Friday, July 10, 2026

Intelligence · Clinical pipeline

Metabolic & obesity R&D Pipeline

GLP-1, metabolic disease, obesity, and diabetes pipeline programs with sponsor and trial ID cross-links.

Programs 744

Quick answer

Metabolic & obesity: NovaPharmaNews indexes 744 metabolic & obesity clinical pipeline programs from ClinicalTrials.gov with phase, modality, NCT identifiers, and sponsor company links. GLP-1, metabolic disease, obesity, and diabetes pipeline programs with sponsor and trial ID cross-links.

Top sponsors

Pipeline programs

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  1. [14C]HSK7653

    The First People's Hospital of Lianyungang

    Type II Diabetes

    phase 1 small molecule completed

    1 trial
  2. administration of UI068

    United Therapeutics Europe Ltd

    Diabetes Mellitus, Type 2

    phase 1 small molecule completed

    1 trial
  3. avoralstat

    Biocryst

    Diabetic Macular Edema (DME)

    phase 1 small molecule terminated

    1 trial
  4. hVEGF-A

    SANGAMO THERAPEUTICS, INC

    Diabetic Neuropathy

    phase 1 gene therapy completed

    1 trial
  5. intraconazole

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis

    phase 1 small molecule completed

    1 trial
  6. pyroglutamate rongliflozin capsules

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Type 2 Diabetes

    phase 1 small molecule completed

    1 trial
  7. pyroglutamate rongliflozin capsules

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Diabetes Mellitus, Type 2

    phase 1 small molecule completed

    1 trial
  8. removal of omentum

    United Therapeutics Europe Ltd

    Diabetes Mellitus Type 2

    phase 1 other completed

    1 trial
  9. salvianolic acid A

    The First People's Hospital of Lianyungang

    Diabetes

    phase 1 small molecule active

    1 trial
  10. 116795

    Disc Medicine

    Type 1 Diabetes

    approved small molecule active

    1 trial
  11. 18253

    Disc Medicine

    Albuminuria, Type 2 diabetes

    approved small molecule active

    1 trial
  12. AD-4833 15 mg

    Takeda

    Diabetes Mellitus

    approved small molecule completed

    1 trial
  13. ANGELO

    The George Institute

    Obesity

    approved small molecule active

    1 trial
  14. Aflibercept

    Regeneron UK Limited

    Diabetic Macular Edema

    approved small molecule completed

    2 trials
  15. Aflibercept

    Regeneron UK Limited

    Diabetic Retinopathy

    approved small molecule completed

    2 trials
  16. Aflibercept (BAY86-5321, Eylea)

    Regeneron UK Limited

    Diabetic Macular Edema

    approved small molecule completed

    1 trial
  17. Aflibercept 8 mg (VEGF Trap-Eye, BAY86-5321)

    Regeneron UK Limited

    Diabetic Macular Edema (DME)

    approved small molecule active

    1 trial
  18. Aflibercept Injection

    Regeneron UK Limited

    Diabetic Retinopathy

    approved small molecule completed

    2 trials
  19. Alogliptin

    Takeda

    Diabetes Mellitus, Type 2

    approved small molecule completed

    6 trials
  20. Azilsartan

    Takeda

    Essential Hypertension Complicated by Type 2 Diabetes Mellitus

    approved small molecule completed

    1 trial
  21. Berberine

    The First People's Hospital of Lianyungang

    Diabetes Mellitus

    approved small molecule completed

    1 trial
  22. Berberine plus lifestyle intervention

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Obesity

    approved small molecule completed

    1 trial
  23. BioPhenoT2D

    Fondazione Telethon ETS

    type 2 diabetes

    approved small molecule active

    1 trial
  24. Blood Glucose Meter Systems

    Universal Integrated

    Diabetes

    approved other completed

    1 trial
  25. Breeze2 glucometer

    Hospital Authority, Hong Kong

    Diabetes

    approved other active

    1 trial
  26. CSII

    The First People's Hospital of Lianyungang

    Diabetes Mellitus, Type 2

    approved small molecule completed

    1 trial
  27. Candesartan and Hydrochlorothiazide

    Takeda

    Obesity

    approved small molecule completed

    1 trial
  28. Commercial Hylenex® recombinant (hyaluronidase human injection)

    HALOZYME THERAPEUTICS, INC.

    Type 1 Diabetes Mellitus

    approved small molecule completed

    1 trial
  29. DON3

    Fondazione Telethon ETS

    obese elderly people with vitamin D deficiency

    approved small molecule active

    1 trial
  30. Dapagliflozin

    AstraZeneca

    Diabetes Mellitus, Type 2

    approved small molecule completed

    1 trial
  31. Dapagliflozin 10 MG

    The First People's Hospital of Lianyungang

    Type 2 Diabetes Mellitus

    approved small molecule active

    1 trial
  32. EPHIC-DIA2

    The George Institute

    Type 2 Diabetes Mellitus

    approved small molecule active

    1 trial
  33. ESOMEPRAZOLE, ESOMEPRAZOLE

    Fondazione Telethon ETS

    obesity

    approved small molecule active

    1 trial
  34. EXPAREL

    Pacira Ireland Limited

    Obesity

    approved small molecule completed

    1 trial
  35. Exenatide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Type 2 Diabetes Mellitus

    approved small molecule completed

    1 trial
  36. Exenatide

    The First People's Hospital of Lianyungang

    Type 2 Diabetes

    approved small molecule active

    1 trial
  37. Eylea 114.3 mg/ml solution for injection

    Bayer AG

    Neovascular age-related macular degeneration (nAMD), Diabetic macular edema (DME)

    approved small molecule active

    1 trial
  38. Fenofibrate 145 mg

    United Therapeutics Europe Ltd

    Diabetic Retinopathy

    approved small molecule completed

    1 trial
  39. Fespixon Cream

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Diabetic Foot Ulcer (DFU)

    approved small molecule terminated

    1 trial
  40. Finerenone

    Chinese University of Hong Kong

    Patients With Type 2 Diabetes

    approved small molecule active

    1 trial
  41. Glucagon-like peptide-1 receptor agonist:Semaglutide

    The First People's Hospital of Lianyungang

    Type 2 Diabetes

    approved small molecule active

    1 trial
  42. Henagliflozin Proline Tablets treatment

    The First People's Hospital of Lianyungang

    Diabetes Type 2

    approved small molecule active

    1 trial
  43. ILUVIEN

    ANI PHARMACEUTICALS INC

    Chronic Diabetic Macular Edema

    approved small molecule completed

    1 trial
  44. ILUVIEN 0.19 MG

    ANI PHARMACEUTICALS INC

    Diabetic Macular Edema (DME)

    approved small molecule completed

    1 trial
  45. INSULIN GLARGINE

    Sanofi-aventis Healthcare Pty Ltd

    Diabetes mellitus II

    approved small molecule active

    1 trial
  46. INSULIN GLARGINE (HOE901)

    Sanofi Pasteur

    Diabetes Mellitus, Type 2

    approved small molecule terminated

    1 trial
  47. IVC

    The First People's Hospital of Lianyungang

    Proliferative Diabetic Retinopathy

    approved small molecule active

    1 trial
  48. Iluvien 0.19 MG Drug Implant

    ANI PHARMACEUTICALS INC

    Diabetic Macular Edema

    approved small molecule active

    1 trial

Frequently asked questions

How many metabolic & obesity pipeline programs are tracked?

744 programs match this therapeutic area based on indication text, program name, and registry metadata.

Where does pipeline data come from?

ClinicalTrials.gov records linked to NovaPharmaNews company profiles. Verify on ClinicalTrials.gov before investment decisions.