Oncology · Phase I

Top sponsors

• Chinese Academy of 70 programs
• First People's Hospital 62 programs
• Takeda 49 programs
• United Therapeutics Europe 41 programs
• BEONE MEDICINES AUS 40 programs
• Regeneron UK 34 programs
• Anaxis Pharma 31 programs
• Chongqing Precision Biotech 27 programs
• Janssen-Cilag International N.V 27 programs
• Novartis India 27 programs
• Boehringer Ingelheim 24 programs
• BRIGHT MINDS BIOSCIENCES 23 programs

1. PRT2527

   Prelude Therapeutics Inc

   Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)

   phase 1 · small molecule · completed

   1 trial →

2. PRT2527

   Prelude Therapeutics Inc

   Sarcoma

   phase 1 · small molecule · completed

   1 trial →

3. PRT3645

   Prelude Therapeutics Inc

   Breast Cancer

   phase 1 · small molecule · completed

   1 trial →

4. PRT543

   Prelude Therapeutics Inc

   Relapsed/Refractory Advanced Solid Tumors

   phase 1 · small molecule · completed

   1 trial →

5. PRT7732

   Prelude Therapeutics Inc

   Advanced Solid Tumor

   phase 1 · small molecule · terminated

   1 trial →

6. PRT7732-01

   Prelude Therapeutics Inc

   esophageal, gastric, or gastroesophageal junction adenocarcinoma, esophageal, gastric, or gastroesophageal junction squamous cell carcinoma, Non-small cell lung cancer (NSCLC), Advanced or Metastatic Solid Tumors with a SMARCA4 Mutation

   phase 1 · other · active

   1 trial →

7. PRT811

   Prelude Therapeutics Inc

   Advanced Solid Tumor

   phase 1 · small molecule · completed

   1 trial →

8. PSA/IL-2/GM-CSF

   United Therapeutics Europe Ltd

   Prostate Cancer

   phase 1 · mab · active

   1 trial →

9. PTC299

   PTC THERAPEUTICS, INC.

   Metastatic Breast Cancer

   phase 1 · small molecule · completed

   1 trial →

10. PTC299

    PTC THERAPEUTICS, INC.

    Leukemia, Myeloid, Acute

    phase 1 · small molecule · terminated

    1 trial →

11. PTC299

    PTC THERAPEUTICS, INC.

    Advanced Cancer

    phase 1 · small molecule · terminated

    1 trial →

12. PTC596

    PTC THERAPEUTICS, INC.

    Cancer

    phase 1 · small molecule · completed

    1 trial →

13. PV-10 (10% rose bengal disodium)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Cancer Metastatic to the Liver

    phase 1 · small molecule · active

    1 trial →

14. PV-10 (rose bengal disodium 10%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Breast Cancer

    phase 1 · small molecule · completed

    1 trial →

15. PV-10 (rose bengal disodium, 10%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Melanoma

    phase 1 · small molecule · completed

    1 trial →

16. PVSRIPO

    United Therapeutics Europe Ltd

    Invasive Breast Cancer

    phase 1 · mab · completed

    1 trial →

17. PYX-106

    Pyxis Oncology

    Solid Tumor

    phase 1 · small molecule · active

    1 trial →

18. PYX-201

    Pyxis Oncology

    Solid Tumor

    phase 1 · small molecule · active

    1 trial →

19. Paclitaxel

    Jazz Pharmaceuticals Ireland Limited

    Ovarian Cancer

    phase 1 · small molecule · active

    1 trial →

20. Paclitaxel

    Hospital Authority, Hong Kong

    Ovarian Cancer

    phase 1 · small molecule · active

    1 trial →

21. Palazestrant

    Olema Pharmaceuticals

    Metastatic Breast Cancer

    phase 1 · small molecule · active

    1 trial →

22. Part 1 TPST-1120

    Tempest Therapeutics

    Hepatocellular Carcinoma

    phase 1 · small molecule · completed

    1 trial →

23. Part A: Dose Escalation of Cantrixil

    KAZIA THERAPEUTICS LTD

    Ovarian Neoplasms

    phase 1 · small molecule · completed

    1 trial →

24. Pazopanib

    GlaxoSmithKline

    Neoplasms, Colorectal

    phase 1 · small molecule · completed

    1 trial →

25. Pegfilgrastim

    Biotech Pharmaceutical Co.,

    Breast Cancer

    phase 1 · small molecule · completed

    1 trial →

26. Pelareorep

    ONCOLYTICS BIOTECH INC

    Breast Cancer

    phase 1 · mab · terminated

    1 trial →

27. Pembrolizumab

    United Therapeutics Europe Ltd

    Cervix Cancer

    phase 1 · other · terminated

    1 trial →

28. Pembrolizumab

    Takeda

    Carcinoma, Non-Small-Cell Lung

    phase 1 · small molecule · completed

    1 trial →

29. Pembrolizumab

    Cardiff Oncology

    Anal Cancer Stage III A

    phase 1 · small molecule · active

    1 trial →

30. Pevonedistat

    Takeda

    Acute Myelogenous Leukemia

    phase 1 · small molecule · completed

    1 trial →

31. Pevonedistat

    Takeda

    Advanced Solid Tumors, Neoplasms, Advanced Solid

    phase 1 · small molecule · completed

    1 trial →

32. Pevonedistat

    Takeda

    Refractory Acute Lymphoblastic Leukemia

    phase 1 · small molecule · completed

    1 trial →

33. Pevonedistat

    Takeda

    Advanced Solid Neoplasm

    phase 1 · small molecule · completed

    2 trials →

34. Pevonedistat 25 mg/m^2

    Takeda

    Leukemia, Myeloid, Acute

    phase 1 · small molecule · completed

    1 trial →

35. Ph 1 Study of ORIC-944 in Patients with Metastatic Prostate Cancer.

    Topiloric/Uriadec

    Prostate cancer

    phase 1 · other · active

    1 trial →

36. Phase 1 Study of IMC-P115C in Advanced PRAME Positive Cancers

    Immunocore Ireland Limited

    Advanced PRAME Positive Cancers

    phase 1 · other · active

    1 trial →

37. Phase 1 Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancer

    Janssen-Cilag International N.V.

    Metastatic colorectal cancer and Gastric cancer

    phase 1 · other · active

    1 trial →

38. Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

    Olema Pharmaceuticals

    Advanced or Metastatic Solid Tumors

    phase 1 · other · active

    1 trial →

39. Phase 1 Study of PYX-106 in Solid Tumors

    Pyxis Oncology

    Solid Tumors

    phase 1 · other · active

    1 trial →

40. Phase 1 Study of PYX-201 in Solid Tumors

    Pyxis Oncology

    Advanced solid tumors

    phase 1 · other · active

    1 trial →

41. Phase 1 trial of valemetostat and darolutamide in mCRPC

    Daiichi Sankyo

    Metastatic Castration Resistant Prostate Cancer (mCRPC)

    phase 1 · other · active

    1 trial →

42. Phase 1b Study of Tarlatamab + ZL-1310 +/- Anti-PD-L1 in Small Cell Lung Cancer

    Amgen

    Small Cell Lung Cancer

    phase 1 · other · active

    1 trial →

43. Phase I Study of PM54 Administered to Patients with Advanced Solid Tumors

    Lacuna Pharma Pty Ltd

    Selected Advanced Solid Tumors

    phase 1 · other · active

    1 trial →

44. Phase I study of 225Ac-PSMA I&T in prostate cancer

    Disc Medicine

    metastatic prostate cancer

    phase 1 · other · active

    1 trial →

45. Phase I study of MGY825 in patients with lung cancer

    Novartis Pharmaceuticals

    Advanced non-small cell lung cancer with or without NFE2L2/KEAP1/CUL3 mutations in adult patients

    phase 1 · other · active

    1 trial →

46. Pitavastatin

    United Therapeutics Europe Ltd

    Acute Myeloid Leukemia

    phase 1 · small molecule · completed

    1 trial →

47. Placebo for antibiotic

    Seres Therapeutics

    Metastatic Melanoma

    phase 1 · small molecule · completed

    1 trial →

48. Plerixafor

    United Therapeutics Europe Ltd

    Pancreatic Adenocarcinoma Metastatic

    phase 1 · small molecule · completed

    1 trial →

Frequently asked questions