Friday, July 10, 2026

Drug profile · INN

c1 inhibitor (human)

c1 inhibitor (human) (CINRYZE) is a coagulation factor xi inhibitor. Associated with Takeda.

EMA: approved Blood and blood forming organs (B06) B06AC01
Patents linked 0
Pipeline programs 12
News articles 0
Drug details — c1 inhibitor (human)
Class
Blood and blood forming organs (B06)
Route
Patents
0
Programs
12
Data quality
0.89

Quick answer

c1 inhibitor (human) (CINRYZE) is a coagulation factor xi inhibitor. Associated with Takeda.

Key facts

INN c1 inhibitor (human)
Brand CINRYZE
Mechanism Coagulation factor XI inhibitor
Target Coagulation factor XI
Therapeutic class Blood and blood forming organs (B06)
ATC code B06AC01
Originator Takeda

Mechanism of action

Coagulation factor XI inhibitor

Primary target: Coagulation factor XI

Approval history

Authority Status Date
EMA approved

Pipeline programs

  1. CINRYZE 500 Phase 3 · Takeda · Hereditary Angioedema (HAE)
  2. CINRYZE 500 U Phase 3 · Takeda · Hereditary Angioedema (HAE)
  3. Cinryze® Phase 3 · Takeda · Acute Antibody-Mediated Rejection (AMR)
  4. C1 Esterase Inhibitor Injection [Cinryze] Phase 2 · Takeda · Subarachnoid Hemorrhage, Aneurysmal
  5. C1 Inhibitor, Human Phase 2 · Takeda · Traumatic Brain Injury
  6. CINRYZE Phase 2 · Takeda · Hereditary Angioedema
  7. CINRYZE Phase 2 · Takeda · Hereditary Angioedema (HAE)
  8. CINRYZE with rHuPH20 Phase 2 · Takeda · Hereditary Angioedema (HAE)

Related & competitor drugs

  1. apixaban Blood and blood forming organs (B01)
  2. berotralstat Blood and blood forming organs (B06)
  3. bivalirudin Blood and blood forming organs (B01)
  4. clopidogrel Blood and blood forming organs (B01)
  5. dabigatran etexilate Blood and blood forming organs (B01)
  6. eltrombopag Blood and blood forming organs (B02)

Frequently asked questions

What is c1 inhibitor (human)?

c1 inhibitor (human) (CINRYZE) is a coagulation factor xi inhibitor. Associated with Takeda.

What is the brand name for c1 inhibitor (human)?

CINRYZE is a marketed brand name for c1 inhibitor (human). Check FDA Drugs@FDA for the current US label holder and prescribing information.