Friday, July 10, 2026

Intelligence · Clinical pipeline

Oncology · Phase II

Oncology programs at Phase II — ClinicalTrials.gov pipeline intelligence.

Programs 2,637

Quick answer

Oncology Phase II programs: NovaPharmaNews indexes 2,637 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

Top sponsors

Pipeline programs

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  1. WBRT

    United Therapeutics Europe Ltd

    Bladder Cancer

    phase 2 other active

    1 trial
  2. WO39608

    Hoffmann-La Roche

    Pancreatic ductal adenocarcinoma (PDAC)

    phase 2 small molecule active

    1 trial
  3. WO42178

    Hoffmann-La Roche

    Persistent or Recurrent Rare Epithelial Ovarian Tumors

    phase 2 small molecule active

    1 trial
  4. WO46063

    Hoffmann-La Roche

    Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha gene (PIK3CA)-Mutated, hormone receptor-positive (HR-Positive), human epidermal growth factor receptor 2 (HER2)-Negative Locally Advanced or Metastatic Breast Cancer

    phase 2 small molecule active

    1 trial
  5. WSD0922-FU, WSD0922-FU

    Alphapharm Pty Ltd

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  6. WTX-330

    Werewolf Therapeutics

    Advanced or Metastatic Solid Tumors

    phase 2 small molecule active

    2 trials
  7. Watchful waiting, RO7198457 (autogene cevumeran)

    BioNTech SE

    Stage II/Stage III rectal cancer or Stage II (high risk)/Stage III colon cancer

    phase 2 small molecule active

    1 trial
  8. Will receive HH-009 injection 20 mg/kg, Q3W

    Huahui Health

    Advanced or Unresectable Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial
  9. X4P-001

    X4 Pharmaceuticals, Inc

    Clear Cell Renal Cell Carcinoma

    phase 2 small molecule completed

    2 trials
  10. XB2001 or Placebo

    XBiotech Germany GmbH

    Pancreatic Cancer

    phase 2 mab active

    1 trial
  11. XELOX combined with Fruquintinib and Sintilimab

    The First People's Hospital of Lianyungang

    Gastric Cancer/Gastroesophageal Junction Adenocarcinoma

    phase 2 small molecule active

    1 trial
  12. XMDYYYXYK-04

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  13. XTX202

    Xilio Therapeutics

    Advanced Solid Tumor

    phase 2 small molecule completed

    1 trial
  14. XTX301

    Xilio Therapeutics

    Advanced Solid Tumor

    phase 2 small molecule active

    1 trial
  15. Xospata 40 mg film-coated tablets

    Fondazione Telethon ETS

    newly diagnosed non-M3 FLT3-positive acute myeloid leukemia

    phase 2 small molecule active

    1 trial
  16. YERVOY for castration-resistant prostate c…

    Disc Medicine

    castration-resistant prostate cancer

    phase 2 small molecule active

    1 trial
  17. Z650

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule completed

    1 trial
  18. ZD6474

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 2 small molecule completed

    2 trials
  19. ZG005

    Suzhou Zelgen Biopharmaceuticals Co.,Ltd

    Biliary Tract Carcinoma

    phase 2 small molecule active

    1 trial
  20. ZIMBERELIMAB

    Arcus Biosciences

    Pancreatic Cancer

    phase 2 small molecule on hold

    1 trial
  21. ZIO-201

    Alaunos Therapeutics

    Advanced Sarcoma

    phase 2 small molecule completed

    1 trial
  22. ZIV-Aflibercept

    Regeneron UK Limited

    Metastatic Uveal Melanoma

    phase 2 small molecule active

    1 trial
  23. ZN-d5 ZN-c3

    Zentalis Pharmaceuticals

    Acute Myeloid Leukemia (AML)

    phase 2 small molecule terminated

    1 trial
  24. ZW25 (Zanidatamab)

    Jazz Pharmaceuticals Ireland Limited

    HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

    phase 2 small molecule completed

    1 trial
  25. ZW25 (Zanidatamab)

    BEONE MEDICINES AUS PTY LTD

    HER2-amplified Biliary Tract Cancers

    phase 2 small molecule completed

    1 trial
  26. ZW25 (Zanidatamab)

    Jazz Pharmaceuticals Ireland Limited

    HER2+/HR+ Breast Cancer

    phase 2 small molecule completed

    1 trial
  27. ZWI-ZW25-202

    Jazz Pharmaceuticals Ireland Limited

    Breast cancer patients including those with locally advanced (unresectable) or metastatic HER2-positive, HR-positive breast cancer

    phase 2 small molecule active

    1 trial
  28. ZZ-IT-ICI-HCC 1line-023

    Second Affiliated Hospital of Soochow University

    Liver Cancer

    phase 2 small molecule active

    1 trial
  29. Zanidatamab

    Jazz Pharmaceuticals Ireland Limited

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  30. Zanidatamab

    Jazz Pharmaceuticals Ireland Limited

    HER2-positive Breast Cancer

    phase 2 small molecule active

    1 trial
  31. Zanidatamab

    Jazz Pharmaceuticals Ireland Limited

    Breast Cancer

    phase 2 small molecule active

    1 trial
  32. Zanidatamab

    Jazz Pharmaceuticals Ireland Limited

    Gastroesophageal Adenocarcinoma

    phase 2 small molecule active

    1 trial
  33. Zanidatamab

    ALX ONCOLOGY HOLDINGS INC

    HER2-expressing Cancers

    phase 2 small molecule completed

    1 trial
  34. Zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Relapsed/Refractory Follicular Non-Hodgkin Lymphoma

    phase 2 small molecule completed

    1 trial
  35. Zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial
  36. Zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Follicular Lymphoma

    phase 2 small molecule active

    1 trial
  37. Zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Diffuse Large B-cell Lymphoma (DLBCL)

    phase 2 small molecule active

    1 trial
  38. Zanubrutinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial
  39. Zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

    phase 2 small molecule completed

    1 trial
  40. Zanubrutinib

    The First People's Hospital of Lianyungang

    Non Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial
  41. Zanubrutinib

    The First People's Hospital of Lianyungang

    Chronic Lymphocytic Leukemia

    phase 2 small molecule active

    1 trial
  42. Zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Relapsed Diffuse Large B-cell Lymphoma

    phase 2 small molecule completed

    1 trial
  43. Zanubrutinib

    BEONE MEDICINES AUS PTY LTD

    Chronic Lymphocytic Leukemia (CLL)

    phase 2 small molecule active

    1 trial
  44. Zanubrutinib+Rituximab+Lenalidomide

    The First People's Hospital of Lianyungang

    Diffuse Large B Cell Lymphoma

    phase 2 small molecule active

    1 trial
  45. Zelenectide Pevedotin, BT8009

    BICYCLE THERAPEUTICS

    Advanced or Metastatic Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  46. Zentalis

    Zentalis Pharmaceuticals

    Advanced Pancreatic Adenocarcinoma

    phase 2 small molecule active

    1 trial
  47. Ziftomenib

    Kura Oncology

    Advanced Malignant Neoplasm

    phase 2 small molecule active

    1 trial
  48. Ziftomenib, Ziftomenib

    Kura Oncology

    Relapsed and/or refractory Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many oncology Phase II programs exist?

2,637 programs match both the therapeutic area and stage filters in our published index.