pharma · Small Cell Lung Cancer · Metastatic castration-resistant prostate cancer (mCRPC)
Amgen
Amgen trial registry — 99 ClinicalTrials.gov studies with program phase, status, and indication context.
Company details
- Status
- Public
- HQ
- One Amgen Center Drive, Thousand Oaks, CA 91320, US
- Founded
- 1980
- Employees
- 40,212
- Programs
- 96
- Drugs
- 124
- Patents
- 25
Amgen clinical trials
Registry index of 99 ClinicalTrials.gov studies linked to Amgen programs — each row shows trial ID, program name, phase, status, and indication.
Amgen trial registry — 99 ClinicalTrials.gov studies with program phase, status, and indication context.
Recent trial activity
Latest clinical program signals indexed for Amgen.
Trial registry
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2023-503433-21-00CTIS ↗
20190531
Behçet’s disease is a chronic, relapsing, multisystem inflammatory disorder of unknown etiology characterized by 4 major symptoms (oral aphthous ulcers, genital ulcers, skin lesions, and ocular lesions) and occasionally by 5 minor symptoms (arthritis, gastrointestinal ulcers, epididymitis, vascular lesions, and central nervous system [CNS] symptoms) (Cho, 2012). Juvenile idiopathic arthritis is a heterogeneous group of chronic inflammatory disorders that initially presents in children by the age of 16 years. It refers to arthritis of at least 6 weeks duration of unknown etiology that begins in children less than 16 years old. Juvenile idiopathic arthritis has an annual incidence of 2 to 20 cases per 100 000 population and a prevalence of 16 to 150 cases per 100 000 population. It is an autoimmune disorder marked by abnormalities of immune responses (Adelowo, 2010).
-
CTIS ↗ - 2023-503640-14-00CTIS ↗
20190360
Newly diagnosed Philadelphia-negative B-cell precursor Acute Lymphoblastic Leukemia in older adults
- 2023-503673-38-00CTIS ↗
Placebo for AMG 145, EVOLOCUMAB
Adults at high risk of cardiovascular events without prior MI or stroke.
-
CTIS ↗ -
CTIS ↗ - 2023-504364-42-00CTIS ↗
20220127
In Part 1, subjects with advanced MTAP-null solid tumors and, in Part 2, subjects with advanced MTAP-null Non Small-Cell Lung Cancer
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2023-505457-40-00CTIS ↗
20210096
Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer with FGFR2b overexpression
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2023-506136-32-00CTIS ↗
20180257
Relapsed or Refractory B cell Precursor Acute Lymphoblastic Leukemia (R/R B-ALL) and Minimal Residual Disease Positive (MRD+) B-ALL,
-
CTIS ↗ - 2023-506471-10-00CTIS ↗
20170724
Secondary hyperparathyroidism (SHPT) in pediatric patients with chronic kidney disease (CKD) in hemodialysis
-
CTIS ↗ -
CTIS ↗ - 2023-507149-27-00CTIS ↗
20170770
Chemotherapy-induced Thrombocytopenia in Adult subjects with Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer
-
CTIS ↗ - 2023-508214-42-00CTIS ↗
20190009
Previously treated locally advanced and unresectable or metastatic non-small cell lung cancer (NSCLC) with KRAS p.G12C mutation
-
CTIS ↗ - 2023-509047-26-00CTIS ↗
20220028
Dose Escalation: Non-small cell lung cancer (NSCLC), colorectal cancer (CRC), gastric cancer (GC), melanoma (MEL). Dose Confirmation: Lead Indication based on data from dose escalation. Dose Expansion: Tertiary Lymphoid Structure positive (TLS+) CRC, GC, and NSCLC.
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2024-511195-33-00CTIS ↗
20230223
Gastrointestinal tract, biliary tract, or pancreatic cancers with homozygous methylthioadenosine phosphorylase (MTAP)-deletion
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2024-513316-10-00CTIS ↗
A Phase 1b Study of AMG 757 in Subjects with Neuroendocrine Prostate Cancer
Adult subjects with de novo or treatment-emergent neuroendocrine prostate cancer
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2024-514304-14-00CTIS ↗
Comparison between ABP 234 and Keytruda® (Pembrolizumab)
Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2024-516654-22-00CTIS ↗
20230227
Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
-
CTIS ↗ - 2024-520050-38-00CTIS ↗
20240178
Extensive stage small cell lung cancer (ES-SCLC). Small-cell lung cancer, accounting for 10% to 15% of lung cancer (Rudin et al, 2015), is an aggressive lung cancer subtype with neuroendocrine differentiation and strongly associated with smoking (Koinis et al, 2016). It displays a distinct natural history characterized by a high growth fraction, rapid doubling time and early establishment of widespread metastatic lesions (Gustafsson et al, 2008). Around 70% of patients are diagnosed with ES-SCLC, presenting with distant metastasis or tumor or nodal volume that is too large to be encompassed in a tolerable radiation plan.
-
CTIS ↗ -
CTIS ↗ -
CTIS ↗ - 2025-520988-41-00CTIS ↗
Uplizna 100 mg concentrate for solution for infusion
Immunoglobulin G4 related Disease (IgG4-RD)
- 2025-520993-20-00CTIS ↗
Uplizna 100 mg concentrate for solution for infusion
Generalized Myasthenia Gravis
-
CTIS ↗ - 2025-521671-31-00CTIS ↗
Blinatumomab SC2
Relapsed/Refractory (R/R) and Minimal Residual Disease Positive (MRD+) B-Cell Precursor Acute Lymphoblastic Leukemia
-
CTIS ↗ - 2025-522703-14-00CTIS ↗
20230225
"Moderate to severe obstructive sleep apnea (OSA) in adults living with overweight or obesity"
- 2025-522888-15-00CTIS ↗
Phase 1b Study of Tarlatamab + ZL-1310 +/- Anti-PD-L1 in Small Cell Lung Cancer
Small Cell Lung Cancer
-
CTIS ↗ - 2025-524056-63-00CTIS ↗
20250004
microsatellite instability high/mismatch repair deficient (MSI-H/dMMR) solid tumors
-
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗ -
CT.gov ↗