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Oncology · Phase I

Oncology programs at Phase I — ClinicalTrials.gov pipeline intelligence.

Programs
1,344

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Oncology Phase I programs: NovaPharmaNews indexes 1,344 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

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  1. entinostat

    Syndax Pharmaceuticals

    Lung Cancer

    phase 1 small molecule completed

    1 trial
  2. etrumadenant

    Arcus Biosciences

    GastroEsophageal Cancer

    phase 1 small molecule completed

    1 trial
  3. evorpacept

    ALX ONCOLOGY HOLDINGS INC

    Acute Myeloid Leukemia

    phase 1 small molecule terminated

    1 trial
  4. forodesine hydrochloride

    Biocryst

    Cancer

    phase 1 small molecule completed

    1 trial
  5. hCD19.IL15.CAR-iNKT

    The First People's Hospital of Lianyungang

    Acute Lymphoblastic Leukemia

    phase 1 small molecule active

    1 trial
  6. haploid allogeneic NK cell therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Myeloid Leukemia

    phase 1 mab active

    1 trial
  7. human HER2-targeted CAR-M cells

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 1 mab active

    1 trial
  8. hypo-fractionated SRS

    United Therapeutics Europe Ltd

    Metastatic Cancer

    phase 1 other completed

    1 trial
  9. iC9.GD2.CAR.IL-15 T Infusion

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 1 mab active

    1 trial
  10. idronoxil

    KAZIA THERAPEUTICS LTD

    Unspecified Adult Solid Tumor, Protocol Specific

    phase 1 small molecule completed

    1 trial
  11. illuccix 68Ga-PSMA-11 Total Body PET-CT

    Telix Innovations

    Metastatic Castration-resistant Prostate Cancer

    phase 1 small molecule active

    1 trial
  12. imatinib mesylate

    Children's Hospital of Fudan University

    Leukemia

    phase 1 small molecule completed

    1 trial
  13. indibulin

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule completed

    1 trial
  14. indibulin

    Alaunos Therapeutics

    Solid Tumors

    phase 1 small molecule active

    2 trials
  15. interleukin-4 PE38KDEL cytotoxin

    NEUROCRINE BIOSCIENCES INC

    Breast Cancer

    phase 1 mab completed

    1 trial
  16. limonene containing massage oil

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 1 other completed

    1 trial
  17. liposomal cytarabine

    Pacira Ireland Limited

    Brain and Central Nervous System Tumors

    phase 1 small molecule active

    1 trial
  18. mitoxantrone hydrochloride

    Karyopharm Therapeutics Inc

    Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities

    phase 1 small molecule completed

    1 trial
  19. neratinib

    PUMA BIOTECHNOLOGY, INC.

    Tumors

    phase 1 small molecule completed

    1 trial
  20. nesvacumab (REGN910/ SAR307746)

    Regeneron UK Limited

    Solid Tumors

    phase 1 small molecule completed

    2 trials
  21. olaparib

    United Therapeutics Europe Ltd

    Advanced Cancer

    phase 1 small molecule completed

    1 trial
  22. ombrabulin (AVE8062)

    Sanofi Pasteur

    Neoplasms, Malignant

    phase 1 small molecule completed

    1 trial
  23. oncolytic virus (OVV-01) injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Neoplasms

    phase 1 small molecule active

    1 trial
  24. oral palifosfamide tris

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule on hold

    1 trial
  25. pCAR-19B cells

    Chongqing Precision Biotech Co., Ltd

    Acute Lymphoblastic Leukemia, in Relapse

    phase 1 mab active

    1 trial
  26. pTVG-HP with rhGM-CSF

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 1 mab completed

    1 trial
  27. palifosfamide-tris

    Alaunos Therapeutics

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial
  28. pd-1 and DC-NK cells

    The First People's Hospital of Lianyungang

    Solid Tumor

    phase 1 small molecule active

    1 trial
  29. pd-1 and dc-cik cells

    The First People's Hospital of Lianyungang

    Solid Tumor

    phase 1 small molecule active

    1 trial
  30. prophylactic 4SCAR19 cells

    The First People's Hospital of Lianyungang

    B Acute Lymphoblastic Leukemia

    phase 1 gene therapy active

    1 trial
  31. rSIFN-co

    Sichuan Provincial People's Hospital

    Carcinoma, Non-Small-Cell Lung

    phase 1 small molecule completed

    1 trial
  32. selinexor

    Karyopharm Therapeutics Inc

    B-cell Lymphoma

    phase 1 small molecule completed

    1 trial
  33. selinexor

    Karyopharm Therapeutics Inc

    Recurrent Melanoma

    phase 1 small molecule completed

    1 trial
  34. sphingosine kinase-2 inhibitor ABC294640

    Apogee Therapeutics

    Pancreatic Cancer

    phase 1 small molecule completed

    1 trial
  35. standard chemotherapy medicine combined with Chinese herbs

    The First People's Hospital of Lianyungang

    Carcinoma, Non-Small-Cell Lung

    phase 1 small molecule active

    1 trial
  36. standard dose capecitabine

    Karyopharm Therapeutics Inc

    Rectal Neoplasms

    phase 1 small molecule active

    1 trial
  37. uCD7 CART

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Myeloid Leukemia (AML)

    phase 1 mab active

    1 trial
  38. universal CLL1 CAR-T cells

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 1 mab active

    1 trial
  39. veliparib

    BRIGHT MINDS BIOSCIENCES INC.

    Small Cell Lung Cancer SCLC

    phase 1 small molecule active

    1 trial
  40. zanzalintinib

    Arcus Biosciences

    Advanced Clear Cell Renal Cell Carcinoma or Other Advanced Solid Tumors

    phase 1 small molecule terminated

    1 trial
  41. ziftomenib

    Kura Oncology

    Gastrointestinal Stromal Tumor (GIST)

    phase 1 small molecule active

    1 trial
  42. zimberelimab

    Arcus Biosciences

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial
  43. ziv-aflibercept

    Regeneron UK Limited

    Cancer

    phase 1 mab completed

    2 trials
  44. ziv-aflibercept

    Regeneron UK Limited

    Lymphoma

    phase 1 mab completed

    2 trials
  45. α-lactalbumin vaccine

    Anixa Biosciences Inc

    Pathologic Stage IIA-IIIC Triple-Negative Breast Cancer

    phase 1 mab active

    1 trial
  46. γδT Cell infusion agent

    The First People's Hospital of Lianyungang

    Leukemia, B-cell

    phase 1 small molecule active

    1 trial
  47. ​​AMG 436 as monotherapy and combination therapy in participants with Microsatellite Instability-High/Mismatch Repair Deficient Solid Tumors ​

    Amgen

    microsatellite instability high/mismatch repair deficient (MSI-H/dMMR) solid tumors

    phase 1 other active

    1 trial
  48. „INSIGHT“ An explorative, open-labeled, phase I trial to evaluate feasibility and safety of eftilagimod alpha (IMP321, a LAG-3Ig fusion protein acting as LAG-3 agonist) in combination with immunotherapeutic, targeted or chemotherapeutic agents or when administered via new routes of application in advanced stage solid tumors

    The George Institute

    Histologically confirmed locally advanced or metastatic solid tumor (Strata A, B, D): Specification for Stratum C: Only patients with NSCLC adenocarcinomas, (squamous or adenosquamous not permitted) who are scheduled to receive platin + pembrolizumab + pemetrexed standard treatment (only for Stratum C) Specification for Stratum E: Including only metastatic or irresectable locally advanced urothelial carcinomas (only for Stratum E)

    phase 1 other active

    1 trial

Frequently asked questions

How many oncology Phase I programs exist?

1,344 programs match both the therapeutic area and stage filters in our published index.

Data attribution: Data sources · All pipeline programs