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Intelligence · Clinical Pipeline

Phase III Pipeline Programs

Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Programs
5,427

Quick answer

NovaPharmaNews tracks 5,427 phase iii pharmaceutical pipeline programs from ClinicalTrials.gov. Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Top sponsors

Page 70 of 114

  1. Placebo

    Matinas BioPharma Holdings

    Severe Hypertriglyceridemia

    phase 3 small molecule terminated

    1 trial

  2. Placebo

    GlaxoSmithKline

    Infections, Papillomavirus

    phase 3 mab completed

    1 trial

  3. Placebo

    LEXICON PHARMACEUTICALS, INC.

    Type 1 Diabetes Mellitus

    phase 3 small molecule completed

    2 trials

  4. Placebo

    LEXICON PHARMACEUTICALS, INC.

    Type 2 Diabetes Mellitus

    phase 3 small molecule completed

    2 trials

  5. Placebo

    Blackmores Limited

    Parkinsons Disease (PD)

    phase 3 small molecule active

    1 trial

  6. Placebo

    Ono Pharmaceutical Co.,

    Chronic Sinusitis

    phase 3 small molecule completed

    1 trial

  7. Placebo

    Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

    Schizoaffective Disorder

    phase 3 small molecule completed

    1 trial

  8. Placebo

    Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

    Erectile Dysfunction

    phase 3 small molecule completed

    1 trial

  9. Placebo

    Tobira Therapeutics

    Nonalcoholic Steatohepatitis

    phase 3 small molecule terminated

    1 trial

  10. Placebo

    Regeneron UK Limited

    Colorectal Neoplasms

    phase 3 small molecule completed

    1 trial

  11. Placebo

    Sanofi Pasteur

    Osteoarthritis

    phase 3 small molecule completed

    1 trial

  12. Placebo

    Allergan Pharmaceuticals International Limited

    Gastroparesis

    phase 3 small molecule terminated

    3 trials

  13. Placebo

    Menarini Group

    Acute Pain

    phase 3 small molecule completed

    1 trial

  14. Placebo

    Ark Therapeutics

    Hyperphagia

    phase 3 small molecule on hold

    1 trial

  15. Placebo

    Sanofi Pasteur

    Colorectal Neoplasms

    phase 3 small molecule completed

    1 trial

  16. Placebo

    Pacira Ireland Limited

    Postoperative Pain

    phase 3 small molecule completed

    1 trial

  17. Placebo

    BioMarin Pharmaceutical Australia Pty Ltd

    Mucopolysaccharidosis VI

    phase 3 small molecule completed

    1 trial

  18. Placebo

    Hospital Authority, Hong Kong

    Congenital Heart Disease in Children

    phase 3 small molecule completed

    1 trial

  19. Placebo

    Acadia Pharmaceuticals B.V.

    Dementia-related Psychosis

    phase 3 small molecule completed

    1 trial

  20. Placebo

    Amgen

    Breast Cancer

    phase 3 small molecule terminated

    1 trial

  21. Placebo (Lisaftoclax), Lisaftoclax, Azacitidine Seacross 25 mg/mL powder for suspension for injection

    Lacuna Pharma Pty Ltd

    Newly Diagnosed Higher Risk Myelodysplastic Syndrome

    phase 3 small molecule active

    1 trial

  22. Placebo (Metoprolol succinate), Metoprololsuccinat STADA® 47,5 mg Retardtabletten, Aficamten, DOBUTAMINE , Placebo (Aficamten)

    Cytokinetics (Ireland) Limited

    Symptomatic Obstructive Hypertrophic Cardiomyopathy

    phase 3 small molecule active

    1 trial

  23. Placebo (Saline 0.9% (weight per volume; w/v)) for Pertuzumab, PERTUZUMAB, TRASTUZUMAB, PACLITAXEL, DS-8201a, DOCETAXEL

    AstraZeneca AB

    HER2-positive metastatic breast cancer

    phase 3 small molecule active

    1 trial

  24. Placebo (Vehicle) for investigational DFL24498, Isocyclosporin A, DEXAMETHASONE

    Dompe' Farmaceutici S.p.A.

    Atopic Keratoconjunctivitis

    phase 3 small molecule active

    1 trial

  25. Placebo (for alirocumab)

    Regeneron UK Limited

    Hypercholesterolemia

    phase 3 small molecule completed

    5 trials

  26. Placebo (inhalation powder capsules) containing 1 of 3 dosage strengths of TPIP (80 μg, 160 μg, or 320 μg), TREPROSTINIL PALMITIL INHALATION POWDER

    Insmed Limited

    Pulmonary Hypertension Associated with Interstitial Lung Disease

    phase 3 small molecule active

    1 trial

  27. Placebo (inhalation powder capsules) containing 1 of 4 dosage strengths of TPIP (80 μg, 160 μg, or 320 μg or 640 µg ), TREPROSTINIL PALMITIL INHALATION POWDER, TREPROSTINIL PALMITIL INHALATION POWDER, TREPROSTINIL PALMITIL INHALATION POWDER, TREPROSTINIL PALMITIL INHALATION POWDER

    Insmed Limited

    Pulmonary Hypertension Associated with Interstitial Lung Disease

    phase 3 small molecule active

    1 trial

  28. Placebo (ziltivekimab), ziltivekimab

    NovoThirteen

    Atherosclerotic cardiovascular disease, chronic kidney disease and systemic inflammation

    phase 3 small molecule active

    1 trial

  29. Placebo (ziltivekimab), ziltivekimab

    NovoThirteen

    Acute myocardial infarction

    phase 3 small molecule active

    1 trial

  30. Placebo + Placebo, cagrilintide semaglutide, cagrilintide semaglutide, cagrilintide semaglutide, cagrilintide semaglutide, cagrilintide semaglutide

    NovoThirteen

    Obesity

    phase 3 small molecule active

    1 trial

  31. Placebo - Film coated tablet for oral use, atrasentan

    Novartis Pharmaceuticals

    Immunoglobulin A Nephropathy (IgAN)

    phase 3 small molecule active

    1 trial

  32. Placebo - Staloral birch, oromucosal solution, STALORAL Birke 10 IR/ml und 300 IR/ml, Lösung zur Anwendung in der Mundhöhle, STALORAL Birke 300 IR/ml, Lösung zur Anwendung in der Mundhöhle

    Allergen

    Birch Pollen-induced Allergic Rhinoconjunctivitis

    phase 3 small molecule active

    1 trial

  33. Placebo - film-coated tablets, Lynparza 100 mg film-coated tablets, Lynparza 150 mg film-coated tablets

    AstraZeneca AB

    BRCA Mutated Advanced (FIGO Stage III-IV) Ovarian Cancer

    phase 3 small molecule active

    1 trial

  34. Placebo 0 mg hard gelatin capsule size 0, (placebo to LNP023 200 mg), IPTACOPAN

    Novartis Pharmaceuticals

    IgA Nephropathy

    phase 3 small molecule active

    1 trial

  35. Placebo 0 mg hard gelatin capsule size 0, (placebo to LNP023), IPTACOPAN

    Novartis Pharmaceuticals

    generalized Myasthenia Gravis

    phase 3 small molecule active

    1 trial

  36. Placebo 0 mg hard gelatin capsule size 1, (placebo to lnp023 100 mg), Placebo 0 mg hard gelatin capsule size 0, (placebo to lnp023 200 mg), IPTACOPAN HYDROCHLORIDE, IPTACOPAN

    Novartis Pharmaceuticals

    complement 3 glomerulopathy

    phase 3 small molecule active

    1 trial

  37. Placebo 0 mg/1 mL Solution for infusion/injection, VAY736

    Novartis Pharmaceuticals

    Autoimmune hepatitis

    phase 3 small molecule active

    1 trial

  38. Placebo 15mg Tablets, Placebo 6mg tablets, venglustat GZ402671 - SAR402671, venglustat GZ402671 - SAR402671

    Sanofi-aventis Healthcare Pty Ltd

    Fabry Disease

    phase 3 small molecule active

    1 trial

  39. Placebo ADCETRIS ( NaCl 0.9% 100 mL - Injection IV ), ADCETRIS 50 mg powder for concentrate for solution for infusion.

    Pari Pharma GmbH

    rare disease

    phase 3 small molecule active

    1 trial

  40. Placebo Colchicine 0.5 mg tablets, Colchicine Tiofarma 0,5 mg, tabletten

    Disc Medicine

    Aortic Valve Calcification, Inflammation, Calcification, Aortic Valve Disease, Cardiovascular Diseases, Aortic Valve Stenosis

    phase 3 small molecule active

    1 trial

  41. Placebo Film-coated tablet, JNJ-42847922

    Janssen-Cilag International N.V.

    Major Depressive Disorder with Insomnia Symptoms

    phase 3 small molecule active

    1 trial

  42. Placebo IRBESARTAN EG 150 mg, Irbesartan EG 150 mg comprimés pelliculés

    Pari Pharma GmbH

    Acute kidney injury

    phase 3 small molecule active

    1 trial

  43. Placebo Injection, Retatrutide, Retatrutide, Retatrutide, Retatrutide, Retatrutide

    Eli Lilly Co.

    Overweight, Obesity

    phase 3 small molecule active

    1 trial

  44. Placebo JNJ-78278343, Placebo JNJ-78278343, JNJ-78278343, JNJ-78278343

    Janssen-Cilag International N.V.

    Metastatic Castration-resistant Prostate Cancer (mCRPC)

    phase 3 small molecule active

    1 trial

  45. Placebo MDPI

    Teva Pharma GmbH

    Asthma

    phase 3 small molecule completed

    3 trials

  46. Placebo Mannitol 100mg pfi, ACEPURIN, poeder voor infusievloeistof 1g/100 ml

    Disc Medicine

    Brain injury in neonates with critical congenital heart disease requiring cardiac surgery with cardiopulmonary bypass.

    phase 3 small molecule active

    1 trial

  47. Placebo Matching Mitapivat

    Agios Netherlands B.V.

    Transfusion-dependent Alpha-Thalassemia

    phase 3 small molecule active

    1 trial

  48. Placebo Matching Mitapivat

    Agios Netherlands B.V.

    Non-Transfusion-dependent Alpha-Thalassemia

    phase 3 small molecule active

    1 trial

Frequently asked questions

How many Phase III pipeline programs are in the directory?

5,427 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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