Wednesday, July 8, 2026

Drug profile · INN

cabozantinib s-malate

cabozantinib s-malate (CABOMETYX) is a hepatocyte growth factor receptor inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 8
News articles 0
Drug details — cabozantinib s-malate
US status
approved
Class
Route
ORAL
Patents
0
Programs
8
Data quality
0.84

Quick answer

cabozantinib s-malate (CABOMETYX) is a hepatocyte growth factor receptor inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN cabozantinib s-malate
Brand CABOMETYX
Mechanism Hepatocyte growth factor receptor inhibitor
Target Hepatocyte growth factor receptor
Route ORAL
Formulation CAPSULE

Mechanism of action

Hepatocyte growth factor receptor inhibitor

Primary target: Hepatocyte growth factor receptor

Approval history

Authority Status Date
FDA approved

Pipeline programs

  1. 2023/3764 Phase 3 · George Institute for · Metastatic renal cell carcinoma (mRCC)
  2. CA209-9ER Phase 3 · Bristol-Myers Squibb Australia · Advanced or Metastatic Renal Cell Carcinoma
  3. CA209-8TT Phase 2 · Bristol-Myers Squibb Australia · Pan tumor
  4. CABOMETYX for bladder carcinoma of urothelial… Phase 2 · Telethon Foundation · bladder carcinoma of urothelial and non-urothelial histology
  5. CABinMET Phase 2 · Telethon Foundation · Non small-cell lung cancer
  6. F-FR-60000-023 Phase 2 · Ipsen · Unresectable, Locally Advanced or Metastatic Renal Cell Carc
  7. IB 2020-02 Phase 2 · George Institute for · Advanced /metastatic sarcomas: undifferentiated pleomorphic
  8. 2024/3873 CABOLD Approved · George Institute for · Renal carcinoma

Related & competitor drugs

  1. capmatinib hydrochloride Hepatocyte growth factor receptor inhibitor
  2. tepotinib hydrochloride Hepatocyte growth factor receptor inhibitor
  3. capmatinib Antineoplastic and immunomodulating agents (L01)
  4. tepotinib Antineoplastic and immunomodulating agents (L01)
  5. capmatinib hydrochloride hydrate Hepatocyte growth factor receptor inhibitor
  6. tepotinib hydrochloride hydrate Hepatocyte growth factor receptor inhibitor

Frequently asked questions

What is cabozantinib s-malate?

cabozantinib s-malate (CABOMETYX) is a hepatocyte growth factor receptor inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for cabozantinib s-malate?

CABOMETYX is a marketed brand name for cabozantinib s-malate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of cabozantinib s-malate?

cabozantinib s-malate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.