Oncology · Phase I Pipeline

Quick answer

Oncology Phase I programs: NovaPharmaNews indexes 1,319 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

Top sponsors

Pipeline programs

Page 13 of 28

Ex-vivo expanded allogeneic γδT cells

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Non-Hodgkin's Lymphoma (NHL)

phase 1 mab active

1 trial
FATE-NK100

Zafatek

HER2 Positive Gastric Cancer

phase 1 small molecule completed

1 trial
FHD-286

Foghorn Therapeutics

Metastatic Uveal Melanoma

phase 1 small molecule terminated

1 trial
FHD-609

Foghorn Therapeutics

Advanced Synovial Sarcoma

phase 1 small molecule terminated

1 trial
FP-1039

Prime Medicine

Advanced Cancer

phase 1 small molecule completed

1 trial
FPA144

Prime Medicine

Advanced Solid Tumors

phase 1 small molecule completed

1 trial
FPA150

Prime Medicine

Breast Cancer

phase 1 mab terminated

1 trial
FPI-2505-001

Lacuna Pharma Pty Ltd

small cell lung cancer, non-smallcell lung cancer, colorectal cancer, breast cancer, Pancreatic cancer and gastric cancer

phase 1 other active

1 trial
FPT155

Prime Medicine

Advanced Solid Tumors

phase 1 mab terminated

1 trial
FT500

Zafatek

Advanced Solid Tumors

phase 1 small molecule completed

1 trial
FT516

Zafatek

Solid Tumor, Adult

phase 1 small molecule terminated

1 trial
FT516

Zafatek

Acute Myelogenous Leukemia

phase 1 small molecule terminated

1 trial
FT522

Zafatek

Relapsed/Refractory B-Cell Lymphoma

phase 1 small molecule completed

1 trial
FT536

Zafatek

Non Small Cell Lung Cancer

phase 1 small molecule terminated

1 trial
FT538

Zafatek

Acute Myeloid Leukemia

phase 1 small molecule terminated

1 trial
FT538

Zafatek

Solid Tumor, Adult

phase 1 small molecule terminated

1 trial
FT596

Zafatek

Lymphoma, B-Cell

phase 1 small molecule terminated

1 trial
FT596

Zafatek

Diffuse Large B Cell Lymphoma

phase 1 small molecule terminated

1 trial
FT819

Zafatek

Lymphoma, B-Cell

phase 1 small molecule active

1 trial
FT825

Zafatek

Advanced Solid Tumor

phase 1 small molecule active

1 trial
FT836

Zafatek

Non-Small Cell Lung Cancer

phase 1 small molecule active

1 trial
FURMO-002

ArriVent BioPharma

Non-Small Cell Lung Cancer (NSCLC) harboring activating EGFR or HER2 kinase domain mutations

phase 1 other active

1 trial
FYB206-C1-01

Formycon AG

Melanoma: Adjuvant treatment of patients with Stage IIB, IIC, or III melanoma following complete resection

phase 1 other active

1 trial
Fast Dual CAR-T Injection

Xiyuan Hospital of China Academy of Chinese Medical Sciences

B-cell Lymphoma

phase 1 mab terminated

1 trial
First in human study of the infusion of ARI00...

The George Institute

Relapsed/refractory B-cell aggressive lymphoma

phase 1 other active

1 trial
First-in-Human Trial of DS3610a in Participants with Advanced Solid Tumors

Daiichi Sankyo

Advanced Solid Tumors

phase 1 other active

1 trial
First-in-Human trial of DS9051b in participants with advanced solid tumors

Daiichi Sankyo

Advanced or Metastatic Adrenocortical Carcinoma (ACC), Metastatic Castration-resistant Prostate Cancer (CRPC)

phase 1 other active

1 trial
First-in-human (FIH) Study of DS-1471a in Subjects with Advanced Solid Tumors

Daiichi Sankyo

Advanced Solid Tumors

phase 1 other active

1 trial
First-in-human Trial of DS-2243a in Participants with Advanced Solid Tumors

Daiichi Sankyo

Advanced Solid Tumor

phase 1 other active

1 trial
Follicle Stimulating Hormone Receptor T Cells

Anixa Biosciences Inc

Ovarian Cancer

phase 1 small molecule active

1 trial
Fostamatinib 100 mg bid and Paclitaxel

RIGEL PHARMACEUTICALS INC

Ovarian Cancer

phase 1 small molecule completed

1 trial
Fostamatinib in combination with chemotherapy (gemcitabine and nab-paclitaxel)

RIGEL PHARMACEUTICALS INC

Pancreatic Ductal Adenocarcinoma (PDAC)

phase 1 other active

1 trial
Furmonertinib

ArriVent BioPharma

Non-Small Cell Lung Cancer (NSCLC)

phase 1 small molecule active

1 trial
G207

BRIGHT MINDS BIOSCIENCES INC.

Supratentorial Neoplasms, Malignant

phase 1 mab completed

1 trial
GB-4362

Generate Biomedicines

Advanced Urothelial Cancer

phase 1 small molecule active

1 trial
GB-5267 - IV only

Generate Biomedicines

Platinum-resistant Ovarian Cancer

phase 1 mab active

1 trial
GC4419

Galera Therapeutics

Squamous Cell Carcinoma of the Oral Cavity

phase 1 small molecule completed

1 trial
GCAR1

Chongqing Precision Biotech Co., Ltd

Sarcoma

phase 1 mab active

1 trial
GCC2005

Artiva Biotherapeutics

Lymphoma, T-Cell

phase 1 small molecule active

1 trial
GCT1056-01

Genmab A/S

Advanced solid tumors

phase 1 other active

1 trial
GCT1057-01

Genmab A/S

Metastatic or advanced malignant solid tumors

phase 1 other active

1 trial
GCT1079-01

Genmab A/S

Advanced Malignant Solid Tumors

phase 1 other active

1 trial
GCT3018-01

Genmab A/S

Relapsed or Refractory Acute Myeloid Leukemia or Higher-Risk Myelodysplastic Syndrome

phase 1 other active

1 trial
GDC-0084

KAZIA THERAPEUTICS LTD

Brain and Central Nervous System Tumors

phase 1 small molecule completed

1 trial
GEN1042

Genmab A/S

Malignant Solid Tumor

phase 1 mab active

1 trial
GK01 Injection

The First People's Hospital of Lianyungang

Advanced Solid Tumors

phase 1 small molecule active

1 trial
GLA-SE

Lxo Ireland Designated Activity Company

Merkel Cell Carcinoma

phase 1 mab completed

1 trial
GLPG0187

Lakefront Biotherapeutics NV

Solid Tumors

phase 1 small molecule completed

1 trial

Frequently asked questions

How many oncology Phase I programs exist?

1,319 programs match both the therapeutic area and stage filters in our published index.

Quick answer

Top sponsors

Pipeline programs

Ex-vivo expanded allogeneic γδT cells

FATE-NK100

FHD-286

FHD-609

FP-1039

FPA144

FPA150

FPI-2505-001

FPT155

FT500

FT516

FT516

FT522

FT536

FT538

FT538

FT596

FT596

FT819

FT825

FT836

FURMO-002

FYB206-C1-01

Fast Dual CAR-T Injection

First in human study of the infusion of ARI00...

First-in-Human Trial of DS3610a in Participants with Advanced Solid Tumors

First-in-Human trial of DS9051b in participants with advanced solid tumors

First-in-human (FIH) Study of DS-1471a in Subjects with Advanced Solid Tumors

First-in-human Trial of DS-2243a in Participants with Advanced Solid Tumors

Follicle Stimulating Hormone Receptor T Cells

Fostamatinib 100 mg bid and Paclitaxel

Fostamatinib in combination with chemotherapy (gemcitabine and nab-paclitaxel)

Furmonertinib

G207

GB-4362

GB-5267 - IV only

GC4419

GCAR1

GCC2005

GCT1056-01

GCT1057-01

GCT1079-01

GCT3018-01

GDC-0084

GEN1042

GK01 Injection

GLA-SE

GLPG0187

Frequently asked questions

Stay Ahead in Pharma