Wednesday, July 8, 2026

Drug profile · INN

chlorambucil

chlorambucil (LEUKERAN) is a dna inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

FDA: approved TGA: approved NMPA: clinical trials
US status approved
Patents linked 0
Pipeline programs 5
News articles 0
Drug details — chlorambucil
US status
approved
Class
Route
ORAL
Patents
0
Programs
5
Data quality
0.84

Quick answer

chlorambucil (LEUKERAN) is a dna inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN chlorambucil
Brand LEUKERAN
Mechanism DNA inhibitor
Target DNA
Route ORAL
Formulation TABLET

Mechanism of action

DNA inhibitor

Primary target: DNA

Approval history

Authority Status Date
FDA approved
TGA approved
NMPA clinical trials

Pipeline programs

  1. ACE-CL-007 Phase 3 · Anaxis Pharma · Chronic Lymphocytic Leukemia
  2. APG2575CC301 Phase 3 · Anaxis Pharma · Newly Diagnosed Chronic Lymphocytic Leukemia/Small Lymphocyt
  3. BO25323 Phase 3 · HOFFMANN-LA ROCHE · Chronic Lymphocytic Leukemia (CLL)
  4. Chlorambucil Phase 2 · Teva Pharma · Chronic Lymphocytic Leukemia
  5. TGR-1202 + Obinutuzumab + Chlorambucil Phase 1 · TG THERAPEUTICS · Chronic Lymphocytic Leukemia

Related & competitor drugs

  1. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  2. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  3. azacitidine Antineoplastic and immunomodulating agents (L01)
  4. bleomycin sulfate DNA inhibitor
  5. busulfan Antineoplastic and immunomodulating agents (L01)
  6. capecitabine Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is chlorambucil?

chlorambucil (LEUKERAN) is a dna inhibitor. Associated with Lacuna Pharma Pty Ltd. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for chlorambucil?

LEUKERAN is a marketed brand name for chlorambucil. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of chlorambucil?

chlorambucil has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.