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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. TVB-2640

    Sagimet Biosciences

    KRAS Gene Mutation

    phase 2 small molecule active

    1 trial

  2. TVB-2640

    Sagimet Biosciences

    Metabolic Dysfunction-assocated Steatohepatitis/ Nonalcoholic Fatty Liver Disease

    phase 2 small molecule completed

    1 trial

  3. TVB-2640 25 mg (US)

    Sagimet Biosciences

    MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)

    phase 2 small molecule completed

    1 trial

  4. TX200-TR101

    SANGAMO THERAPEUTICS, INC

    Kidney Transplant Rejection

    phase 2 mab active

    1 trial

  5. TX200-TR101

    SANGAMO THERAPEUTICS, INC

    Prophylaxis against renal transplant rejection

    phase 2 small molecule active

    1 trial

  6. TYRA-300

    Tyra Biosciences

    Locally Advanced Urothelial Carcinoma

    phase 2 small molecule active

    1 trial

  7. TYRA-300 0.125 mg/kg

    Tyra Biosciences

    Achondroplasia

    phase 2 small molecule active

    1 trial

  8. TYRA-300 60mg

    Tyra Biosciences

    Low-grade NMIBC

    phase 2 small molecule active

    1 trial

  9. Tabelecleucel

    Evidence Based Cataract Study Group

    Nasopharyngeal Carcinoma

    phase 2 mab terminated

    1 trial

  10. Tablets are oval, biconvex, plain and white to off white, Placebo for GSK4011499 Tablets are tablets for oral administration. Tablets are oval, biconvex, plain, and white to off white.

    ViiV Healthcare Pty Ltd

    HIV Infections

    phase 2 small molecule active

    1 trial

  11. Tacrolimus

    Astellas Pharma Inc

    Bone Marrow Transplantation

    phase 2 small molecule completed

    1 trial

  12. Tacrolimus ointment

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Tacrolimus, Kaposiform Hemangioendothelioma, Tufted Angioma

    phase 2 small molecule active

    1 trial

  13. Tafenoquine

    60 DEGREES PHARMACEUTICALS, INC.

    Babesiosis

    phase 2 small molecule active

    1 trial

  14. Tafenoquine

    60 DEGREES PHARMACEUTICALS, INC.

    Healthy Volunteers

    phase 2 small molecule completed

    1 trial

  15. Tafenoquine 100mg

    60 DEGREES PHARMACEUTICALS, INC.

    Chronic Babesiosis

    phase 2 small molecule active

    1 trial

  16. Tafenoquine Oral Tablet

    60 DEGREES PHARMACEUTICALS, INC.

    COVID 19 Disease

    phase 2 small molecule completed

    1 trial

  17. Tagraxofusp

    Stemline Therapeutics B.V.

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial

  18. Tak-228 & Tak-117

    Takeda

    Triple Negative Breast Cancer

    phase 2 small molecule completed

    1 trial

  19. Takeda's Tetravalent Dengue Vaccine Candidate (TDV)

    Takeda

    Dengue Fever

    phase 2 mab completed

    2 trials

  20. Talampanel

    Teva Pharma GmbH

    Epilepsy

    phase 2 small molecule completed

    1 trial

  21. Talampanel

    Teva Pharma GmbH

    ALS

    phase 2 small molecule completed

    1 trial

  22. Talampanel

    Teva Pharma GmbH

    Glioblastoma Multiforme

    phase 2 small molecule terminated

    2 trials

  23. Talampanel

    Teva Pharma GmbH

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule terminated

    1 trial

  24. Talazoparib Tosylate

    BioMarin Pharmaceutical Australia Pty Ltd

    Advanced Breast Cancer

    phase 2 small molecule completed

    1 trial

  25. Tangweian Recipe

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Diabetic Gastroenteropathy

    phase 2 small molecule active

    1 trial

  26. Taodan Granules

    Universal Integrated

    Psoriasis Vulgaris

    phase 2 small molecule active

    1 trial

  27. Target-controlled naloxone-infusion

    BRIGHT MINDS BIOSCIENCES INC.

    Central Nervous System Sensitization

    phase 2 small molecule completed

    1 trial

  28. Tarlatamab

    Amgen

    Relapsed/Refractory Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  29. Tarlatamab, TARLATAMAB, Tarlatamab, SILTUXIMAB

    Amgen

    Relapsed/Refractory Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  30. Tarlatamab, Tarlatamab

    The George Institute

    Metastaic small cell lung cancer (SCLC) and other poorly differentitated neuroendocrine carcinomas (NECs)

    phase 2 small molecule active

    1 trial

  31. Tarlatamab, Tarlatamab

    Partner Therapeutics Limited

    Patients with pretreated extensive-stage small cell lung cancer (ES-SCLC) and ECOG PS 2

    phase 2 small molecule active

    1 trial

  32. Tarperprumig Placebo, Tarperprumig

    Alexion Europe SAS

    Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis

    phase 2 small molecule active

    1 trial

  33. Tas-102(Suyuan) combined with bevacizumab

    The First People's Hospital of Lianyungang

    Colorectal Cancer

    phase 2 small molecule active

    1 trial

  34. Tasigna 150 mg hard capsules, Scemblix 40 mg film-coated tablets

    Fondazione Telethon ETS

    BCR-ABL1+ Chronic Myeloid Leukemia

    phase 2 small molecule active

    1 trial

  35. Tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Jet Lag Disorder

    phase 2 small molecule completed

    1 trial

  36. Taxotere

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 2 small molecule terminated

    1 trial

  37. Tazemetostat

    Eisai Co.,

    Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

    phase 2 small molecule completed

    1 trial

  38. Tebapivat

    Agios Netherlands B.V.

    Myelodysplastic Syndromes

    phase 2 small molecule active

    1 trial

  39. Tebapivat

    Agios Netherlands B.V.

    Sickle Cell Disease

    phase 2 small molecule active

    1 trial

  40. Tecentriq 1 200 mg concentrate for solution for infusion

    The George Institute

    Locally advanced cervical cancer

    phase 2 small molecule active

    1 trial

  41. Tecentriq 1 200 mg concentrate for solution for infusion

    Ningbo Cancer Hospital

    Muscle-invasive bladder cancer

    phase 2 small molecule active

    1 trial

  42. Tecentriq 1 200 mg concentrate for solution for infusion

    Tour Hekla

    Muscle-invasive bladder cancer

    phase 2 small molecule active

    1 trial

  43. Tecentriq 1 200 mg concentrate for solution for infusion

    Wuhan Createrna Science and Technology Co., Ltd

    Limited disease small-cell lung cancer

    phase 2 small molecule active

    1 trial

  44. Tecentriq 1 200 mg concentrate for solution for infusion

    Disc Medicine

    (Diffuse) Large B-cell Lymphoma

    phase 2 small molecule active

    1 trial

  45. Tecentriq 1 200 mg concentrate for solution for infusion, Avastin 25 mg/ml concentrate for solution for infusion.

    The George Institute

    Patients with resectable hepatocellular carcinoma (amenable R0 resection) at high risk of recurrence.

    phase 2 small molecule active

    1 trial

  46. Tecentriq 1 200 mg concentrate for solution for infusion, EIK1001 solution for injection 1.0 mg/mL free base equivalent

    The George Institute

    Adult participants with metastatic (advanced) solid tumors.

    phase 2 small molecule active

    1 trial

  47. Tecentriq 1 200 mg concentrate for solution for infusion, OXALIPLATINE HOSPIRA 5 mg/ml, solution à diluer pour perfusion, Avastin 25 mg/ml concentrate for solution for infusion., CAPECITABINE VIATRIS 500 mg, comprimé pelliculé

    CERO THERAPEUTICS HOLDINGS, INC.

    microsatellite stable (MSS) colorectal cancer with liver-dominant metastasis

    phase 2 small molecule active

    1 trial

  48. Tecentriq 1 200 mg concentrate for solution for infusion, Pulmocis 2 mg trousse pour préparation radiopharmaceutique, Avastin 25 mg/ml concentrate for solution for infusion.

    The George Institute

    Non resectable Hepatocellular carcinoma (HCC)

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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