Wednesday, June 10, 2026
🇺🇸 FDA

pharma · Hypertriglyceridemia · Type 2 Diabetes Mellitus · IONS

IONIS PHARMACEUTICALS

IONIS PHARMACEUTICALS INC

IONIS PHARMACEUTICALS clinical programs — 32 development programs from ClinicalTrials.gov with phase, modality, indication, and trial identifiers.

Website Investor relations
2855 Gazelle Ct, Carlsbad, CA 92010, US HQ
1989 Founded
1,493 Employees
Public company Type
IONS · NYSE Ticker
Company details
Status
Public
HQ
2855 Gazelle Ct, Carlsbad, CA 92010, US
Founded
1989
Employees
1,493
Programs
128
Drugs
48
Patents
222
Official website ↗ All projects Drug pipeline Patents News & analysis

Recent coverage

View all news & analysis →
Intelligence · Clinical Programs

IONIS PHARMACEUTICALS projects

32 ClinicalTrials.gov programs sponsored by IONIS PHARMACEUTICALS.

IONIS PHARMACEUTICALS has 32 clinical development programs indexed from ClinicalTrials.gov, including phase, modality, indication text, and linked NCT identifiers.

All phases Phase III Phase II Phase I NDA / BLA filed Approved programs

32 programs

Clinical programs

  1. 262SP101(ION464-CS1)

    IONIS PHARMACEUTICALS INC

    Multiple System Atrophy

    phase 1 other active

    1 trial

  2. APOC-III-L-Rx

    IONIS PHARMACEUTICALS INC

    Elevated Triglycerides (TG)

    phase 1 small molecule completed

    1 trial

  3. AZD9150

    IONIS PHARMACEUTICALS INC

    Advanced Adult Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  4. BIIB094

    IONIS PHARMACEUTICALS INC

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  5. Eplontersen

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  6. ION251

    IONIS PHARMACEUTICALS INC

    Relapsed Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  7. ION269

    IONIS PHARMACEUTICALS INC

    Alzheimer Disease

    phase 1 small molecule terminated

    1 trial

  8. ION269-CS1

    IONIS PHARMACEUTICALS INC

    Alzheimer’s Disease in Individuals with Down Syndrome

    phase 1 other active

    1 trial

  9. ION356

    IONIS PHARMACEUTICALS INC

    Pelizaeus-Merzbacher Disease

    phase 1 small molecule active

    1 trial

  10. ION464

    IONIS PHARMACEUTICALS INC

    Multiple System Atrophy

    phase 1 small molecule active

    1 trial

  11. ION537

    IONIS PHARMACEUTICALS INC

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  12. ION547

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  13. ION904

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  14. IONIS ANGPTL3-LRx

    IONIS PHARMACEUTICALS INC

    Hypertriglyceridemia

    phase 1 small molecule completed

    1 trial

  15. IONIS FXI-LRx

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  16. IONIS MAPTRx

    IONIS PHARMACEUTICALS INC

    Mild Alzheimer's Disease

    phase 1 small molecule completed

    1 trial

  17. IONIS TMPRSS6-Lrx

    IONIS PHARMACEUTICALS INC

    Thalassemia

    phase 1 small molecule completed

    1 trial

  18. IONIS-APO(a)-LRx

    IONIS PHARMACEUTICALS INC

    Elevated Lipoprotein(a)

    phase 1 small molecule completed

    1 trial

  19. IONIS-ENaCRx

    IONIS PHARMACEUTICALS INC

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  20. ISIS 325568

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  21. ISIS 333611

    IONIS PHARMACEUTICALS INC

    Familial Amyotrophic Lateral Sclerosis

    phase 1 small molecule completed

    1 trial

  22. ISIS 353512

    IONIS PHARMACEUTICALS INC

    Inflammatory Diseases

    phase 1 small molecule completed

    1 trial

  23. ISIS 388626

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  24. ISIS 681257

    IONIS PHARMACEUTICALS INC

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  25. Ionis AGT-LRx

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  26. Olezarsen

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  27. Placebo

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  28. Placebo

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  29. Volanesorsen

    IONIS PHARMACEUTICALS INC

    Abnormalities, Cardiovascular

    phase 1 small molecule completed

    1 trial

  30. mipomersen

    IONIS PHARMACEUTICALS INC

    Healthy Volunteer

    phase 1 small molecule completed

    3 trials

  31. mipomersen sodium

    IONIS PHARMACEUTICALS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  32. warfarin sodium

    IONIS PHARMACEUTICALS INC

    Healthy

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many clinical projects does IONIS PHARMACEUTICALS have?

32 published programs are linked to this sponsor in our ClinicalTrials.gov index.

Is this the complete company pipeline?

This directory lists published programs for the sponsor in our database. Partnered or out-licensed assets may appear under multiple companies.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.