Wednesday, July 8, 2026

Drug profile · INN

vismodegib

vismodegib (ERIVEDGE) is a smoothened homolog inhibitor. Associated with Hoffmann-La Roche. Route of administration: oral. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L01) L01XX43
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — vismodegib
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
ORAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

vismodegib (ERIVEDGE) is a smoothened homolog inhibitor. Associated with Hoffmann-La Roche. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN vismodegib
Brand ERIVEDGE
Mechanism Smoothened homolog inhibitor
Target Protein smoothened
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route ORAL
Formulation CAPSULE
ATC code L01XX43

Mechanism of action

Smoothened homolog inhibitor

Primary target: Protein smoothened

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is vismodegib?

vismodegib (ERIVEDGE) is a smoothened homolog inhibitor. Associated with Hoffmann-La Roche. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for vismodegib?

ERIVEDGE is a marketed brand name for vismodegib. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of vismodegib?

vismodegib has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.