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Intelligence · Clinical Pipeline

IONIS PHARMACEUTICALS Pipeline

All ClinicalTrials.gov programs at IONIS PHARMACEUTICALS — phase, modality, and trial IDs.

Programs
63

Quick answer

IONIS PHARMACEUTICALS has 63 clinical development programs indexed from ClinicalTrials.gov, including phase, modality, indication text, and linked NCT identifiers.

  1. AKCEA-ANGPTL3-LRX

    IONIS PHARMACEUTICALS INC

    Homozygous Familial Hypercholesterolemia

    phase 2 small molecule terminated

    1 trial

  2. AKCEA-ANGPTL3-LRx

    IONIS PHARMACEUTICALS INC

    Familial Chylomicronemia Syndrome

    phase 2 small molecule completed

    1 trial

  3. AKCEA-ANGPTL3-LRx

    IONIS PHARMACEUTICALS INC

    Familial Partial Lipodystrophy

    phase 2 small molecule completed

    1 trial

  4. Alicaforsen

    IONIS PHARMACEUTICALS INC

    Ulcerative Colitis

    phase 2 small molecule completed

    2 trials

  5. Fomivirsen sodium

    IONIS PHARMACEUTICALS INC

    Cytomegalovirus Retinitis

    phase 2 small molecule completed

    4 trials

  6. GHR-LRX

    IONIS PHARMACEUTICALS INC

    Acromegaly

    phase 2 small molecule completed

    1 trial

  7. ION-682884

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 2 small molecule completed

    1 trial

  8. ION-827359

    IONIS PHARMACEUTICALS INC

    Chronic Bronchitis

    phase 2 small molecule terminated

    1 trial

  9. ION224

    IONIS PHARMACEUTICALS INC

    Steatohepatitis, Nonalcoholic

    phase 2 small molecule completed

    1 trial

  10. ION337

    IONIS PHARMACEUTICALS INC

    Dravet Syndrome

    phase 2 small molecule active

    1 trial

  11. ION373, Artificial Cerebrospinal Fluid (aCSF) for injection

    IONIS PHARMACEUTICALS INC

    Alexander Disease

    phase 2 small molecule active

    1 trial

  12. ION440

    IONIS PHARMACEUTICALS INC

    Methyl CpG binding protein 2 (MECP2) Duplication Syndrome (MDS)

    phase 2 small molecule active

    1 trial

  13. ION440

    IONIS PHARMACEUTICALS INC

    Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

    phase 2 small molecule active

    1 trial

  14. ION582

    IONIS PHARMACEUTICALS INC

    Angelman syndrome

    phase 2 small molecule active

    1 trial

  15. ION717

    IONIS PHARMACEUTICALS INC

    Prion Disease

    phase 2 small molecule active

    1 trial

  16. ION775

    IONIS PHARMACEUTICALS INC

    Hypertriglyceridemia

    phase 2 small molecule active

    1 trial

  17. ION904

    IONIS PHARMACEUTICALS INC

    Hypertension

    phase 2 small molecule completed

    1 trial

  18. IONIS DGAT2Rx

    IONIS PHARMACEUTICALS INC

    Hepatic Steatosis

    phase 2 small molecule completed

    1 trial

  19. IONIS GHR-LRx

    IONIS PHARMACEUTICALS INC

    Acromegaly

    phase 2 small molecule completed

    2 trials

  20. IONIS-AGT-LRx

    IONIS PHARMACEUTICALS INC

    Chronic Heart Failure With Reduced Ejection Fraction

    phase 2 small molecule completed

    1 trial

  21. IONIS-DMPKRx

    IONIS PHARMACEUTICALS INC

    Myotonic Dystrophy Type 1

    phase 2 small molecule completed

    1 trial

  22. IONIS-FB-LRx

    IONIS PHARMACEUTICALS INC

    Macular Degeneration

    phase 2 small molecule completed

    1 trial

  23. IONIS-FB-LRx

    IONIS PHARMACEUTICALS INC

    Primary IgA Nephropathy

    phase 2 small molecule completed

    1 trial

  24. IONIS-FB-Lrx

    IONIS PHARMACEUTICALS INC

    Geographic Atrophy

    phase 2 small molecule terminated

    1 trial

  25. IONIS-HBVRx

    IONIS PHARMACEUTICALS INC

    Hepatitis B

    phase 2 small molecule completed

    1 trial

  26. IONIS-PKKRx (ISIS 546254)

    IONIS PHARMACEUTICALS INC

    Chronic Migraine

    phase 2 small molecule completed

    1 trial

  27. IONIS-STAT3Rx

    IONIS PHARMACEUTICALS INC

    Advanced Cancers

    phase 2 small molecule completed

    1 trial

  28. ISIS 104838

    IONIS PHARMACEUTICALS INC

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  29. ISIS 113715

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 2 small molecule completed

    5 trials

  30. ISIS 14803

    IONIS PHARMACEUTICALS INC

    Hepatitis C, Chronic

    phase 2 small molecule completed

    1 trial

  31. ISIS 14803, peginterferon alfa, ribavirin

    IONIS PHARMACEUTICALS INC

    Hepatitis C, Chronic

    phase 2 small molecule completed

    1 trial

  32. ISIS 2503

    IONIS PHARMACEUTICALS INC

    Pancreatic Cancer

    phase 2 small molecule completed

    1 trial

  33. ISIS 301012

    IONIS PHARMACEUTICALS INC

    Hypercholesterolemia, Familial

    phase 2 small molecule completed

    1 trial

  34. ISIS 301012 or Placebo

    IONIS PHARMACEUTICALS INC

    Hypercholesterolemia, Familial

    phase 2 small molecule completed

    1 trial

  35. ISIS 301012 or Placebo

    IONIS PHARMACEUTICALS INC

    Hypercholesterolemia

    phase 2 small molecule completed

    2 trials

  36. ISIS 416858

    IONIS PHARMACEUTICALS INC

    End-stage Renal Disease (ESRD)

    phase 2 small molecule completed

    2 trials

  37. ISIS 443139 10 mg

    IONIS PHARMACEUTICALS INC

    Huntington's Disease

    phase 2 small molecule completed

    1 trial

  38. ISIS 678354

    IONIS PHARMACEUTICALS INC

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial

  39. ISIS 681257

    IONIS PHARMACEUTICALS INC

    Elevated Lipoprotein(a)

    phase 2 small molecule completed

    1 trial

  40. ISIS 702843

    IONIS PHARMACEUTICALS INC

    Polycythemia Vera

    phase 2 small molecule active

    1 trial

  41. ISIS 721744

    IONIS PHARMACEUTICALS INC

    Covid19

    phase 2 small molecule completed

    1 trial

  42. ISIS 721744

    IONIS PHARMACEUTICALS INC

    Hereditary Angioedema

    phase 2 small molecule active

    1 trial

  43. ISIS CRP Rx

    IONIS PHARMACEUTICALS INC

    Paroxysmal Atrial Fibrillation

    phase 2 small molecule completed

    1 trial

  44. ISIS CRP Rx or Placebo

    IONIS PHARMACEUTICALS INC

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  45. ISIS EIF4E Rx

    IONIS PHARMACEUTICALS INC

    Castrate-Resistant Prostate Cancer

    phase 2 small molecule completed

    1 trial

  46. ISIS EIF4E Rx

    IONIS PHARMACEUTICALS INC

    Non-small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial

  47. ISIS apoC-III Rx

    IONIS PHARMACEUTICALS INC

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial

  48. ISIS-APO(a)Rx

    IONIS PHARMACEUTICALS INC

    Elevated Lipoprotein(a)

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many pipeline programs does IONIS PHARMACEUTICALS have?

63 published programs are linked to this sponsor in our ClinicalTrials.gov index.

Is this the complete company pipeline?

This hub lists all published programs for the sponsor in our database. Partnered or out-licensed assets may appear under multiple companies.

Data attribution: Data sources · All pipeline programs

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