Friday, July 10, 2026

Drug profile · INN

daunorubicin

daunorubicin (VYXEOS LIPOSOMAL (PREVIOUSLY VYXEOS)) is a dna topoisomerase ii alpha inhibitor. Associated with Jazz Pharmaceuticals Ireland Limited.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01XY01
Patents linked 0
Pipeline programs 13
News articles 0
Drug details — daunorubicin
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
13
Data quality
0.89

Quick answer

daunorubicin (VYXEOS LIPOSOMAL (PREVIOUSLY VYXEOS)) is a dna topoisomerase ii alpha inhibitor. Associated with Jazz Pharmaceuticals Ireland Limited.

Key facts

INN daunorubicin
Brand VYXEOS LIPOSOMAL (PREVIOUSLY VYXEOS)
Mechanism DNA topoisomerase II alpha inhibitor
Target DNA
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XY01

Mechanism of action

DNA topoisomerase II alpha inhibitor

Primary target: DNA

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. DAUNORUBICIN for Favorable-intermediate-risk Acu… Phase 3 · Telethon Foundation · Favorable-intermediate-risk Acute Myeloid Leukemia
  2. Daunorubicin/Idarubicin Phase 3 · Chinese Academy of · AML, Adult
  3. GIMEMA AML1919 Phase 3 · Telethon Foundation · Acute Myeloid Leukemia (LMA) with FLT3 mutation
  4. IRST204.07 Phase 3 · Istituto Gentili Italia · Acute myeloid leukemia
  5. MDS0519 Phase 3 · Telethon Foundation · Higher-risk-myelodysplastic syndromes
  6. SNDX-5613-0710 Phase 3 · Syndax Pharmaceuticals · Newly Diagnosed AML with an NPM1 mutation
  7. CPKC412A2218 Phase 2 · Novartis India · untreated FLT3-mutated Acute Myeloid Leukemia
  8. Daunorubicin Phase 2 · Hospital Authority · Down Syndrome

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  3. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  4. anagrelide Antineoplastic and immunomodulating agents (L01)
  5. apremilast Antineoplastic and immunomodulating agents (L04)
  6. arsenic trioxide Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is daunorubicin?

daunorubicin (VYXEOS LIPOSOMAL (PREVIOUSLY VYXEOS)) is a dna topoisomerase ii alpha inhibitor. Associated with Jazz Pharmaceuticals Ireland Limited.

What is the brand name for daunorubicin?

VYXEOS LIPOSOMAL (PREVIOUSLY VYXEOS) is a marketed brand name for daunorubicin. Check FDA Drugs@FDA for the current US label holder and prescribing information.