pharma · Hemophagocytic lymphohistiocytosis (HLH) · Multiple sclerosis
PARItec
Pari Pharma GmbH
PARItec trial registry — 248 ClinicalTrials.gov studies with program phase, status, and indication context.
Company details
- Status
- Public
- HQ
- Starnberg, DE
- Employees
- 28
- Programs
- 248
- Drugs
- 362
- Patents
- 0
PARItec clinical trials
Registry index of 248 ClinicalTrials.gov studies linked to PARItec programs — each row shows trial ID, program name, phase, status, and indication.
PARItec trial registry — 248 ClinicalTrials.gov studies with program phase, status, and indication context.
Recent trial activity
Latest clinical program signals indexed for PARItec.
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APHP220916 — Phase 2
Clinical update -
APHP211046 — Phase 3
Clinical update -
A phase 2 trial assessing Ifenprodil as a ReM... for Multiple sclerosis — Phase 2
Clinical update -
Kineret / solution for Familial Mediterranean Fever (F… — Phase 3
Clinical update -
P170916J — Phase 3
Clinical update -
P170913J — Phase 3
Clinical update -
P160925J — Phase 3
Clinical update -
P160909 — Phase 2
Clinical update
Trial registry
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CTIS ↗ - 2023-503283-17-00CTIS ↗
APHP220806
Women who delivered by caesarean and have a moderate postpartum iron deficiency anaemia defined by 8.0 g/dL ≤ postoperative Hb level ≤ 10.0 g/dL within 72h after delivery and a ferritinemia ≤ 100 ng/mL OR transferrin saturation ≤ 20% (Measured after postoperative Hb level measurement)
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CTIS ↗ - 2023-504511-32-00CTIS ↗
APHP211046
Any patients ≥18 years old, eligible for transfemoral TAVI with coverage for medical insurance
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CTIS ↗ - 2023-505278-13-00CTIS ↗
APHP220916
-women with an inflammatory HCA proven at histology and with at least one inflammatory HCA of more than 5 cm. -male with at least one inflammatory HCA proven at histology whatever the size and considered as non resectable by the multidisciplinary tumor board
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CTIS ↗ - 2023-505500-37-00CTIS ↗
APHP220670
Pregnant women with singleton pregnancies hospitalized for threatened late miscarriage with intact membranes
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CTIS ↗ - 2023-505510-26-00CTIS ↗
APHP220800
Patients in ICU with invasive mechanical ventilation and HSV throat reactivation with 1 or no organ failures.
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CTIS ↗ - 2023-506598-36-00CTIS ↗
Solution de chlorure de sodium à 0 for Adult Patients kidney transplan…
Adult Patients kidney transplant recipients who have developed chronic humoral rejection, diagnosed through a kidney biopsy (Banff 2017 Classification), resistant to conventional treatment (3 injections at one-month intervals of 2g/kg of IVIG)
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CTIS ↗ - 2023-506721-11-00CTIS ↗
Kineret / solution for Familial Mediterranean Fever (F…
Familial Mediterranean Fever (FMF)
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CTIS ↗ - 2023-507010-27-00CTIS ↗
APHP211003
Primary Bilateral Macronodular Adrenal Hyperplasia causing moderate Cushing Syndrome (Mild autonomous Cortisol secretion)
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CTIS ↗ - 2023-507334-24-00CTIS ↗
MUNC13.4-CD34 suspension, MUNC13.4-T3 suspension
Familial Hemophagocytic Lymphohistiocytosis (FHL)
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CTIS ↗ -
CTIS ↗ - 2023-507874-42-00CTIS ↗
A phase 2 trial assessing Ifenprodil as a ReM... for Multiple sclerosis
Multiple sclerosis
- 2023-508071-36-00CTIS ↗
APHP191099
Patients hospitalised in intensive care, diagnosed with sepsis less than 48 hours ago, uric acid level ≥200µmol/L, adults, negative G6PD deficiency
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CTIS ↗ - 2023-508535-32-00CTIS ↗
METFORMIN , Placebo 515
Portal hypertension (PHT) and consequences in complications of cirrhosis
- 2023-508785-16-00CTIS ↗
APHP230813
Very preterm neonate (gestational age at birth < 32 WG) with corrected gestational age <45 WG) with indication for sedation in the context of invasive mechanical ventilation
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CTIS ↗ - 2023-508930-33-00CTIS ↗
APHP230848
Non-infectious active cryoglobulinemia vasculitis who are either refractory or intolerant to Rituximab
- 2023-509722-22-00CTIS ↗
APHP221166
gram-negative bacillus pneumonia acquired during mechanical ventilation in patients receiving Extracorporeal Membrane veno-arterial oxygenation
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CTIS ↗ -
CTIS ↗ - 2023-510253-42-00CTIS ↗
APHP220273
Adult patients aged 18 and over with unicentric hyalino-vascular Castleman's disease
- 2023-510261-94-00CTIS ↗
APHP230844
Adult patients with severe cardiogenic shock on venoarterial ECMO support for less than 24 hours.
- 2023-510262-27-00CTIS ↗
APHP220673
newly diagnosed or relapsing deep venous thrombosis related to Behçet’s syndrome
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CTIS ↗ -
CTIS ↗ - 2024-510580-28-00CTIS ↗
IRINOTECAN for Middle or low locally advanced resectable rectal carcinoma
Middle or low locally advanced resectable rectal carcinoma
- 2024-510602-90-00CTIS ↗
APHP230855
Patients presenting with acute myocarditis proven by cardiac magnetic resonance imaging (CMRi) or by histological evidence on endomyocardial biopsy (EMB)
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CTIS ↗ - 2024-510941-32-00CTIS ↗
APHP220826
Adult patients discharged alive from ICU with a decreased eGFR, and/or an AKI during ICU stay and/or an elevated NT-proBNP at discharge.
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CTIS ↗ - 2024-510981-18-00CTIS ↗
APHP231089
Multiple Myeloma Multiple myeloma (MM) is a B cell malignancy and is one of the most frequent primary neoplasms of the bone marrow
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CTIS ↗ - 2024-511437-35-00CTIS ↗
SARCLISA for Patients aged 18-65 years old w…
Patients aged 18-65 years old with newly diagnosed previously untreated ALL or T-LL.
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CTIS ↗ - 2024-511858-44-00CTIS ↗
Cell therapy for Inclusion Body Myositis (IBM... for Inclusion Body Myositis
Inclusion Body Myositis
- 2024-511862-35-00CTIS ↗
P160954J
Adults with non-contrast-enhancing diffuse brainstem gliomas with non-threatening infiltrative clinical and/or radiological progression, Adult brain stem gliomas
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CTIS ↗ - 2024-511866-36-00CTIS ↗
APHP211034
patients hospitalized in ICU with ESBL-producing Enterobacteriaceae severe infection
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CTIS ↗ - 2024-511870-65-00CTIS ↗
APHP180591
Adults Non Diabete Remission (NDR) Type 2 Diabete (T2D) patients 1 to 5 years after bariatric surgery
- 2024-511880-27-00CTIS ↗
APHP200080
Newly diagnosed Glioblastoma (IDH wild-type) patients at initial radiological diagnosis eligible for tumor resection, and for the standard of care including concurrent temoradiation followed by adjuvant TMZ with or without Tumor Treating Fields*. (*Tumor Treating Fields is applicable only in participating centers in France)
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CTIS ↗ - 2024-511896-13-00CTIS ↗
APHP210085
EA-COPD (with mechanical ventilation, invasive or non-invasive, or high-flow nasal oxygen therapy).
- 2024-511897-64-00CTIS ↗
Regiocit solution pour hémofiltration
Adult patients hospitalized in intensive care with an indication of EER with ARC during the stay.
- 2024-511898-30-00CTIS ↗
DEXMEDETOMIDINE , 18F-DPA-714
Patients who survive a COVID ARDS in intensive care must be weaned off invasive mechanical ventilation as quickly as possible. 60% of these patients present with intensive care delirium, a serious event that causes excess mortality and potential acute and late complications, since 30% of patients who present with delirium develop cognitive sequelae. Severe neuroinflammation is considered to be one of the main pathophysiological mechanisms causing delirium during ventilatory weaning. In addition to its sedative properties, dexmedetomidine has neuroprotective effects. In certain experimental models, it reduces cerebral inflammation by acting directly on the microglial phenotype. The role of this chronic neuroinflammatory state on cognitive capacity and reserve is beginning to emerge in the literature, regardless of the initial stress (surgery, head injury or Alzheimer's-type dementia), and is therefore capable of influencing patients' quality of life. The assessment of this neuroinflammation using non-invasive tools would appear to be of prime importance in the management of post-COVID neuro injured patients, as well as the evaluation of potential neuroprotective agents such as dexmedetomidine.
- 2024-511899-32-00CTIS ↗
APHP180612
Dermatomyositis; Baricitinib in patients with relapsing or naïve dermatomyositis.
- 2024-511900-17-00CTIS ↗
Dose dense re-challenge of high dose methotre...
Oncology: RELAPSED PRIMARY CNS LYMPHOMA
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CTIS ↗ - 2024-511906-21-00CTIS ↗
TOCILIZUMAB, Placebo of Tocilizumab
Giant cell arteritis with Cerebro-vascular involvement
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CTIS ↗ - 2024-512758-62-00CTIS ↗
GADOTERIC ACID, [18F]fludarabine
Patients with newly diagnosed primary central nervous system lymphoma naïve to surgery, radiotherapy or chemotherapy
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CTIS ↗ - 2024-512763-32-00CTIS ↗
APHP230852
Patients diagnosed at the study sites with rifampicinresistant tuberculosis during the recruitment period will be evaluated for study inclusion.
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CTIS ↗ - 2024-513330-38-00CTIS ↗
APHP221107
Healthy volunteers : Healthy adults with no history of gastrointestinal disease Patients with IBD in remission
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CTIS ↗ - 2024-513427-17-00CTIS ↗
Xolair 75 mg solution for injection in pre-filled syringe
Well controlled severe allergic asthma
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CTIS ↗ - 2024-513490-45-00CTIS ↗
APHP210089
Patients hospitalized for allogeneic hematopoietic stem cell transplantation
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CTIS ↗ - 2024-513645-37-00CTIS ↗
P170912J
Adult patients with indication for conventional cardiac surgery (CABG, aortic replacement, or ascending aorta surgery)
- 2024-513647-86-00CTIS ↗
P160906J
Patients displaying a non-classified, severe and resistant inflammatory disease
- 2024-513648-27-00CTIS ↗
Itacitinib, placebo of itacitinib 100mg
Patients with newly or active diffuse Systemic sclerosis (SSc) at the time of screening
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CTIS ↗ -
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CTIS ↗ - 2024-513652-15-00CTIS ↗
ARTEGENE
Severe Combined Immuno-Deficiency (SCID) caused by biallelic mutations in the Artemis gene (DCLRE1C)
- 2024-513653-75-00CTIS ↗
D20180135
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome
- 2024-513669-38-00CTIS ↗
COLCHICINE OPOCALCIUM 1 mg, comprimé sécable
Stroke, Ischemic, TIA, Cardiac Disease, Atherosclerosis, Myocardial Infarction, Coronary Syndrome, Cerebral Infarction
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CTIS ↗ - 2024-513672-17-00CTIS ↗
Placebo de macitentan 10 mg, MACITENTAN
Inoperable Chronic thromboembolic pulmonary hyperTension, Pneumology
- 2024-513710-35-00CTIS ↗
APHP230836
Patients presenting to ENT emergencies with a unilateral sudden sensorineural hearing loss (SSNHL). SSNHL is defined according to the American ENT society guidelines criteria as a subset of SSNHL that is sensorineural in nature, occurs within a 72 hour window, and consists of a decrease in hearing of ≥30 decibels affecting at least 3 consecutive frequencies: 1. A history of an idiopathic and unilateral sudden decrease in hearing > 72 hours and <15 days. 2. A unilateral sensorineural hearing loss demonstrable on a pure‐tone audiogram at the time of entry into the trial. 3. No other neurological signs except the eight cranial nerve defect; no other types of hearing loss as conductive forms of hearing impairment. 4. No history of fluctuating sensorineural hearing loss or otologic disease.
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CTIS ↗ - 2024-514243-29-01CTIS ↗
PEGASPARGASE
This is a prospective, French, multicenter, open-label, design, stratified on the immunophenotypic characterization (B- or T- lineage) and the patient risk group, that aims at evaluating the efficacy and the tolerance of different schedules of pegaspargase in patients from 12 months to less than 18 years newly diagnosed with standard/medium-risk ALL
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CTIS ↗ -
CTIS ↗ - 2024-514345-11-00CTIS ↗
APHP200132
children, adolescents and young adults with Acute Lymphoblastic Leukemia
- 2024-514347-28-00CTIS ↗
APHP180560
Men and women over 18 years of age with renal failure renal failure stages 3b/4/5, renal transplantation or dialysis and an untreated gout attack
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CTIS ↗ - 2024-514351-14-00CTIS ↗
SARCLISA 20mg/mL concentrate for solution for infusion.
Pure cell red aplasia by major ABO mismatch after allogeneic hematopoietic stem cell transplantation
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CTIS ↗ - 2024-514400-14-00CTIS ↗
BEVACIZUMAB, ATEZOLIZUMAB
liver transplanted patients with advanced hepatocellular carcinoma
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CTIS ↗ -
CTIS ↗ - 2024-514606-31-00CTIS ↗
LENVIMA 4 mg hard capsules
Patients with Biopsy-proven or radiologically-suggested BCLC A HCC eligible for PA and comprising at least one of the following criteria: - Single tumour>3 cm≤ 5cm or - multiple tumours (max 3 lesions ≤ 3cm) or - Single tumour between 2 and 3 cm with at least one of the following characteristic: • Serum AFP>100 ng/mL • Infiltrative form • Macro-trabecular subtype (if applicable)
- 2024-514609-76-00CTIS ↗
SIROLIMUS
Adult patients (men and women) (≥ 18 years of age) with cutaneous sarcoidosis involving the face
- 2024-514610-13-00CTIS ↗
APHP211429
patients suffering from acute myocarditis confirmed on Cardiac magnetic resonance imaging.
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CTIS ↗ - 2024-515018-42-00CTIS ↗
APHP200042
Patients treated with lithium carbonate for a bipolar disorder treated for at least 5 years and with a urine concentration defect.
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CTIS ↗ - 2024-515028-35-00CTIS ↗
APHP230823
Adults aged at least 18 years with painful base-of-thumb osteoarthritis
- 2024-515037-15-00CTIS ↗
APHP190205
PRIMARY PLASMA CELL LEUKEMIA: A PROSPECTIVE PHASE II STUDY INCORPORATING DARATUMUMAB TO CHEMOTHERAPY AND STEM CELL TRANSPLANTATION
- 2024-515038-34-00CTIS ↗
DONEPEZIL, DONEPEZIL
Interest of adding donepezil to the non-medicinal care pathway recommended in France for Alzheimer's disease
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CTIS ↗ - 2024-515308-38-00CTIS ↗
P160913
Adults patients with isolated acute urticaria presenting to the emergency department
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CTIS ↗ - 2024-516058-23-00CTIS ↗
APHP210090
Adult patients admitted to the ICU for management of severe influenza infection requiring orotracheal intubation for invasive mechanical ventilation
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CTIS ↗ - 2024-516105-23-01CTIS ↗
Jakavi tablets for haemophagocytic lymphohistiocytosis (HLH) in children
haemophagocytic lymphohistiocytosis (HLH) in children
- 2024-516167-86-00CTIS ↗
APHP200072
Patients referred for an isolated or a combined surgical correction of functional moderate to severe tricuspid regurgitation
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CTIS ↗ - 2024-516243-81-00CTIS ↗
APHP211057
myelin oligodendrocytes glycoprotein antibody associated diseases (MOGAD)
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CTIS ↗ - 2024-516373-77-00CTIS ↗
SODIUM for Adult cardiac arrest patients w…
Adult cardiac arrest patients with sustained ROSC and hemodynamic failure due to post-resuscitation syndrome
- 2024-516374-29-00CTIS ↗
APHP200002
Patients with excessive supraventricular ectopies or short atrial runs (ESVEA) defined as ≥ 1% premature atrial contractions (PAC) /24 hours or any atrial runs ≥ 20 PACs (but shorter than 30 seconds) on a 24-hour Holter ECG monitoring and CHA2DS2VASC score ≥ 3. Patients with any atrial runs ≥ 20 PACs but shorter than 30 seconds on a 15-21 days Holter ECG monitoring and CHA2DS2VASC score ≥ 3 may also be included in the Short-Run trial.
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CTIS ↗ - 2024-516402-32-00CTIS ↗
ECULIZUMAB , ECULIZUMAB
Adult patients with aHUS associated with HE and severe kidney involvement (needing dialysis or serum creatinine ≥ 354μM)
- 2024-516403-16-00CTIS ↗
APHP200017
Adult patients with immune thrombocytopenia (ITP) with mild to severe bleeding manifestations
- 2024-516404-42-00CTIS ↗
P150941J
Adults diagnosed with SJS-TEN with at least 10% of body surface area involved
- 2024-516407-16-00CTIS ↗
APHP191110
Patients admitted to the ICU proven or suspected infection as the main diagnosis.
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CTIS ↗ - 2024-516409-22-00CTIS ↗
METFORMIN
Type 2 Diabetes complete remission after bariatric surgery under antidiabetic drug
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CTIS ↗ - 2024-516687-28-00CTIS ↗
APHP200026
Patients with GPA and inadequate response to standard of care therapy defined as an inadequate response to either a combination of glucocorticoids plus cyclophosphamide AND/OR a combination of glucocorticoids plus rituximab.
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CTIS ↗ - 2024-518195-31-00CTIS ↗
Repatha 140 mg solution for injection in pre-filled pen
acute myocardial infarction
- 2024-518455-28-00CTIS ↗
Arvisol placebo, Arvisol 150mg
Patients with severe Alcohol Use Disorder (according to DSM 5) at entry of a scheduled inpatient alcohol cessation attempt
- 2024-518739-12-00CTIS ↗
APHP231308
Major patients intoxicated by functional toxicant(s), hospitalized in intensive care and intubated.
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CTIS ↗ - 2024-519986-23-00CTIS ↗
CYCLOPHOSPHAMIDE
The study will involve adult women and men from 16 French centers who have hematological malignancies and are candidates for haploidentical HSCT
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CTIS ↗ - 2024-520308-24-00CTIS ↗
BEVACIZUMAB
Adult patients with persistent dyspnea more than 3 months after acute COVID-19 infection.
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CTIS ↗ - 2024-520414-21-00CTIS ↗
Metalyse 5 000 units (25 mg) powder for solution for injection
Adult patients with a LVOS with large core within 9 hours of symptoms onset or last seen well, or with a diffusion weighted imaging (DWI)-fluid attenuated inversion recovery (FLAIR) mismatch in case of unknown onset.
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CTIS ↗ - 2025-520573-39-00CTIS ↗
MUCODRILL for Ultra High Risk of psychosis an…
Ultra High Risk of psychosis and first episode psychosis
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CTIS ↗ - 2025-520678-20-00CTIS ↗
APHP240804
Adult patients with symptomatic and inflammatory Hand osteoarthritis HOA.
- 2025-520842-31-00CTIS ↗
APHP230841
Population of study participants Pregnant women with PPROM at 22 to 33 weeks’ gestation
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CTIS ↗ - 2025-520959-90-00CTIS ↗
Atomoxetin STADA 40 mg Hartkapseln, GELATIN
Healthy subjects with no neurological or psychiatric disorders
- 2025-521090-14-00CTIS ↗
DEXAMETHASONE for Patients with relapsed/refracto…
Patients with relapsed/refractory symptomatic multiple myeloma (MM)
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CTIS ↗ - 2025-521161-27-00CTIS ↗
Epidyolex 100 mg/ml oral solution
Children and adolescents with severe neurodevelopmental disorders
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CTIS ↗ - 2025-521331-36-00CTIS ↗
APHP240909
Patient with stabilized SSc-ILD (as defined by a decline of FVC ≤ 5%) following RTX induction treatment
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CTIS ↗ - 2025-521571-30-00CTIS ↗
APHP241013
Young Adults and adults with R/R B-cell acute lymphoblastic leukemia (BCP-ALL) or a B cell lymphoma (BCL)
- 2025-521891-78-00CTIS ↗
APHP241011
Adult patients with stage IV non squamous non-small cell lung cancer (NSCLC)
- 2025-521967-11-00CTIS ↗
APHP241595
The study population includes adult ICU patients with a hospitalization of more than 48 hours. We have chosen to include patients with or without mechanical ventilation, as sleep disorders affect all ICU patients after 48 hours.
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CTIS ↗ - 2025-522546-52-00CTIS ↗
APHP 230842
patients with chronic respiratory insufficiency due to amyotrophic lateral sclerosis.
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CTIS ↗ - 2025-523137-25-00CTIS ↗
MEDITOP/2025/01
Comparative bioequivalence study in healthy volunteers under fasting conditions.
- 2025-523149-80-00CTIS ↗
APHP240938
Adult patients admitted to the ICU and receiving unplanned invasive mechanical ventilation
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CT.gov ↗