Friday, July 10, 2026

Drug profile · INN

botulinum toxin type a

botulinum toxin type a (BOTOX) is a synaptosomal nerve-associated protein 25 (snap-25) hydrolytic enzyme. Associated with AbbVie.

EMA: approved TGA: approved PMDA: approved Musculo-skeletal system (M03) M03AX01
Patents linked 0
Pipeline programs 16
News articles 0
Drug details — botulinum toxin type a
Class
Musculo-skeletal system (M03)
Route
Patents
0
Programs
16
Data quality
0.83

Quick answer

botulinum toxin type a (BOTOX) is a synaptosomal nerve-associated protein 25 (snap-25) hydrolytic enzyme. Associated with AbbVie.

Key facts

INN botulinum toxin type a
Brand BOTOX
Mechanism Synaptosomal nerve-associated protein 25 (SNAP-25) hydrolytic enzyme
Target Synaptosomal-associated protein 25
Therapeutic class Musculo-skeletal system (M03)
ATC code M03AX01
Originator AbbVie

Mechanism of action

Synaptosomal nerve-associated protein 25 (SNAP-25) hydrolytic enzyme

Primary target: Synaptosomal-associated protein 25

Approval history

Authority Status Date
EMA approved
TGA approved
PMDA approved

Pipeline programs

  1. APHP230823 Phase 3 · PARItec · Adults aged at least 18 years with painful base-of-thumb ost
  2. BASICstudy Phase 3 · Createrna Science and · Chronic cluster headache
  3. BOTOX Phase 3 · AbbVie · Masseter Muscle Prominence
  4. Botulinum Toxin type A (intradermal / submucosal injection at pain area) Phase 3 · First People's Hospital · Trigeminal Neuralgia
  5. Botulinum toxin type A Phase 3 · Ipsen · Low Back Pain
  6. Botulinum toxin type A Phase 3 · Hospital Authority · Obesity
  7. CLIN-52120-463 Phase 3 · Ipsen · Chronic migraine
  8. CLIN-52120-464 Phase 3 · Ipsen · Episodic Migraine

Related & competitor drugs

  1. allopurinol Musculo-skeletal system (M04)
  2. colchicine Musculo-skeletal system (M04)
  3. denosumab Musculo-skeletal system (M05)
  4. eteplirsen Musculo-skeletal system (M09)
  5. febuxostat Musculo-skeletal system (M04)
  6. ibandronic acid Musculo-skeletal system (M05)

Frequently asked questions

What is botulinum toxin type a?

botulinum toxin type a (BOTOX) is a synaptosomal nerve-associated protein 25 (snap-25) hydrolytic enzyme. Associated with AbbVie.

What is the brand name for botulinum toxin type a?

BOTOX is a marketed brand name for botulinum toxin type a. Check FDA Drugs@FDA for the current US label holder and prescribing information.