Wednesday, July 8, 2026

Drug profile · INN

ketoconazole

ketoconazole (KETOCONAZOLE AID-SCFM) is a cytochrome p450 51 inhibitor. Associated with S.A.. Route of administration: topical. Current US regulatory status: approved.

FDA: approved EMA: approved Antiinfectives for systemic use (J02) J02AB02
US status approved
Patents linked 11
Pipeline programs 2
News articles 0
Drug details — ketoconazole
US status
approved
Class
Antiinfectives for systemic use (J02)
Route
TOPICAL
Patents
11
Programs
2
Data quality
0.89

Quick answer

ketoconazole (KETOCONAZOLE AID-SCFM) is a cytochrome p450 51 inhibitor. Associated with S.A.. Route of administration: topical. Current US regulatory status: approved.

Key facts

INN ketoconazole
Brand KETOCONAZOLE AID-SCFM
Mechanism Cytochrome P450 51 inhibitor
Target Lanosterol 14-alpha demethylase
Therapeutic class Antiinfectives for systemic use (J02)
Route TOPICAL
Formulation SHAMPOO
ATC code J02AB02
Originator S.A.

Mechanism of action

Cytochrome P450 51 inhibitor

Primary target: Lanosterol 14-alpha demethylase

Approval history

Authority Status Date
FDA approved
EMA approved

Pipeline programs

  1. docetaxel and ketoconazole Phase 2 · Hospital Authority · Metastatic Breast Cancer
  2. NBI-98854 50 mg capsule once daily Phase 1 · NEUROCRINE BIOSCIENCES · Effect of Ketoconazole on the PK of NBI-98854 in Healthy Sub

Related & competitor drugs

  1. atazanavir sulfate Antiinfectives for systemic use (J05)
  2. clotrimazole Cytochrome P450 51 inhibitor
  3. colistimethate sodium Antiinfectives for systemic use (J01)
  4. covid-19 mrna vaccine Antiinfectives for systemic use (J07)
  5. daptomycin Antiinfectives for systemic use (J01)
  6. darunavir Antiinfectives for systemic use (J05)
  1. US 12377096

    Methods of treating disease with levoketoconazole

    Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12263227

    Optimized mRNA encoding CAS9 for use in LNPs

    Expires Mon Mar 27 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12227763

    Methods and compositions for treating cancer

    Expires Mon Feb 13 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12188060

    Messenger RNA encoding Cas9 for use in genome-editing systems

    Expires Mon Jan 02 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12016932

    Gene editing for hemophilia A with improved factor VIII expression

    Expires Mon Jun 20 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11833225

    Methods and compositions for efficient gene deletion

    Expires Mon Nov 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11827877

    Compositions and methods for genomic editing by insertion of donor polynucleotides

    Expires Mon Nov 23 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11649438

    Methods and compositions for treating cancer

    Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11529427

    Gene editing for hemophilia A with improved factor VIII expression

    Expires Mon Dec 15 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11332760

    Compositions and methods for genomic editing by insertion of donor polynucleotides

    Expires Mon May 12 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11254912

    Methods and compositions for treating cancer

    Expires Mon Feb 17 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is ketoconazole?

ketoconazole (KETOCONAZOLE AID-SCFM) is a cytochrome p450 51 inhibitor. Associated with S.A.. Route of administration: topical. Current US regulatory status: approved.

What is the brand name for ketoconazole?

KETOCONAZOLE AID-SCFM is a marketed brand name for ketoconazole. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of ketoconazole?

ketoconazole has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.