Friday, July 10, 2026

Drug profile · INN

alpha1-proteinase inhibitor (human)

alpha1-proteinase inhibitor (human) (RESPREEZA) is a leukocyte elastase inhibitor.

EMA: approved Blood and blood forming organs (B02) B02AB02
Patents linked 0
Pipeline programs 4
News articles 0
Drug details — alpha1-proteinase inhibitor (human)
Class
Blood and blood forming organs (B02)
Route
Patents
0
Programs
4
Data quality
0.83

Quick answer

alpha1-proteinase inhibitor (human) (RESPREEZA) is a leukocyte elastase inhibitor.

Key facts

INN alpha1-proteinase inhibitor (human)
Brand RESPREEZA
Mechanism Leukocyte elastase inhibitor
Target Neutrophil elastase
Therapeutic class Blood and blood forming organs (B02)
ATC code B02AB02

Mechanism of action

Leukocyte elastase inhibitor

Primary target: Neutrophil elastase

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. alpha1-proteinase inhibitor Phase 3 · Takeda · Covid19
  2. INBRX101-01-201 Phase 2 · Sanofi-Aventis U.S · Alpha-1 Antitrypsin Deficiency (AATD) Emphysema
  3. Alpha1-Proteinase Inhibitor Approved · Takeda · Alpha 1-Antitrypsin Deficiency
  4. Alpha1-proteinase inhibitor Approved · Takeda · Alpha1-antitrypsin Deficiency

Related & competitor drugs

  1. apixaban Blood and blood forming organs (B01)
  2. berotralstat Blood and blood forming organs (B06)
  3. bivalirudin Blood and blood forming organs (B01)
  4. c1 inhibitor (human) Blood and blood forming organs (B06)
  5. clopidogrel Blood and blood forming organs (B01)
  6. dabigatran etexilate Blood and blood forming organs (B01)

Frequently asked questions

What is alpha1-proteinase inhibitor (human)?

alpha1-proteinase inhibitor (human) (RESPREEZA) is a leukocyte elastase inhibitor.

What is the brand name for alpha1-proteinase inhibitor (human)?

RESPREEZA is a marketed brand name for alpha1-proteinase inhibitor (human). Check FDA Drugs@FDA for the current US label holder and prescribing information.