Wednesday, July 8, 2026

Drug profile · INN

clofarabine

clofarabine (EVOLTRA) is a dna polymerase (alpha/delta/epsilon) inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved Antineoplastic and immunomodulating agents (L01) L01BB06
US status approved
Patents linked 0
Pipeline programs 1
News articles 0
Drug details — clofarabine
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
INJECTION
Patents
0
Programs
1
Data quality
0.89

Quick answer

clofarabine (EVOLTRA) is a dna polymerase (alpha/delta/epsilon) inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN clofarabine
Brand EVOLTRA
Mechanism DNA polymerase (alpha/delta/epsilon) inhibitor
Target DNA
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route INJECTION
Formulation INJECTABLE
ATC code L01BB06

Mechanism of action

DNA polymerase (alpha/delta/epsilon) inhibitor

Primary target: DNA

Approval history

Authority Status Date
FDA approved
EMA approved

Pipeline programs

  1. SP_MH20VYX Phase 1 · AXIM Biotechnologies · AML

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  3. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  4. anagrelide Antineoplastic and immunomodulating agents (L01)
  5. apremilast Antineoplastic and immunomodulating agents (L04)
  6. arsenic trioxide Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is clofarabine?

clofarabine (EVOLTRA) is a dna polymerase (alpha/delta/epsilon) inhibitor. Associated with Amneal Pharma Europe Ltd. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for clofarabine?

EVOLTRA is a marketed brand name for clofarabine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of clofarabine?

clofarabine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.