Saturday, July 11, 2026

Drug profile · INN

eptotermin alfa

eptotermin alfa (OSIGRAFT) is a bone morphogenetic protein receptor type-1a agonist.

EMA: withdrawn Musculo-skeletal system (M05) M05BC02
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Drug details — eptotermin alfa
Class
Musculo-skeletal system (M05)
Route
Patents
0
Programs
0
Data quality
0.83

Quick answer

eptotermin alfa (OSIGRAFT) is a bone morphogenetic protein receptor type-1a agonist.

Key facts

INN eptotermin alfa
Brand OSIGRAFT
Mechanism Bone morphogenetic protein receptor type-1A agonist
Target Activin receptor type-1
Therapeutic class Musculo-skeletal system (M05)
ATC code M05BC02

Mechanism of action

Bone morphogenetic protein receptor type-1A agonist

Primary target: Activin receptor type-1

Approval history

Authority Status Date
EMA withdrawn

Related & competitor drugs

  1. allopurinol Musculo-skeletal system (M04)
  2. colchicine Musculo-skeletal system (M04)
  3. denosumab Musculo-skeletal system (M05)
  4. eteplirsen Musculo-skeletal system (M09)
  5. febuxostat Musculo-skeletal system (M04)
  6. ibandronic acid Musculo-skeletal system (M05)

Frequently asked questions

What is eptotermin alfa?

eptotermin alfa (OSIGRAFT) is a bone morphogenetic protein receptor type-1a agonist.

What is the brand name for eptotermin alfa?

OSIGRAFT is a marketed brand name for eptotermin alfa. Check FDA Drugs@FDA for the current US label holder and prescribing information.