Wednesday, July 8, 2026

Drug profile · INN

atezolizumab

atezolizumab (TECENTRIQ) is a programmed cell death 1 ligand 1 inhibitor. Associated with Hoffmann-La Roche. Route of administration: injection. Current US regulatory status: approved.

FDA: approved EMA: approved TGA: approved PMDA: approved NMPA: clinical trials Antineoplastic and immunomodulating agents (L01) L01XC32
US status approved
Patents linked 20
Pipeline programs 105
News articles 6
Drug details — atezolizumab

Quick answer

atezolizumab (TECENTRIQ) is a programmed cell death 1 ligand 1 inhibitor. Associated with Hoffmann-La Roche. Route of administration: injection. Current US regulatory status: approved.

Key facts

INN atezolizumab
Brand TECENTRIQ
Mechanism Programmed cell death 1 ligand 1 inhibitor
Target Programmed cell death 1 ligand 1
Therapeutic class Antineoplastic and immunomodulating agents (L01)
Route INJECTION
Formulation INJECTABLE
ATC code L01XC32

Mechanism of action

Programmed cell death 1 ligand 1 inhibitor

Primary target: Programmed cell death 1 ligand 1

Approval history

Authority Status Date
FDA approved
EMA approved
TGA approved
PMDA approved
NMPA clinical trials

Recent coverage

Pharma bets on PD-1/VEGF bispecifics: Is lung cancer the wrong target?
High impact Analysisnon-small cell lung cancerJun 6, 2026

Pharma bets on PD-1/VEGF bispecifics: Is lung cancer the wrong target?

FDA · non-small cell lung cancer · 5 min

While many drugmakers are focused on lung cancer for PD-1/VEGF bispecifics, emerging evidence shows the liver may offer higher value. This analysis covers the mechanism, key players, and strategic implications for pharma teams.

Dr. Sarah Mitchell
FDA Approves Atezolizumab for ctDNA MRD-Positive MIBC: A New Era for Adjuvant Therapy
High impact Newsmuscle invasive bladder cancerJun 2, 2026

FDA Approves Atezolizumab for ctDNA MRD-Positive MIBC: A New Era for Adjuvant Therapy

FDA · muscle invasive bladder cancer · 7 min

The U.S. Food and Drug Administration (FDA) has approved atezolizumab (Tecentriq) for the adjuvant treatment of adult patients with muscle-invasive bladder cancer (MIBC) who have ctDNA molecular residual disease (MRD) positivity after radical cystectomy. This approval signifies a major step forward in personalized adjuvant therapy for this patient population.

Dr. Sarah Mitchell
FDA Approves Atezolizumab for Muscle-Invasive Bladder Cancer
Medium impact NewsoncologyMay 19, 2026

FDA Approves Atezolizumab for Muscle-Invasive Bladder Cancer

FDA · oncology · 3 min

The FDA has approved Atezolizumab for muscle-invasive bladder cancer, marking a significant advancement in oncology treatment options. This approval has important implications for investors and pharmaceutical teams.

Dr. Sarah Mitchell
Roche's ctDNA-Guided Approach in Bladder Cancer: A Strategic Win
Medium impact Analysisbladder cancerMay 17, 2026

Roche's ctDNA-Guided Approach in Bladder Cancer: A Strategic Win

bladder cancer · 2 min

Roche's innovative ctDNA-guided approach for Tecentriq in post-surgical bladder cancer has garnered significant attention. This article explores the implications for pharmaceutical teams and investors.

Dr. Sarah Mitchell

Pipeline programs

  1. 1438-0012 Phase 3 · Boehringer Ingelheim · small cell lung cancer
  2. 1479-0032 Phase 3 · Boehringer Ingelheim · Non-small cell lung cancer
  3. A021502 Phase 3 · George Institute for · stage III colon adenocarcinoma with deficient MMR
  4. ABC-HCC Phase 3 · George Institute for · intermediate-stage hepatocellular carcinoma
  5. Atezolizumab Phase 3 · HOFFMANN-LA ROCHE · Melanoma
  6. Atezolizumab Phase 3 · HOFFMANN-LA ROCHE · Breast Cancer
  7. Atezolizumab Phase 3 · HOFFMANN-LA ROCHE · Carcinoma, Hepatocellular
  8. Atezolizumab Phase 3 · HOFFMANN-LA ROCHE · Urothelial Carcinoma

Related & competitor drugs

  1. abiraterone acetate Antineoplastic and immunomodulating agents (L02)
  2. anagrelide Antineoplastic and immunomodulating agents (L01)
  3. apremilast Antineoplastic and immunomodulating agents (L04)
  4. arsenic trioxide Antineoplastic and immunomodulating agents (L01)
  5. axitinib Antineoplastic and immunomodulating agents (L01)
  6. azacitidine Antineoplastic and immunomodulating agents (L01)
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    granted
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    DÉRIVÉS DE 2-AMINO-3-CYANO THIOPHÈNE ANNELÉS SPIROCYCLIQUES UTILISÉS EN TANT QU'INHIBITEURS DE KRAS POUR LE TRAITEMENT DU CANCER

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    MÉTHODE DE RÉDUCTION DE L'EXCRÉTION VIRALE, DE COLONISATION DE TISSU ET DE DÉPLÉTION LYMPHOÏDE PROVOQUÉES PAR OU ASSOCIÉES À UNE INFECTION PAR PCV2

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Frequently asked questions

What is atezolizumab?

atezolizumab (TECENTRIQ) is a programmed cell death 1 ligand 1 inhibitor. Associated with Hoffmann-La Roche. Route of administration: injection. Current US regulatory status: approved.

What is the brand name for atezolizumab?

TECENTRIQ is a marketed brand name for atezolizumab. Check FDA Drugs@FDA for the current US label holder and prescribing information.

What is the US approval status of atezolizumab?

atezolizumab has approved status in the United States according to our Drugs@FDA-derived records. Verify on the official FDA label before clinical or commercial decisions.