Friday, July 10, 2026

Drug profile · INN

atrasentan hydrochloride

atrasentan hydrochloride (VANRAFIA) is a endothelin receptor et-a antagonist. Route of administration: oral. Current US regulatory status: approved.

FDA: approved
US status approved
Patents linked 0
Pipeline programs 0
News articles 0
Congress events 1
Drug details — atrasentan hydrochloride
US status
approved
Class
Route
ORAL
Patents
0
Programs
0
Data quality
0.84

Quick answer

atrasentan hydrochloride (VANRAFIA) is a endothelin receptor et-a antagonist. Route of administration: oral. Current US regulatory status: approved.

Key facts

INN atrasentan hydrochloride
Brand VANRAFIA
Mechanism Endothelin receptor ET-A antagonist
Target Endothelin-1 receptor
Route ORAL
Formulation TABLET

Mechanism of action

Endothelin receptor ET-A antagonist

Primary target: Endothelin-1 receptor

Approval history

Authority Status Date
FDA approved

Congress & event coverage

  • Presentation
    ASCO 2026

    1 presentation · oncology

Related & competitor drugs

  1. sparsentan Cardiovascular system (C09)

Frequently asked questions

What is atrasentan hydrochloride?

atrasentan hydrochloride (VANRAFIA) is a endothelin receptor et-a antagonist. Route of administration: oral. Current US regulatory status: approved.

What is the brand name for atrasentan hydrochloride?

VANRAFIA is a marketed brand name for atrasentan hydrochloride. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of atrasentan hydrochloride?

atrasentan hydrochloride has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.