🇺🇸 FDA

Intelligence · Clinical Pipeline

Phase III Pipeline Programs

Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Programs
5,427

Quick answer

NovaPharmaNews tracks 5,427 phase iii pharmaceutical pipeline programs from ClinicalTrials.gov. Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Top sponsors

Page 113 of 114

  1. tiotropium + olodaterol

    Boehringer Ingelheim

    Pulmonary Disease, Chronic Obstructive

    phase 3 small molecule completed

    1 trial

  2. tiotropium 5mcg/day

    Boehringer Ingelheim

    Asthma

    phase 3 small molecule completed

    1 trial

  3. tiotropium high dose

    Boehringer Ingelheim

    Asthma

    phase 3 small molecule completed

    1 trial

  4. tissue-of-origin (ORIGIN-PanCA○R) profiling

    Fudan University

    Cancer of Unknown Primary Site

    phase 3 gene therapy completed

    1 trial

  5. tividenofusp alfa

    Denali Therapeutics

    Mucopolysaccharidosis II

    phase 3 small molecule active

    3 trials

  6. tobacco abstinent contingent

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 3 other completed

    1 trial

  7. tocilizumab [RoActemra/Actemra]

    Hoffmann-La Roche

    Rheumatoid Arthritis

    phase 3 small molecule completed

    3 trials

  8. topiramate

    Ultragenyx UK Limited

    Lennox-Gastaut Syndrome

    phase 3 small molecule completed

    1 trial

  9. toripalimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Esophageal Cancer

    phase 3 small molecule active

    1 trial

  10. total knee arthroplasty

    Hospital Authority, Hong Kong

    Osteoarthritis, Knee

    phase 3 mab active

    1 trial

  11. training kit, CHF1535 pMDI 100/6, CHF5993 pMDI-US

    Chiesi Farmaceutici S.p.A

    Chronic obstructive pulmonary disease (COPD)

    phase 3 small molecule active

    1 trial

  12. trastuzumab

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 3 mab active

    1 trial

  13. treprostinil sodium

    United Therapeutics Europe Ltd

    Liver Transplant

    phase 3 small molecule terminated

    1 trial

  14. trifluridine/tipiracil

    Takeda

    Metastatic Oesogastric Adenocarcinoma

    phase 3 small molecule active

    1 trial

  15. trofosfamide, idarubicin, etoposide

    Solid Biosciences

    Soft Tissue Sarcoma

    phase 3 small molecule completed

    1 trial

  16. tulisokibart, Placebo to Subcutaneous or intravenous MK-7240 (Tulisokibart), tulisokibart

    Merck Sharp and Dohme

    Crohn’s Disease

    phase 3 small molecule active

    1 trial

  17. tulisokibart, tulisokibart, Placebo to MK-7240

    Merck Sharp and Dohme

    Ulcerative colitis

    phase 3 small molecule active

    1 trial

  18. turoctocog alfa pegol

    Novo Nordisk A/S

    Congenital Bleeding Disorder

    phase 3 small molecule completed

    2 trials

  19. ublituximab

    TG THERAPEUTICS, INC.

    relapsing multiple sclerosis

    phase 3 small molecule active

    1 trial

  20. ublituximab, DEXAMETHASONE, PARACETAMOL, GADOBUTROL, ublituximab placebo, DIPHENHYDRAMINE, CETIRIZINE, METHYLPREDNISOLONE

    TG THERAPEUTICS, INC.

    Relapsing multiple sclerosis

    phase 3 small molecule active

    1 trial

  21. urapidil

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stroke, Acute

    phase 3 small molecule completed

    1 trial

  22. valoctocogene roxaparvovec

    BioMarin Pharmaceutical Australia Pty Ltd

    Hemophilia A

    phase 3 mab active

    5 trials

  23. velaglucerase alfa

    Shire

    Gaucher Disease

    phase 3 mab completed

    1 trial

  24. velaglucerase alfa

    Takeda

    Gaucher Disease, Type 1

    phase 3 mab completed

    1 trial

  25. venetoclax

    The First People's Hospital of Lianyungang

    Acute Promyelocytic Leukemia

    phase 3 small molecule active

    1 trial

  26. vinflunine

    Pierre Fabre Medicament

    Breast Cancer

    phase 3 small molecule completed

    1 trial

  27. vitamin A supplementation (15,000 ug retinol equivalents or 50,000 IU)

    United Therapeutics Europe Ltd

    Mortality Through Six Months of Age

    phase 3 other completed

    1 trial

  28. vitamin D

    Takeda

    COVID-19

    phase 3 other completed

    1 trial

  29. voclosporin

    Aurinia Pharmaceuticals

    Renal Transplantation

    phase 3 small molecule terminated

    1 trial

  30. voclosporin

    Aurinia Pharmaceuticals

    Psoriasis

    phase 3 small molecule completed

    3 trials

  31. volanesorsen

    IONIS PHARMACEUTICALS INC

    Familial Partial Lipodystrophy

    phase 3 small molecule terminated

    1 trial

  32. volrustomig

    AstraZeneca

    Locally Advanced Head and Neck Squamous Cell Carcinoma

    phase 3 small molecule active

    1 trial

  33. volrustomig, KEYTRUDA 25 mg/mL concentrate for solution for infusion, Carboplatin Hikma 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung, Paclitaxel Bendalis 6 mg/ml Konzentrat zur Herstellung einer Infusionslösung, Pemetrexed Accord 25 mg/ml concentrate for solution for infusion, Mycofit, 250 mg, kapsułki twarde, Remsima 100 mg powder for concentrate for solution for infusion

    AstraZeneca AB

    Metastatic Non-Small Cell Lung Cancer (mNSCLC)

    phase 3 small molecule active

    1 trial

  34. von Willebrand factor (Recombinant)

    Takeda

    Von Willebrand Disease

    phase 3 mab completed

    1 trial

  35. vormatrogine

    Chongqing Precision Biotech Co., Ltd

    Epilepsy, Tonic-Clonic

    phase 3 small molecule active

    1 trial

  36. warfarin

    Bristol-Myers Squibb

    Atrial Fibrillation

    phase 3 small molecule completed

    1 trial

  37. warfarin

    Boehringer Ingelheim

    Atrial Fibrillation

    phase 3 small molecule completed

    1 trial

  38. whole-cell pertussis vaccine

    Ultragenyx UK Limited

    Pertussis

    phase 3 mab completed

    1 trial

  39. xevinapant, Xevinapant Placebo

    Merck Sharp and Dohme

    Resected squamous cell carcinoma of the head and neck

    phase 3 small molecule active

    1 trial

  40. zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Mantle Cell Lymphoma; Non-Hodgkin Lymphoma

    phase 3 small molecule active

    1 trial

  41. zeleciment basivarsen (DYNE-101)

    Dyne Therapeutics

    Myotonic Dystrophy Type 1 (DM1)

    phase 3 small molecule active

    1 trial

  42. zigakibart

    Novartis Pharmaceuticals

    Kidney Diseases

    phase 3 small molecule active

    1 trial

  43. zilganersen

    IONIS PHARMACEUTICALS INC

    Alexander Disease

    phase 3 small molecule active

    1 trial

  44. ziltivekimab, Placebo (ziltivekimab C)

    NovoThirteen

    Heart failure with mildly reduced or preserved ejection fraction and systemic inflammation

    phase 3 small molecule active

    1 trial

  45. ziltivekimab, Ziltivekimab

    NovoThirteen

    The medical condition we are investigating is type 1 AMI (STEMI and NSTEMI). Ziltivekimab is a human monoclonal antibody directed against the interleukin-6 (IL-6) ligand, and currently available clinical data support that ziltivekimab once-monthly reduces inflammation as measured by highsensitivity C-reactive protein (hs-CRP). With the recent proof-of-concept that hs-CRP reduction through inhibition of an upstream pathway leads to reduction in cardiovascular events, it is reasonable to expect that similar inhibition of IL-6 with ziltivekimab also reduces CV risk.The aim of the current study is to demonstrate the efficacy and safety of ziltivekimab in reducing the risk of major adverse cardiovascular events when initiated as early as possible in adult patients with ST-elevation and non-ST-elevation myocardial infarction

    phase 3 small molecule active

    1 trial

  46. zinc sulphate dietary supplement

    United Therapeutics Europe Ltd

    Nutrition

    phase 3 small molecule completed

    1 trial

  47. zodasiran Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Homozygous Familial Hypercholesterolemia

    phase 3 small molecule active

    1 trial

  48. zoledronic acid

    Novartis Pharmaceuticals

    Paget's Disease of Bone

    phase 3 small molecule completed

    1 trial

Frequently asked questions

How many Phase III pipeline programs are in the directory?

5,427 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.