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Intelligence · Clinical Pipeline

IONIS PHARMACEUTICALS Pipeline

All ClinicalTrials.gov programs at IONIS PHARMACEUTICALS — phase, modality, and trial IDs.

Programs
32

Quick answer

IONIS PHARMACEUTICALS has 32 clinical development programs indexed from ClinicalTrials.gov, including phase, modality, indication text, and linked NCT identifiers.

  1. APOC-III-L-Rx

    IONIS PHARMACEUTICALS INC

    Elevated Triglycerides (TG)

    phase 1 small molecule completed

    1 trial

  2. AZD9150

    IONIS PHARMACEUTICALS INC

    Advanced Adult Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  3. BIIB094

    IONIS PHARMACEUTICALS INC

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  4. Eplontersen

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  5. Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer’s Disease (AD)

    IONIS PHARMACEUTICALS INC

    Alzheimer’s Disease in Individuals with Down Syndrome

    phase 1 other active

    1 trial

  6. ION251

    IONIS PHARMACEUTICALS INC

    Relapsed Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  7. ION269

    IONIS PHARMACEUTICALS INC

    Alzheimer Disease

    phase 1 small molecule terminated

    1 trial

  8. ION356

    IONIS PHARMACEUTICALS INC

    Pelizaeus-Merzbacher Disease

    phase 1 small molecule active

    1 trial

  9. ION464

    IONIS PHARMACEUTICALS INC

    Multiple System Atrophy

    phase 1 small molecule active

    1 trial

  10. ION537

    IONIS PHARMACEUTICALS INC

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  11. ION547

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  12. ION904

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  13. IONIS ANGPTL3-LRx

    IONIS PHARMACEUTICALS INC

    Hypertriglyceridemia

    phase 1 small molecule completed

    1 trial

  14. IONIS FXI-LRx

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  15. IONIS MAPTRx

    IONIS PHARMACEUTICALS INC

    Mild Alzheimer's Disease

    phase 1 small molecule completed

    1 trial

  16. IONIS TMPRSS6-Lrx

    IONIS PHARMACEUTICALS INC

    Thalassemia

    phase 1 small molecule completed

    1 trial

  17. IONIS-APO(a)-LRx

    IONIS PHARMACEUTICALS INC

    Elevated Lipoprotein(a)

    phase 1 small molecule completed

    1 trial

  18. IONIS-ENaCRx

    IONIS PHARMACEUTICALS INC

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  19. ISIS 325568

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  20. ISIS 333611

    IONIS PHARMACEUTICALS INC

    Familial Amyotrophic Lateral Sclerosis

    phase 1 small molecule completed

    1 trial

  21. ISIS 353512

    IONIS PHARMACEUTICALS INC

    Inflammatory Diseases

    phase 1 small molecule completed

    1 trial

  22. ISIS 388626

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  23. ISIS 681257

    IONIS PHARMACEUTICALS INC

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  24. Ionis AGT-LRx

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  25. Olezarsen

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  26. Placebo

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  27. Placebo

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  28. Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON)

    IONIS PHARMACEUTICALS INC

    Multiple System Atrophy

    phase 1 other active

    1 trial

  29. Volanesorsen

    IONIS PHARMACEUTICALS INC

    Abnormalities, Cardiovascular

    phase 1 small molecule completed

    1 trial

  30. mipomersen

    IONIS PHARMACEUTICALS INC

    Healthy Volunteer

    phase 1 small molecule completed

    3 trials

  31. mipomersen sodium

    IONIS PHARMACEUTICALS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  32. warfarin sodium

    IONIS PHARMACEUTICALS INC

    Healthy

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many pipeline programs does IONIS PHARMACEUTICALS have?

32 published programs are linked to this sponsor in our ClinicalTrials.gov index.

Is this the complete company pipeline?

This hub lists all published programs for the sponsor in our database. Partnered or out-licensed assets may appear under multiple companies.

Data attribution: Data sources · All pipeline programs

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