Wednesday, July 8, 2026

Drug profile · INN

belumosudil mesylate

belumosudil mesylate (REZUROCK) is a rho-associated protein kinase inhibitor. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 1
Pipeline programs 0
News articles 0
Drug details — belumosudil mesylate
US status
approved
Class
Route
ORAL
Patents
1
Programs
0
Data quality
0.84

Quick answer

belumosudil mesylate (REZUROCK) is a rho-associated protein kinase inhibitor. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN belumosudil mesylate
Brand REZUROCK
Mechanism Rho-associated protein kinase inhibitor
Target Rho-associated protein kinase
Route ORAL
Formulation TABLET

Mechanism of action

Rho-associated protein kinase inhibitor

Primary target: Rho-associated protein kinase

Approval history

Authority Status Date
FDA approved

Related & competitor drugs

  1. netarsudil mesylate Rho-associated protein kinase inhibitor
  2. belumosudil Antineoplastic and immunomodulating agents (L04)

Related patents

  1. US 11311541

    Treatment of GVHD

    Expires Mon Apr 21 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is belumosudil mesylate?

belumosudil mesylate (REZUROCK) is a rho-associated protein kinase inhibitor. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for belumosudil mesylate?

REZUROCK is a marketed brand name for belumosudil mesylate. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of belumosudil mesylate?

belumosudil mesylate has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.