for glasdegib maleate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of glasdegib maleate?

glasdegib maleate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.