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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Cinryze 500 IU powder and solvent for solution for injection, Saline Solution Basi 9 mg/ml solution for infusion

    Disc Medicine

    Traumatic Brain Injury

    phase 2 small molecule active

    1 trial

  2. Ciprofloxacin

    United Therapeutics Europe Ltd

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  3. Cisplatin

    Ultragenyx UK Limited

    Squamous Cell Carcinoma of the Anus

    phase 2 small molecule active

    1 trial

  4. Cisplatin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cervical Cancer

    phase 2 small molecule active

    1 trial

  5. Cisplatin Accord Healthcare 1 mg/ml concentraat voor oplossing voor infusie, Carboplatin Accord Healthcare 10 mg/ml concentraat voor oplossing voor infusie

    Disc Medicine

    Vulvar cancer

    phase 2 small molecule active

    1 trial

  6. Cisplatin and Doxorubicin

    Chinese University of Hong Kong

    Gastric Cancer Peritoneal Metastases

    phase 2 small molecule active

    1 trial

  7. Cisplatin+Albumin-bound paclitaxel (1 cycle) and PD-1 monoclonal antibody+Cisplatin+Albumin-bound paclitaxel (2 cycles)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Uterine Cervical Neoplasm

    phase 2 small molecule active

    1 trial

  8. Cisplatin+Capecitabine+Sintilimab

    The First People's Hospital of Lianyungang

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  9. Cisplatino Accord Healthcare Italia 1 mg/ml concentrato per soluzione per infusione, DOXORUBICINA ACCORD HEALTHCARE ITALIA 2 mg/ml concentrato per soluzione per infusione

    Sana Biotechnology

    Pleural carcinosis

    phase 2 small molecule active

    1 trial

  10. Citalopram

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    3 trials

  11. Citanest® Dental Octapressin 30 mg/ml + 0,03 IE/ml, Xylocain ®Dental adrenalin 20 mg/ml + 12,5 mikrog/ml Injeksjonsvæske, oppløsning i sylindretter

    Lacuna Pharma Pty Ltd

    Subjects having local anesthesia for dental procedures.

    phase 2 small molecule active

    1 trial

  12. Cizutamig

    Lacuna Pharma Pty Ltd

    Severe, treatment refractory primary Sjögren’s disease (pSjD), Severe, treatment refractory idiopathic inflammatory myopathy (IIM), Severe, treatment refractory systemic sclerosis (SSc), Severe, treatment-refractory, seropositive (anti-citrullinated protein antibody (ACPA) and/or rheumatoid factor positive) rheumatoid arthritis (RA)

    phase 2 small molecule active

    1 trial

  13. Clarithromycin

    Takeda

    Myeloma

    phase 2 small molecule active

    1 trial

  14. Claseprubart

    Dianthus Therapeutics, Inc. /DE/

    Multifocal Motor Neuropathy

    phase 2 small molecule active

    1 trial

  15. Clifutinib Besylate

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Acute Myeloid Leukemia, Adult

    phase 2 small molecule active

    1 trial

  16. Clinical Trial Using Humanized CART Directed Against BCMA (ARI0002h) in Patients With Relapsed/​Refractory Multiple Myeloma to Proteasome Inhibitors, Immunomodulators and Anti-CD38 Antibody

    The George Institute

    Multiple Myeloma

    phase 2 other active

    1 trial

  17. Clobetasol Propionate

    United Therapeutics Europe Ltd

    Colon Adenocarcinoma

    phase 2 small molecule completed

    1 trial

  18. Clonazepam

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use Disorder

    phase 2 small molecule completed

    1 trial

  19. Clonazepam

    BRIGHT MINDS BIOSCIENCES INC.

    REM Sleep Behavior Disorder

    phase 2 small molecule completed

    1 trial

  20. Clonazepam

    Jazz Pharmaceuticals Ireland Limited

    Epilepsy

    phase 2 small molecule completed

    1 trial

  21. Clonazepam Orally Disintegrating Tablets, USP, Clonazepam Orally Disintegrating Tablets, USP, JNJ-64407564, JNJ-64407564, Clonazepam Orally Disintegrating Tablets, USP, Pregabalin-ratiopharm® 25 mg Hartkapseln, Pregabalin-ratiopharm® 50 mg Hartkapseln, Clonazepam Orally Disintegrating Tablets, USP, DEXAMETHASONE ELIXIR, USP, Clonazepam Orally Disintegrating Tablets, USP, Clonazepam Orally Disintegrating Tablets, USP

    Janssen-Cilag International N.V.

    multiple myeloma

    phase 2 small molecule active

    1 trial

  22. Clonidine

    Grace Therapeutics

    Pregnancy Related

    phase 2 small molecule completed

    1 trial

  23. Clonidine

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 2 small molecule completed

    1 trial

  24. Clostridium Butyricum Tablets

    The First People's Hospital of Lianyungang

    Bladder (Urothelial, Transitional Cell) Cancer

    phase 2 small molecule active

    1 trial

  25. Coagulation Factor IX variant

    CATALYST PHARMACEUTICALS, INC.

    Hemophilia B

    phase 2 mab completed

    1 trial

  26. Coagulation Factor VIIa variant

    CATALYST PHARMACEUTICALS, INC.

    Hemophilia A With Inhibitor

    phase 2 mab completed

    1 trial

  27. Coagulation Factor VIIa variant

    CATALYST PHARMACEUTICALS, INC.

    Factor VII Deficiency

    phase 2 mab terminated

    1 trial

  28. Cobimetinib

    Hoffmann-La Roche

    Solid Tumors

    phase 2 small molecule completed

    1 trial

  29. Coenzyme Q10

    United Therapeutics Europe Ltd

    Charcot Marie Tooth Disease

    phase 2 small molecule completed

    1 trial

  30. Cognitive Behavioral Intervention

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 other completed

    1 trial

  31. Cognitive Behavioral Therapy (CBT)

    BRIGHT MINDS BIOSCIENCES INC.

    Stress Disorders, Post Traumatic

    phase 2 other completed

    1 trial

  32. Cohort A: ORMD-0801

    ORAMED PHARMACEUTICALS INC.

    T2DM (Type 2 Diabetes Mellitus)

    phase 2 small molecule completed

    1 trial

  33. Cohort A: vilobelimab

    Edesa Biotech

    Acute Respiratory Distress Syndrome (ARDS)

    phase 2 small molecule active

    2 trials

  34. Cohort B: paridiprubart

    Edesa Biotech

    Acute Respiratory Distress Syndrome (ARDS)

    phase 2 small molecule active

    1 trial

  35. Cohort C: bevacizumab

    Edesa Biotech

    Acute Respiratory Distress Syndrome (ARDS)

    phase 2 small molecule active

    1 trial

  36. Colchicine

    Ultragenyx UK Limited

    Primary Cutaneous Vasculitis

    phase 2 small molecule active

    1 trial

  37. Colchicine 0.5mg

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cerebral Amyloid Angiopathy

    phase 2 small molecule active

    1 trial

  38. Colchicine, 0.6 mg PO BID

    Takeda

    Atrial Fibrillation

    phase 2 small molecule completed

    1 trial

  39. Cold Stored Platelets (CSP)

    United Therapeutics Europe Ltd

    Trauma

    phase 2 mab completed

    1 trial

  40. Cold stored platelets in 100% plasma stored for 10-14 days

    United Therapeutics Europe Ltd

    Hemorrhage

    phase 2 mab active

    1 trial

  41. Colesevelam hydrochloride-MMX® modified-release placebo tablets, Colesevelam hydrochloride-MMX® 900 mg modified-release tablets

    Cosmo Technologies Ltd

    bile acid diarrhoea (BAD)

    phase 2 small molecule active

    1 trial

  42. Colon originated: Neostigmin, Colonoscopy decompression, Surgery

    Chinese University of Hong Kong

    Acute Lower Gastrointestinal Dysfunction

    phase 2 other active

    1 trial

  43. Colonoscopy with enhanced dye

    Cardiff Oncology

    Colorectal Cancer

    phase 2 other completed

    1 trial

  44. Columvi 10 mg concentrate for solution for infusion, Gazyvaro 1,000 mg concentrate for solution for infusion., Breyanzi 1.1-70 × 106 cells/mL / 1.1-70 × 106 cells/mL dispersion for infusion, YESCARTA 0.4 – 2 x 10e8 cells dispersion for infusion

    The George Institute

    relapsed/refractory Large B-Cell Lymphoma

    phase 2 small molecule active

    1 trial

  45. Columvi 10 mg concentrate for solution for infusion, Gazyvaro 1,000 mg concentrate for solution for infusion., Maplirpacept

    Pfizer Australia Pty Ltd

    Relapsed/Refractory Diffuse Large B Cell Lymphoma

    phase 2 small molecule active

    1 trial

  46. Columvi 10 mg concentrate for solution for infusion, Glofitamab, Gazyvaro 1,000 mg concentrate for solution for infusion., RoActemra 20 mg/mL concentrate for solution for infusion

    Hoffmann-La Roche

    Relapsed/refractory B-cell non-Hodgkin’s lymphoma (r/r NHL)

    phase 2 small molecule active

    1 trial

  47. Combination of Bortezomib, Fludarabine and Cyclophosphamide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Mantle Cell Lymphoma Recurrent

    phase 2 small molecule active

    1 trial

  48. Combination of MK3475 with Metronomic CP

    Lxo Ireland Designated Activity Company

    Sarcoma

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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