Wednesday, July 8, 2026

Drug profile · INN

gepirone hydrochloride

gepirone hydrochloride (EXXUA) is a serotonin 1a (5-ht1a) receptor agonist. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 1
News articles 0
Drug details — gepirone hydrochloride
US status
approved
Class
Route
ORAL
Patents
0
Programs
1
Data quality
0.84

Quick answer

gepirone hydrochloride (EXXUA) is a serotonin 1a (5-ht1a) receptor agonist. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN gepirone hydrochloride
Brand EXXUA
Mechanism Serotonin 1a (5-HT1a) receptor agonist
Target 5-hydroxytryptamine receptor 1A
Route ORAL
Formulation TABLET, EXTENDED RELEASE

Mechanism of action

Serotonin 1a (5-HT1a) receptor agonist

Primary target: 5-hydroxytryptamine receptor 1A

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Gepirone Phase 2 · BRIGHT MINDS BIOSCIENCES · Cocaine-Related Disorders

Related & competitor drugs

  1. buspirone hydrochloride Serotonin 1a (5-HT1a) receptor partial agonist
  2. vilazodone hydrochloride Serotonin transporter inhibitor
  3. vortioxetine hydrobromide Serotonin transporter inhibitor
  4. methysergide maleate Serotonin 1a (5-HT1a) receptor partial agonist

Frequently asked questions

What is gepirone hydrochloride?

gepirone hydrochloride (EXXUA) is a serotonin 1a (5-ht1a) receptor agonist. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for gepirone hydrochloride?

EXXUA is a marketed brand name for gepirone hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of gepirone hydrochloride?

gepirone hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.