Wednesday, July 8, 2026

Drug profile · INN

carmustine

carmustine (GLIADEL) is a glutathione reductase inhibitor. Associated with Eisai Co.,. Route of administration: intracranial. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved Antineoplastic and immunomodulating agents (L01) L01AD01
US status approved
Patents linked 0
Pipeline programs 3
News articles 0
Drug details — carmustine
US status
approved
Class
Antineoplastic and immunomodulating agents (L01)
Route
INTRACRANIAL
Patents
0
Programs
3
Data quality
0.89

Quick answer

carmustine (GLIADEL) is a glutathione reductase inhibitor. Associated with Eisai Co.,. Route of administration: intracranial. Current US regulatory status: approved.

Key facts

INN carmustine
Brand GLIADEL
Mechanism Glutathione reductase inhibitor
Target DNA
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route INTRACRANIAL
Formulation INJECTABLE
ATC code L01AD01
Originator Eisai Co.,

Mechanism of action

Glutathione reductase inhibitor

Primary target: DNA

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved

Pipeline programs

  1. CCTL019H2301 Phase 3 · Novartis India · Adult patients with relapsed or refractory aggressive B-cell
  2. NET-MS Phase 2 · Telethon Foundation · Relapsing Remitting Multiple Sclerosis
  3. Carmustine Phase 1 · ADC Therapeutics · Recurrent Diffuse Large B-Cell Lymphoma

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. acyclovir Human herpesvirus 1 DNA polymerase inhibitor
  3. acyclovir sodium Human herpesvirus 1 DNA polymerase inhibitor
  4. anagrelide Antineoplastic and immunomodulating agents (L01)
  5. apremilast Antineoplastic and immunomodulating agents (L04)
  6. arsenic trioxide Antineoplastic and immunomodulating agents (L01)

Frequently asked questions

What is carmustine?

carmustine (GLIADEL) is a glutathione reductase inhibitor. Associated with Eisai Co.,. Route of administration: intracranial. Current US regulatory status: approved.

What is the brand name for carmustine?

GLIADEL is a marketed brand name for carmustine. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of carmustine?

carmustine has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.