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Oncology · Phase I

Oncology programs at Phase I — ClinicalTrials.gov pipeline intelligence.

Programs
1,344

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Oncology Phase I programs: NovaPharmaNews indexes 1,344 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

Top sponsors

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  1. IMP3-saRNA (YMN-136) Vaccine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-Small Cell Lung Cancer

    phase 1 mab active

    1 trial

  2. INBRX-105 - PDL1x41BB antibody

    Inhibrx Biosciences

    Metastatic Solid Tumors

    phase 1 small molecule terminated

    1 trial

  3. INBRX-109

    Inhibrx Biosciences

    Ewing Sarcoma

    phase 1 small molecule active

    1 trial

  4. INC280 single agent

    Novartis Pharmaceuticals

    Non-Small Cell Lung Cancer

    phase 1 small molecule terminated

    1 trial

  5. INCA33890

    Incyte

    Solid Tumors

    phase 1 small molecule active

    1 trial

  6. INCB099280

    Incyte

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  7. INCB099280, YERVOY 5 mg/ml concentrate for solution for infusion, YERVOY 5 mg/ml concentrate for solution for infusion

    Incyte

    Solid tumor

    phase 1 small molecule active

    1 trial

  8. INO-1400

    INOVIO PHARMACEUTICALS, INC.

    Breast Cancer

    phase 1 mab completed

    1 trial

  9. INO-3106, INO-9012

    INOVIO PHARMACEUTICALS, INC.

    Aerodigestive Precancerous Lesions and Malignancies

    phase 1 mab completed

    1 trial

  10. INTERACT stomach

    Disc Medicine

    Stomach Cancer with metastasis in the peritoneum

    phase 1 other active

    1 trial

  11. INXN-1001

    Alaunos Therapeutics

    Melanoma

    phase 1 small molecule completed

    1 trial

  12. IO-108

    BEONE MEDICINES AUS PTY LTD

    Solid Tumor, Adult

    phase 1 mab completed

    1 trial

  13. IO-108

    BEONE MEDICINES AUS PTY LTD

    Advanced Solid Tumor

    phase 1 mab completed

    1 trial

  14. IO-202

    BEONE MEDICINES AUS PTY LTD

    Solid Tumor, Adult

    phase 1 mab completed

    1 trial

  15. ION537

    IONIS PHARMACEUTICALS INC

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  16. IOV-2001

    Iovance Biotherapeutics B.V.

    Chronic Lymphocytic Leukemia

    phase 1 mab completed

    1 trial

  17. IRX4204

    IO Biotech

    Lung Cancer, Nonsmall Cell

    phase 1 small molecule terminated

    1 trial

  18. IRX5183

    IO Biotech

    Acute Myeloid Leukemia (AML)

    phase 1 small molecule terminated

    1 trial

  19. IVAC MUTANOME, RBL001/RBL002

    Atrium Therapeutics

    Melanoma

    phase 1 mab completed

    1 trial

  20. IXAZOMIB

    Takeda

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  21. Image Guided Dynamic Dosimetry

    United Therapeutics Europe Ltd

    Locally Confined Adenocarcinoma of the Prostate

    phase 1 other completed

    1 trial

  22. Imatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Solid Tumor Cancer

    phase 1 small molecule active

    1 trial

  23. Imatinib/Acetaminophen

    Novartis Pharmaceuticals

    Chronic Myeloid Leukemia (CML)

    phase 1 small molecule completed

    1 trial

  24. Improving Peptide Receptor Radionuclide Therapy with PARP inhibitors

    Disc Medicine

    locally advanced or metastatic, well-differentiated gastro-enteropancreatic neuroendocrine tumors.

    phase 1 other active

    1 trial

  25. Infigratinib

    BridgeBio Oncology Therapeutics

    Breast Cancer

    phase 1 small molecule terminated

    1 trial

  26. Infigratinib

    BridgeBio Oncology Therapeutics

    Bladder Transitional Cell Carcinoma

    phase 1 small molecule terminated

    1 trial

  27. Intralesional Cemiplimab for Adult Patients with Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

    Lacuna Pharma Pty Ltd

    Cutaneous Squamous Cell Carcinoma, Basal Cell Carcinoma

    phase 1 other active

    1 trial

  28. Intraperitoneal infusion of FAST CEA-targeted CAR-T

    Chongqing Precision Biotech Co., Ltd

    Colorectal Cancer

    phase 1 mab active

    2 trials

  29. Intravenous Artesunate

    United Therapeutics Europe Ltd

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  30. Intravenous Vitamin C

    CNS Pharmaceuticals

    Pancreatic Cancer

    phase 1 small molecule completed

    1 trial

  31. Investigator-Selected Standard PD-1/PD-L1 Inhibitor-Based Therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Solid Tumors

    phase 1 small molecule active

    1 trial

  32. Invivo CAR-T

    Chongqing Precision Biotech Co., Ltd

    B-Acute Lymphoblastic Leukemia

    phase 1 mab active

    1 trial

  33. Iopofosine I 131

    Cellectar Biosciences

    Breast Cancer

    phase 1 small molecule active

    1 trial

  34. Ipatasertib

    Hoffmann-La Roche

    Breast Cancer

    phase 1 small molecule terminated

    1 trial

  35. Ipilimumab

    VACCINEX, INC.

    Pathologic Stage IIIB Cutaneous Melanoma AJCC v8

    phase 1 mab active

    1 trial

  36. Ipilimumab

    Regeneron UK Limited

    Stage III Prostate Cancer

    phase 1 mab terminated

    1 trial

  37. Irinotecan Accord 20 mg/ml concentraat voor oplossing voor infusie

    Disc Medicine

    Gastric cancer

    phase 1 small molecule active

    1 trial

  38. Irinotecan liposome II combination therapy regimen

    Chongqing Claruvis Pharmaceutical Co.,

    Non-Muscle Invasive Bladder Urothelial Carcinoma

    phase 1 small molecule active

    1 trial

  39. Itraconazole

    United Therapeutics Europe Ltd

    Non-small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  40. Ivosidenib

    Agios Netherlands B.V.

    IDH1 Mutation Myeloid Neoplasms

    phase 1 small molecule completed

    1 trial

  41. Ixazomib

    Takeda

    Precursor Cell Lymphoblastic Leukemia-lymphoma

    phase 1 small molecule terminated

    1 trial

  42. Ixazomib

    Takeda

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  43. JANX007

    Janux Therapeutics

    Prostate Cancer

    phase 1 mab active

    1 trial

  44. JANX008

    Janux Therapeutics

    Non-Small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  45. JANX014

    Janux Therapeutics

    Prostate Cancer

    phase 1 mab active

    1 trial

  46. JNJ-56021927

    Janssen Cilag International NV

    Prostatic Neoplasms, Castration-Resistant

    phase 1 small molecule completed

    1 trial

  47. JR8603

    JiaRay Group

    Solid Tumors

    phase 1 small molecule active

    1 trial

  48. JSB462

    Novartis Pharmaceuticals

    Metastatic Prostate Cancer (mCRPC)

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many oncology Phase I programs exist?

1,344 programs match both the therapeutic area and stage filters in our published index.

Data attribution: Data sources · All pipeline programs

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