Friday, July 10, 2026

Drug profile · INN

crisantaspase

crisantaspase (ENRYLAZE) is a asparagine hydrolytic enzyme. Associated with Jazz Pharmaceuticals Ireland Limited.

EMA: approved Antineoplastic and immunomodulating agents (L01) L01XX02
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — crisantaspase
Class
Antineoplastic and immunomodulating agents (L01)
Route
Patents
0
Programs
5
Data quality
0.89

Quick answer

crisantaspase (ENRYLAZE) is a asparagine hydrolytic enzyme. Associated with Jazz Pharmaceuticals Ireland Limited.

Key facts

INN crisantaspase
Brand ENRYLAZE
Mechanism Asparagine hydrolytic enzyme
Target Asparagine
Therapeutic class Antineoplastic and immunomodulating agents (L01)
ATC code L01XX02

Mechanism of action

Asparagine hydrolytic enzyme

Primary target: Asparagine

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. 20190360 Phase 3 · Amgen · Newly diagnosed Philadelphia-negative B-cell precursor Acute
  2. B1931036 Phase 2 · First Biotech (Australia) · Acute Lymphoblastic Leukemia (ALL)
  3. Erwinaze® (Asparaginase Erwinia Chrysanthemi)/Erwinase® (Crisantaspase) Phase 2 · Jazz Pharmaceuticals Ireland · Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (L
  4. pegcrisantaspase Phase 2 · Jazz Pharmaceuticals Ireland · Acute Lymphoblastic Leukemia
  5. mPEG-r-crisantaspase Phase 1 · Jazz Pharmaceuticals Ireland · Hematologic Malignancies

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. asparaginase erwinia chrysanthemi (recombinant)-rywn Asparagine hydrolytic enzyme
  6. axitinib Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is crisantaspase?

crisantaspase (ENRYLAZE) is a asparagine hydrolytic enzyme. Associated with Jazz Pharmaceuticals Ireland Limited.

What is the brand name for crisantaspase?

ENRYLAZE is a marketed brand name for crisantaspase. Check FDA Drugs@FDA for the current US label holder and prescribing information.