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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Felzartamab, Saline Solution Basi 9 mg/ml solution for infusion

    Biogen

    Treatment of Late Isolated Microvascular Inflammation in Recipients of Kidney Transplants

    phase 2 small molecule active

    1 trial

  2. Fentanyl

    Teva Pharma GmbH

    Cancer

    phase 2 small molecule completed

    1 trial

  3. Fentanyl

    United Therapeutics Europe Ltd

    Healthy

    phase 2 small molecule completed

    1 trial

  4. Fentanyl Buccal Tablet

    Teva Pharma GmbH

    Advanced Cancers

    phase 2 small molecule completed

    1 trial

  5. Ferroquine SSR97193

    Sanofi Pasteur

    Plasmodium Falciparum Infection

    phase 2 small molecule terminated

    1 trial

  6. Fezolinetant

    Chinese University of Hong Kong

    Vasomotor Symptoms

    phase 2 small molecule active

    1 trial

  7. Fianlimab

    Regeneron UK Limited

    Advanced Melanoma

    phase 2 small molecule active

    1 trial

  8. Fianlimab

    Regeneron UK Limited

    Resectable Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  9. Fianlimab

    Regeneron UK Limited

    Advanced Renal Cell Carcinoma (aRCC)

    phase 2 small molecule active

    1 trial

  10. Fianlimab+cemiplimab

    Regeneron UK Limited

    Melanoma

    phase 2 small molecule active

    1 trial

  11. Fianlimab, LIBTAYO 350 mg concentrate for solution for infusion.

    CERO THERAPEUTICS HOLDINGS, INC.

    Pleural mesothelioma

    phase 2 small molecule active

    1 trial

  12. Fianlimab, LIBTAYO 350 mg concentrate for solution for infusion.

    Disc Medicine

    Metastatic solid tumors, these may include but are not limited to melanoma, non-small-cell lung carcinoma (NSCLC), cervical cancer, microsatellite instable (MSI)-high/deficient mismatch repair (dMMR) cancer, renal cell carcinoma (RCC), CSCC, urothelial cell carcer (UCC), small cell lung cancer (SCLC) and head and neck squamous cell carcinoma (HNSCC).

    phase 2 small molecule active

    1 trial

  13. Fibromun, Dacarbazine medac 1000 mg, powder for solution for infusion

    Philogen S.p.A.

    Unresectable and/or metastatic soft-tissue sarcoma after failure of at least two prior systemic therapy regimens.

    phase 2 small molecule active

    1 trial

  14. Fibromun, Darleukin

    Philogen S.p.A.

    Phase II, open label, multicentric, proof-of-principle basket trial in patients with malignant tumors of the skin amenable to intratumoral injection, and in a curative or neoadjuvant or palliative intention, including: • Basal cell carcinoma (BCC) • Cutaneous squamous cell carcinoma (cSCC) • Merkel cell carcinoma (MCC) • Keratoacanthoma (KA) • Malignant adnexal tumors of the skin (MATS) • Tumors from cutaneous T-cell lymphoma (CTCL) • Kaposi’s sarcoma (KS)

    phase 2 small molecule active

    1 trial

  15. Fibromun, Darleukin

    Philogen S.p.A.

    Patients with locally advanced Basal Cell Carcinoma (LaBCC) amenable to intratumoral injection, who have progressed or intolerant to systemic treatment.

    phase 2 small molecule active

    1 trial

  16. Fibromun, Darleukin

    Philogen S.p.A.

    Cutaneous Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  17. Fibromun, Temozolomide SUN 100 mg hard capsules

    Philogen S.p.A.

    Glioblastoma

    phase 2 small molecule active

    1 trial

  18. Ficerafusp alfa

    Bicara Therapeutics

    Head and Neck Squamous Cell Carcinoma (HNSCC)

    phase 2 small molecule active

    1 trial

  19. Ficerafusp alfa

    Bicara Therapeutics

    Squamous Cell Carcinoma of Head and Neck (SCCHN)

    phase 2 small molecule active

    1 trial

  20. Filgotinib

    Lakefront Biotherapeutics NV

    Small Bowel Crohn's Disease

    phase 2 small molecule completed

    1 trial

  21. Filgotinib

    Lakefront Biotherapeutics NV

    Fistulizing Crohn's Disease

    phase 2 small molecule completed

    1 trial

  22. Filgotinib

    Lakefront Biotherapeutics NV

    Noninfectious Uveitis

    phase 2 small molecule terminated

    1 trial

  23. Filgotinib

    Lakefront Biotherapeutics NV

    Inflammatory Bowel Disease

    phase 2 small molecule terminated

    1 trial

  24. Film-coated placebo to match estetrol monohydrate (E4) 20mg tablet

    Estetra SPRL

    postmenopausal women with vasomotor menopausal symptoms

    phase 2 small molecule active

    1 trial

  25. Film-coated tablet, Major Ingredients Mannitol, microcrystalline cellulose, magnesium stearate, polyvinyl alcohol, macrogol, titanium dioxide and talc, Fipaxalparant

    Elan Pharma International

    Diffuse Cutaneous Systemic Sclerosis

    phase 2 small molecule active

    1 trial

  26. Fipaxalparant

    Elan Pharma International

    Diffuse Cutaneous Systemic Sclerosis

    phase 2 small molecule active

    1 trial

  27. Fipaxalparant, Film-coated tablet, Major Ingredients Mannitol, microcrystalline cellulose, magnesium stearate, polyvinyl alcohol, macrogol, titanium dioxide and talc

    Elan Pharma International

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial

  28. First-line Chemotherapy With Temozolomide Alone for Non-enhancing Adult Brainstem Gliomas, With a Diffuse Subtype and Showing Clinical and/or Radiological Infiltrative Pattern of Progression (TEMOTRAD01)

    Pari Pharma GmbH

    Adults with non-contrast-enhancing diffuse brainstem gliomas with non-threatening infiltrative clinical and/or radiological progression, Adult brain stem gliomas

    phase 2 other active

    1 trial

  29. First-line Cohort

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial

  30. Fisetin

    United Therapeutics Europe Ltd

    Femoroacetabular Impingement

    phase 2 small molecule active

    1 trial

  31. Fixed dose combination Ciprofloxacin/Celecoxib

    NeuroSense Therapeutics

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule completed

    1 trial

  32. Florquinitau F-18, Sodium Chloride, PRX005

    Bristol-Myers Squibb Australia Pty Ltd

    Early Alzheimer’s Disease

    phase 2 small molecule active

    1 trial

  33. Flortaucipir, Placebo to match LY3372689

    Eli Lilly Co.

    Alzheimer Disease

    phase 2 small molecule active

    1 trial

  34. Fluciclovine F18

    Telix Innovations

    Prostate Adenocarcinoma

    phase 2 small molecule active

    1 trial

  35. Fludarabina Accord 25 mg/ml concentrado para solución inyectable y para perfusión., HSP-CAR30, Levact 2,5 mg/ml poudre pour solution à diluer pour perfusion, RoActemra 20 mg/mL concentrate for solution for infusion, Genoxal 200 mg polvo para solución inyectable y para perfusión

    The George Institute

    Refractary or relapse non-Hodgkin T CD30+ lymphoma., Refractary or relapse Hodgkin T CD30+ lymphoma

    phase 2 small molecule active

    1 trial

  36. Fludarabine

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia, Adult

    phase 2 small molecule terminated

    1 trial

  37. Fludarabine

    Jazz Pharmaceuticals Ireland Limited

    Hematologic Malignancy

    phase 2 small molecule terminated

    1 trial

  38. Fludarabine (FLU)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Aplastic Anemia Idiopathic

    phase 2 small molecule active

    1 trial

  39. Fludarabine Teva 25 mg/ml solution à diluer pour injection ou perfusion, Fludarabine phosphate 25 mg/ml Concentrate for Solution for Injection or Infusion, LN-145, Proleukin 18 x 106 IE Poeder voor oplossing voor injectie of infusie, Cyclophosphamide Injection 1 g., Fludarabine 50mg Powder For Solution For Injection Or Infusion, Endoxan, Флударабин Актавис 25 mg/ml концентрат за инжекционен или инфузионен разтвор, Fludarabinefosfaat – PCH 25 mg/ml, concentraat voor oplossing voor injectie/infusie, FLUDARAB

    Iovance Biotherapeutics B.V.

    Metastatic Non-Small-Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  40. Fludrocortisone 100 mcg daily

    Chinese University of Hong Kong

    Sepsis

    phase 2 small molecule active

    1 trial

  41. Flumazenil

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 small molecule completed

    1 trial

  42. Fluocinolone Acetonide

    ANI PHARMACEUTICALS INC

    Age-Related Macular Degeneration

    phase 2 small molecule terminated

    1 trial

  43. Fluocinolone Acetonide

    ANI PHARMACEUTICALS INC

    Macular Edema

    phase 2 small molecule terminated

    1 trial

  44. Fluorodopa F 18

    BRIGHT MINDS BIOSCIENCES INC.

    Malignant Brain Neoplasm

    phase 2 small molecule active

    1 trial

  45. Fluorouracil

    United Therapeutics Europe Ltd

    Clinical Stage II Esophageal Adenocarcinoma AJCC v8

    phase 2 small molecule active

    1 trial

  46. Fluorouracil

    United Therapeutics Europe Ltd

    Metastatic Biliary Tract Carcinoma

    phase 2 small molecule active

    1 trial

  47. Fluorouracil

    Arcus Biosciences

    Borderline Resectable Pancreatic Adenocarcinoma

    phase 2 small molecule active

    1 trial

  48. Fluorouracil 50mg/ml Injection., FOLINIC ACID, Eftozanermin alfa, Telisotuzumab adizutecan, Oxaliplatin 5 mg/ml concentrate for solution for infusion

    AbbVie Deutschland GmbH & Co. KG

    Adenocarcinoma of the gastroesophageal junction

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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