Wednesday, June 10, 2026

pharma Β· Type 2 Diabetes Mellitus Β· Irritable Bowel Syndrome Β· LXRX

LEXICON PHARMACEUTICALS

LEXICON PHARMACEUTICALS drug portfolio β€” 27 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

8800 Technology Forest, The Woodlands, TX 77381, US HQ
1995 Founded
282 Employees
Public company Type
LXRX Β· NYSE Ticker
Company details
Status
Public
HQ
8800 Technology Forest, The Woodlands, TX 77381, US
Founded
1995
Employees
282
Programs
51
Drugs
27
Patents
102
Intelligence Β· Drug Pipeline

LEXICON PHARMACEUTICALS pipeline

Portfolio lens on 27 drugs and development assets β€” regulatory status, targets, and deep links to NovaPharmaNews drug profiles.

LEXICON PHARMACEUTICALS drug portfolio β€” 27 indexed compounds with therapeutic class and molecular targets from public FDA and regional approval metadata.

Drug portfolio

27 compounds
  1. US regulatory status: approved. Molecular target: Fatty-acid amide hydrolase 1.

    Target
    Fatty-acid amide hydrolase 1
    Mechanism
    Cyclooxygenase inhibitor
  2. US regulatory status: approved. Molecular target: Dopamine receptors; D2 & D3.

    Target
    Dopamine receptors; D2 & D3
    Mechanism
    Serotonin (5-HT) receptor antagonist
  3. US regulatory status: approved. Molecular target: Bacterial penicillin-binding protein.

    Target
    Bacterial penicillin-binding protein
    Mechanism
    Bacterial penicillin-binding protein inhibitor
  4. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  5. US regulatory status: approved. Mechanism: Unknown.

    Mechanism
    Unknown
  6. US regulatory status: approved. Molecular target: Sodium/potassium-transporting ATPase.

    Target
    Sodium/potassium-transporting ATPase
    Mechanism
    Sodium/potassium-transporting ATPase inhibitor
  7. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  8. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records. Mechanism: Histamine H1 receptor antagonist.

    Mechanism
    Histamine H1 receptor antagonist
  9. US regulatory status: approved. Molecular target: Histamine H1 receptor.

    Target
    Histamine H1 receptor
    Mechanism
    Histamine H1 receptor antagonist
  10. US regulatory status: approved. Mechanism: DNA polymerase (alpha/delta/epsilon) inhibitor.

    Mechanism
    DNA polymerase (alpha/delta/epsilon) inhibitor
  11. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  12. US regulatory status: approved.

  13. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  14. US regulatory status: approved. Molecular target: Potassium-transporting ATPase.

    Target
    Potassium-transporting ATPase
    Mechanism
    Potassium-transporting ATPase inhibitor
  15. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  16. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  17. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records. Mechanism: HMG-CoA reductase inhibitor.

    Mechanism
    HMG-CoA reductase inhibitor
  18. sotagliflozin

    Alimentary tract and metabolism (A10)

    US regulatory status: approved. Molecular target: Sodium/glucose cotransporter 1.

    Target
    Sodium/glucose cotransporter 1
    Mechanism
    Sodium/glucose cotransporter 2 inhibitor
  19. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records. Mechanism: HERG blocker.

    Mechanism
    HERG blocker
  20. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  21. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  22. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  23. telotristat ethyl

    Alimentary tract and metabolism (A16)

    Alimentary tract and metabolism (A16) compound in LEXICON PHARMACEUTICALS's portfolio. Molecular target: Tryptophan 5-hydroxylase.

    Target
    Tryptophan 5-hydroxylase
    Mechanism
    Tryptophan 5-hydroxylase inhibitor
  24. US regulatory status: approved. Molecular target: Tryptophan 5-hydroxylase.

    Target
    Tryptophan 5-hydroxylase
    Mechanism
    Tryptophan 5-hydroxylase inhibitor
  25. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.

  26. Development asset linked to LEXICON PHARMACEUTICALS in public FDA and regional records.