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Intelligence · Clinical pipeline

Metabolic & obesity · Phase I

Metabolic & obesity programs at Phase I — ClinicalTrials.gov pipeline intelligence.

Programs 148

Quick answer

Metabolic & obesity Phase I programs: NovaPharmaNews indexes 148 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

Top sponsors

Pipeline programs

Page 3 of 4

  1. NN1679-8505

    NovoThirteen

    Healthy participants and participants with type 2 diabetes

    phase 1 other active

    1 trial

  2. NN6022-7683

    NovoThirteen

    Cardiometabolic diseases

    phase 1 other active

    1 trial

  3. NN6497-8309

    NovoThirteen

    Type I diabetes

    phase 1 other active

    1 trial

  4. NN6497-8316

    NovoThirteen

    Diabetes mellitus type 1

    phase 1 other active

    1 trial

  5. NN6705-8141

    NovoThirteen

    Cardiometabolic diseases with an inflammatory component

    phase 1 other active

    1 trial

  6. NN9388-7782

    NovoThirteen

    Type 2 diabetes

    phase 1 other active

    1 trial

  7. NN9490-7611

    NovoThirteen

    Obesity and Diabetes mellitus Typ 2

    phase 1 other active

    1 trial

  8. NN9490-8151

    NovoThirteen

    Participants with obesity, but otherwise healthy

    phase 1 other active

    1 trial

  9. NN9490-8152

    NovoThirteen

    Obesity

    phase 1 other active

    1 trial

  10. NN9541-4922

    NovoThirteen

    Healthy postmenopausal females (Type 2 Diabetes)

    phase 1 other active

    1 trial

  11. NN9541-4923

    NovoThirteen

    Type 2 Diabetes Mellitus

    phase 1 other active

    1 trial

  12. NN9541-7760

    NovoThirteen

    Type 2 diabetes mellitus

    phase 1 other active

    1 trial

  13. NN9541-8116

    NovoThirteen

    Obesity, Type 2 Diabetes with either overweight or obesity

    phase 1 other active

    1 trial

  14. NN9733-8133

    NovoThirteen

    Healthy Participants and Participants with type 2 diabetes

    phase 1 other active

    1 trial

  15. NN9833-8285

    NovoThirteen

    obesity

    phase 1 other active

    1 trial

  16. NN9833-8421

    NovoThirteen

    Obesity

    phase 1 other active

    1 trial

  17. NN9838-4695

    NovoThirteen

    Obesity

    phase 1 other active

    1 trial

  18. NN9838-8411

    NovoThirteen

    Obesity, CCI, CCI

    phase 1 other active

    1 trial

  19. NNC0480-0389

    Novo Nordisk A/S

    Healthy Volunteers Type 2 Diabetes

    phase 1 small molecule completed

    1 trial

  20. Omega-3 fatty acids

    NORTHWEST BIOTHERAPEUTICS INC

    Metabolic Syndrome X

    phase 1 other active

    1 trial

  21. Oshadi Oral Insulin

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetes

    phase 1 small molecule completed

    1 trial

  22. PF-05190457

    Pfizer

    Diabetes Mellitus, Type 2

    phase 1 small molecule completed

    1 trial

  23. Placebo

    Rhythm Pharmaceuticals Netherlands B.V.

    Obesity

    phase 1 small molecule completed

    1 trial

  24. ProHema-CB Transplant

    Zafatek

    Metabolic Disorders

    phase 1 mab terminated

    1 trial

  25. REGN1193

    Regeneron UK Limited

    Diabetes Mellitus, Type 2

    phase 1 small molecule terminated

    1 trial

  26. REGN1500

    Regeneron UK Limited

    Metabolic Disorders

    phase 1 small molecule completed

    1 trial

  27. REGN20934

    Regeneron UK Limited

    Overweight or Obesity

    phase 1 small molecule active

    1 trial

  28. RP-L301-0119

    Lacuna Pharma Pty Ltd

    Inherited metabolic disorder of the enzyme pyruvate kinase which affects the survival of red blood cells, Pyruvate Kinase Deficiency

    phase 1 small molecule active

    1 trial

  29. RT-114 is the RaniPill capsule with PG-102 for the treatment of obesity

    Rani Therapeutics Holdings

    Obesity

    phase 1 other active

    1 trial

  30. Rongliflozin

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  31. Salvianolic Acid A

    The First People's Hospital of Lianyungang

    Neuropathy of Diabetes

    phase 1 small molecule active

    1 trial

  32. TAK-329

    Takeda

    Type 1 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  33. TAK-648

    Takeda

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  34. Tebipenem Pivoxil Hydrobromide

    Spero Therapeutics

    Diabetes

    phase 1 small molecule completed

    1 trial

  35. The Role of the Amylin Analogue Cagrilintide in Bone Metabolism

    NovoThirteen

    Female (aged between 50-70 years (both included)) with obesity (BMI ≥ 30.0 kg/m2) of post-menopausal state at screening (defined as minimum 12 months of amenorrhea and high levels of follicular stimulating hormone (FSH) ≥16 UI/L. In cases of uncertainty, confirmation of postmenopausal status requires low levels of anti-Müllerian hormone (AMH) and inhibin B).

    phase 1 other active

    1 trial

  36. UECHUP-DAP/24-4

    Laboratorios Tillomed Spain S.L.U

    Diabetes

    phase 1 other active

    1 trial

  37. UECHUP-LIN-MET/24-1

    Laboratorios Tillomed Spain S.L.U

    diabetes

    phase 1 other active

    1 trial

  38. UP421

    Sana Biotechnology

    Type1diabetes

    phase 1 mab active

    1 trial

  39. VCTX210A unit

    S.A.

    Diabetes Mellitus

    phase 1 other completed

    1 trial

  40. VCTX211

    S.A.

    Diabetes Mellitus

    phase 1 other terminated

    1 trial

  41. VEGF Trap-Eye

    Regeneron UK Limited

    Diabetic Macular Edema

    phase 1 small molecule completed

    1 trial

  42. XeriSol glucagon

    Xeris Biopharma Holdings

    Type1diabetes

    phase 1 small molecule completed

    1 trial

  43. [14C]-rencofilstat 225mg

    Hepion Pharmaceuticals

    NASH With Fibrosis

    phase 1 small molecule completed

    1 trial

  44. [14C]HSK7653

    The First People's Hospital of Lianyungang

    Type II Diabetes

    phase 1 small molecule completed

    1 trial

  45. administration of UI068

    United Therapeutics Europe Ltd

    Diabetes Mellitus, Type 2

    phase 1 small molecule completed

    1 trial

  46. avoralstat

    Biocryst

    Diabetic Macular Edema (DME)

    phase 1 small molecule terminated

    1 trial

  47. hVEGF-A

    SANGAMO THERAPEUTICS, INC

    Diabetic Neuropathy

    phase 1 gene therapy completed

    1 trial

  48. intraconazole

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many metabolic & obesity Phase I programs exist?

148 programs match both the therapeutic area and stage filters in our published index.

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