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Intelligence · Clinical pipeline

Metabolic & obesity R&D Pipeline

GLP-1, metabolic disease, obesity, and diabetes pipeline programs with sponsor and trial ID cross-links.

Programs 744

Quick answer

Metabolic & obesity: NovaPharmaNews indexes 744 metabolic & obesity clinical pipeline programs from ClinicalTrials.gov with phase, modality, NCT identifiers, and sponsor company links. GLP-1, metabolic disease, obesity, and diabetes pipeline programs with sponsor and trial ID cross-links.

Top sponsors

Pipeline programs

Page 5 of 16

  1. Tradipitant

    Lacuna Pharma Pty Ltd

    Idiopathic or diabetic gastroparesis with moderate to severe nausea.

    phase 3 small molecule active

    1 trial

  2. Trelagliptin 25 mg

    Takeda

    Type 2 Diabetes Mellitus

    phase 3 small molecule completed

    1 trial

  3. Trichosanthes root

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Diabetes Mellitus

    phase 3 small molecule active

    1 trial

  4. Trulicity 0.75 mg solution for injection in pre-filled pen

    The George Institute

    Preventive treatment of post-kidney transplant diabetes

    phase 3 small molecule active

    1 trial

  5. Trulicity 0.75 mg solution for injection in pre-filled pen

    The George Institute

    Metabolic syndrome in patients on the waiting list for kidney transplantation, Metabolic syndrome in patients on the waiting list for kidney transplantation

    phase 3 small molecule active

    1 trial

  6. UDCA

    The First People's Hospital of Lianyungang

    Diabetes Mellitus

    phase 3 small molecule active

    1 trial

  7. VEGF Trap-Eye (BAY86-5321)

    Regeneron UK Limited

    Diabetes Mellitus

    phase 3 mab completed

    1 trial

  8. VX-880

    Vertex Pharmaceuticals (Australia) Pty.

    Diabetes Mellitus, Type 1

    phase 3 mab active

    1 trial

  9. VX-880 solution for infusion

    Vertex Pharmaceuticals (Australia) Pty.

    Type 1 Diabetes Mellitus with Impaired Hypoglycemic Awareness and Severe Hypoglycemia

    phase 3 small molecule active

    1 trial

  10. Vildagliptin

    Novartis Pharmaceuticals

    Diabetes Mellitus, Type 2

    phase 3 small molecule completed

    1 trial

  11. Vildagliptin

    Novartis Pharmaceuticals

    Type 2 Diabetes Mellitus

    phase 3 small molecule completed

    1 trial

  12. WC45725

    Hoffmann-La Roche

    Obesity or Overweight Without Type 2 Diabetes

    phase 3 small molecule active

    1 trial

  13. WC45726

    Hoffmann-La Roche

    Obesity or Overweight and Type 2 Diabetes

    phase 3 small molecule active

    1 trial

  14. Wegovy solution for Diabetes Mellitus, Cardiovascul…

    Istituto Gentili S.r.l.

    Diabetes Mellitus, Cardiovascular disease, Overweight (BMI ≥27 kg/m²), Obesity (BMI≥30kg/m2)

    phase 3 small molecule active

    1 trial

  15. aflibercept 8 mg PFS

    Regeneron UK Limited

    Diabetic Macular Edema (DME)

    phase 3 small molecule completed

    1 trial

  16. albiglutide + insulin glargine

    GlaxoSmithKline

    Diabetes Mellitus, Type 2

    phase 3 mab completed

    1 trial

  17. biphasic insulin aspart

    Novo Nordisk A/S

    Diabetes

    phase 3 small molecule completed

    1 trial

  18. candesartan

    Takeda

    Type 1 Diabetes

    phase 3 small molecule completed

    1 trial

  19. candesartan

    Takeda

    Type 2 Diabetes

    phase 3 small molecule completed

    1 trial

  20. candesartan cilexetil

    Takeda

    Type 1 Diabetes

    phase 3 small molecule completed

    1 trial

  21. evogliptin

    Dong Wang

    Type 2 Diabetes Mellitus

    phase 3 small molecule completed

    1 trial

  22. exenatide once weekly

    AstraZeneca

    Type 2 Diabetes Mellitus

    phase 3 small molecule completed

    2 trials

  23. fluocinolone acetonide

    ANI PHARMACEUTICALS INC

    Diabetic Macular Edema

    phase 3 small molecule completed

    3 trials

  24. insulin degludec

    Novo Nordisk A/S

    Diabetes

    phase 3 small molecule completed

    2 trials

  25. linagliptine 5 mg

    Boehringer Ingelheim

    Diabetes Mellitus, Type 2

    phase 3 small molecule completed

    1 trial

  26. liraglutide

    Novo Nordisk A/S

    Diabetes

    phase 3 small molecule completed

    2 trials

  27. lixisenatide AVE0010

    Sanofi Pasteur

    Type 2 Diabetes Mellitus

    phase 3 small molecule completed

    1 trial

  28. lorcaserin

    BRIGHT MINDS BIOSCIENCES INC.

    Obesity

    phase 3 small molecule terminated

    1 trial

  29. muraglitazar

    Bristol-Myers Squibb

    Diabetes Mellitus, Type 2

    phase 3 small molecule completed

    1 trial

  30. ofloxacin

    ABEONA THERAPEUTICS INC.

    Diabetic Foot Ulcers

    phase 3 small molecule completed

    2 trials

  31. pioglitazone

    Hoffmann-La Roche

    Diabetes Mellitus Type 2

    phase 3 small molecule completed

    1 trial

  32. placebo to match albiglutide

    GlaxoSmithKline

    Diabetes Mellitus, Type 2

    phase 3 small molecule completed

    1 trial

  33. rosiglitazone

    Novo Nordisk A/S

    Diabetes

    phase 3 small molecule terminated

    1 trial

  34. semaglutide

    Novo Nordisk A/S

    Diabetes

    phase 3 small molecule completed

    4 trials

  35. survodutide

    Boehringer Ingelheim

    Obesity

    phase 3 other active

    1 trial

  36. 0.59 mg fluocinolone acetonide intravitreal implant

    Bausch & Lomb Incorporated

    Diabetic Macular Edema

    phase 2 small molecule completed

    1 trial

  37. 10mg DS-8500a tablet

    Daiichi Sankyo

    Type 2 Diabetes Mellitus

    phase 2 small molecule completed

    1 trial

  38. 1485-0018

    Boehringer Ingelheim

    Centre-involved diabetic macular edema

    phase 2 small molecule active

    1 trial

  39. 21839

    Bayer AG

    Chronic kidney disease in type 2 diabetes mellitus

    phase 2 small molecule active

    1 trial

  40. 2HPβCD

    ZyVersa Therapeutics

    Diabetic Kidney Disease

    phase 2 small molecule terminated

    1 trial

  41. 3-V Bioscience-2640

    Sagimet Biosciences

    Metabolic Syndrome

    phase 2 small molecule completed

    1 trial

  42. 3133004

    Orion Laboratories Pty.

    CHRONIC PAIN DUE TO DIABETIC PERIPHERAL NEUROPATHY

    phase 2 small molecule active

    1 trial

  43. 4D-150 IVT

    4D Molecular Therapeutics

    Diabetic Macular Edema

    phase 2 mab active

    1 trial

  44. 5% Bisphosphocin Topical Gel

    Lakewood-Amedex Biotherapeutics

    Chronic Diabetic Foot Ulcers

    phase 2 small molecule terminated

    1 trial

  45. 5% Nu-3 gel

    Lakewood-Amedex Biotherapeutics

    Diabetic Foot Infection

    phase 2 small molecule active

    1 trial

  46. 75 mg LX4211

    LEXICON PHARMACEUTICALS, INC.

    Type 2 Diabetes Mellitus

    phase 2 small molecule completed

    1 trial

  47. ALG-055009

    Aligos Therapeutics

    NASH

    phase 2 small molecule completed

    1 trial

  48. ALN-2232

    Alnylam Netherlands B.V.

    Obesity

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many metabolic & obesity pipeline programs are tracked?

744 programs match this therapeutic area based on indication text, program name, and registry metadata.

Where does pipeline data come from?

ClinicalTrials.gov records linked to NovaPharmaNews company profiles. Verify on ClinicalTrials.gov before investment decisions.

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