Wednesday, July 8, 2026

Drug profile · INN

efinaconazole

efinaconazole (CLENAFIN) is a lanosterol 14-alpha demethylase inhibitor. Associated with Teva Pharma GmbH. Route of administration: topical. Current US regulatory status: approved.

FDA: approved PMDA: approved
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Drug details — efinaconazole
US status
approved
Class
Route
TOPICAL
Patents
0
Programs
0
Data quality
0.89

Quick answer

efinaconazole (CLENAFIN) is a lanosterol 14-alpha demethylase inhibitor. Associated with Teva Pharma GmbH. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN efinaconazole
Brand CLENAFIN
Mechanism Lanosterol 14-alpha demethylase inhibitor
Target Lanosterol 14-alpha demethylase
Route TOPICAL
Formulation SOLUTION

Mechanism of action

Lanosterol 14-alpha demethylase inhibitor

Primary target: Lanosterol 14-alpha demethylase

Approval history

Authority Status Date
FDA approved
PMDA approved

Related & competitor drugs

  1. clotrimazole Cytochrome P450 51 inhibitor
  2. fluconazole Cytochrome P450 51 inhibitor
  3. itraconazole Cytochrome P450 51 inhibitor
  4. ketoconazole Antiinfectives for systemic use (J02)
  5. miconazole nitrate Cytochrome P450 51 inhibitor
  6. posaconazole Antiinfectives for systemic use (J02)

Frequently asked questions

What is efinaconazole?

efinaconazole (CLENAFIN) is a lanosterol 14-alpha demethylase inhibitor. Associated with Teva Pharma GmbH. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for efinaconazole?

CLENAFIN is a marketed brand name for efinaconazole. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of efinaconazole?

efinaconazole has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.