Wednesday, July 8, 2026

Drug profile · INN

buspirone hydrochloride

buspirone hydrochloride (BUSPIRONE HYDROCHLORIDE) is a serotonin 1a (5-ht1a) receptor partial agonist. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — buspirone hydrochloride
US status
approved
Class
Route
ORAL
Patents
0
Programs
5
Data quality
0.89

Quick answer

buspirone hydrochloride (BUSPIRONE HYDROCHLORIDE) is a serotonin 1a (5-ht1a) receptor partial agonist. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN buspirone hydrochloride
Brand BUSPIRONE HYDROCHLORIDE
Mechanism Serotonin 1a (5-HT1a) receptor partial agonist
Target 5-hydroxytryptamine receptor 1A
Route ORAL
Formulation CAPSULE

Mechanism of action

Serotonin 1a (5-HT1a) receptor partial agonist

Primary target: 5-hydroxytryptamine receptor 1A

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. Buspirone Phase 2 · BRIGHT MINDS BIOSCIENCES · Cocaine Dependence
  2. BUSPAR® 30 mg Tablet Phase 1 · Teva Pharma · Healthy
  3. Buspirone Approved · BRIGHT MINDS BIOSCIENCES · Marijuana Dependence
  4. Buspirone Unknown · BRIGHT MINDS BIOSCIENCES · Cocaine Use Disorders
  5. Buspirone Unknown · First People's Hospital · Anxiety Disorders

Related & competitor drugs

  1. vilazodone hydrochloride Serotonin transporter inhibitor
  2. vortioxetine hydrobromide Serotonin transporter inhibitor
  3. gepirone hydrochloride Serotonin 1a (5-HT1a) receptor agonist
  4. methysergide maleate Serotonin 1a (5-HT1a) receptor partial agonist

Frequently asked questions

What is buspirone hydrochloride?

buspirone hydrochloride (BUSPIRONE HYDROCHLORIDE) is a serotonin 1a (5-ht1a) receptor partial agonist. Associated with Amneal Pharma Europe Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for buspirone hydrochloride?

BUSPIRONE HYDROCHLORIDE is a marketed brand name for buspirone hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of buspirone hydrochloride?

buspirone hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.