Oncology · Phase I

Top sponsors

• Chinese Academy of 70 programs
• First People's Hospital 62 programs
• Takeda 49 programs
• United Therapeutics Europe 41 programs
• BEONE MEDICINES AUS 40 programs
• Regeneron UK 34 programs
• Anaxis Pharma 31 programs
• Chongqing Precision Biotech 27 programs
• Janssen-Cilag International N.V 27 programs
• Novartis India 27 programs
• Boehringer Ingelheim 24 programs
• BRIGHT MINDS BIOSCIENCES 23 programs

1. [68Ga]Ga-PentixaFor

   CERO THERAPEUTICS HOLDINGS, INC.

   triple-negative breast cancer

   phase 1 · small molecule · active

   1 trial →

2. [68Ga]MLN6907

   Takeda

   Imaging of Solid Gastrointestinal Tumors

   phase 1 · small molecule · completed

   1 trial →

3. [^14C]-alisertib

   Takeda

   Advanced Solid Tumors

   phase 1 · small molecule · completed

   1 trial →

4. acetylsalicylic acid

   United Therapeutics Europe Ltd

   Precancerous Condition

   phase 1 · small molecule · completed

   1 trial →

5. aflibercept

   Regeneron UK Limited

   Lymphoma, Non-Hodgkin

   phase 1 · small molecule · completed

   1 trial →

6. aflibercept (AVE0005)

   Regeneron UK Limited

   Neoplasms

   phase 1 · small molecule · completed

   2 trials →

7. aflibercept (AVE0005)

   Regeneron UK Limited

   Cancer

   phase 1 · small molecule · completed

   1 trial →

8. agenT-797

   MiNK Therapeutics

   Tumor, Solid

   phase 1 · small molecule · completed

   1 trial →

9. alisertib

   Takeda

   Acinar Cell Adenocarcinoma of the Pancreas

   phase 1 · small molecule · completed

   1 trial →

10. anti-CD123 CAR-T treatment

    Nanjing Legend Biotech Co.

    Acute Leukemia

    phase 1 · small molecule · terminated

    1 trial →

11. anti-CD19 CAR-T

    The First People's Hospital of Lianyungang

    B-cell Adult Acute Lymphoblastic Leukemia

    phase 1 · mab · active

    1 trial →

12. ateganosine

    MAIA Biotechnology

    Resectable Hepatocellular Carcinoma

    phase 1 · small molecule · active

    1 trial →

13. autologous ET1402L1-CART cells

    AEON Biopharma

    Hepatocellular Carcinoma

    phase 1 · mab · terminated

    1 trial →

14. bbT369

    Regeneron UK Limited

    Diffuse Large B Cell Lymphoma (DLBCL)

    phase 1 · mab · terminated

    1 trial →

15. blinatumomab and auto-HSCT "sandwich " strategy

    The First People's Hospital of Lianyungang

    B-cell Acute Lymphoblastic Leukemia

    phase 1 · other · active

    1 trial →

16. brontictuzumab

    Mereo BioPharma Group plc

    Metastatic Colorectal Cancer

    phase 1 · small molecule · completed

    1 trial →

17. casdatifan

    Arcus Biosciences

    Clear Cell Renal Cell Carcinoma

    phase 1 · small molecule · active

    1 trial →

18. cemiplimab

    Regeneron UK Limited

    Relapsed/Refractory Aggressive B-Cell Lymphoma

    phase 1 · small molecule · active

    1 trial →

19. cisplatin oxaliplatin tegafur

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 1 · small molecule · active

    1 trial →

20. darinaparsin

    Alaunos Therapeutics

    Advanced Solid Tumors

    phase 1 · small molecule · completed

    1 trial →

21. darinaparsin

    Alaunos Therapeutics

    Lymphoma

    phase 1 · small molecule · terminated

    1 trial →

22. decitabine

    Karyopharm Therapeutics Inc

    Acute Myeloid Leukemia

    phase 1 · small molecule · completed

    1 trial →

23. dendritic cell

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Recurrent Ovarian Cancer

    phase 1 · mab · active

    1 trial →

24. engineered autologous T cells

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 1 · mab · active

    1 trial →

25. entinostat

    Syndax Pharmaceuticals

    Lung Cancer

    phase 1 · small molecule · completed

    1 trial →

26. etrumadenant

    Arcus Biosciences

    GastroEsophageal Cancer

    phase 1 · small molecule · completed

    1 trial →

27. evorpacept

    ALX ONCOLOGY HOLDINGS INC

    Acute Myeloid Leukemia

    phase 1 · small molecule · terminated

    1 trial →

28. forodesine hydrochloride

    Biocryst

    Cancer

    phase 1 · small molecule · completed

    1 trial →

29. hCD19.IL15.CAR-iNKT

    The First People's Hospital of Lianyungang

    Acute Lymphoblastic Leukemia

    phase 1 · small molecule · active

    1 trial →

30. haploid allogeneic NK cell therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Myeloid Leukemia

    phase 1 · mab · active

    1 trial →

31. human HER2-targeted CAR-M cells

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 1 · mab · active

    1 trial →

32. hypo-fractionated SRS

    United Therapeutics Europe Ltd

    Metastatic Cancer

    phase 1 · other · completed

    1 trial →

33. iC9.GD2.CAR.IL-15 T Infusion

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 1 · mab · active

    1 trial →

34. idronoxil

    KAZIA THERAPEUTICS LTD

    Unspecified Adult Solid Tumor, Protocol Specific

    phase 1 · small molecule · completed

    1 trial →

35. illuccix 68Ga-PSMA-11 Total Body PET-CT

    Telix Innovations

    Metastatic Castration-resistant Prostate Cancer

    phase 1 · small molecule · active

    1 trial →

36. imatinib mesylate

    Children's Hospital of Fudan University

    Leukemia

    phase 1 · small molecule · completed

    1 trial →

37. indibulin

    Alaunos Therapeutics

    Solid Tumors

    phase 1 · small molecule · active

    2 trials →

38. indibulin

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 · small molecule · completed

    1 trial →

39. interleukin-4 PE38KDEL cytotoxin

    NEUROCRINE BIOSCIENCES INC

    Breast Cancer

    phase 1 · mab · completed

    1 trial →

40. limonene containing massage oil

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 1 · other · completed

    1 trial →

41. liposomal cytarabine

    Pacira Ireland Limited

    Brain and Central Nervous System Tumors

    phase 1 · small molecule · active

    1 trial →

42. mitoxantrone hydrochloride

    Karyopharm Therapeutics Inc

    Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities

    phase 1 · small molecule · completed

    1 trial →

43. neratinib

    PUMA BIOTECHNOLOGY, INC.

    Tumors

    phase 1 · small molecule · completed

    1 trial →

44. nesvacumab (REGN910/ SAR307746)

    Regeneron UK Limited

    Solid Tumors

    phase 1 · small molecule · completed

    2 trials →

45. olaparib

    United Therapeutics Europe Ltd

    Advanced Cancer

    phase 1 · small molecule · completed

    1 trial →

46. ombrabulin (AVE8062)

    Sanofi Pasteur

    Neoplasms, Malignant

    phase 1 · small molecule · completed

    1 trial →

47. oncolytic virus (OVV-01) injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Neoplasms

    phase 1 · small molecule · active

    1 trial →

48. oral palifosfamide tris

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 · small molecule · on hold

    1 trial →

Frequently asked questions