Infectious disease · Phase I

Top sponsors

• United Therapeutics Europe 23 programs
• ENANTA PHARMACEUTICALS 14 programs
• Vertex Pharmaceuticals (Australia) 11 programs
• BRIGHT MINDS BIOSCIENCES 10 programs
• Chinese Academy of 10 programs
• ASSEMBLY BIOSCIENCES 9 programs
• Aligos Therapeutics 8 programs
• Anaxis Pharma 8 programs
• Sunshine Guojian Pharmaceutical 8 programs
• INOVIO Pharmaceuticals 7 programs
• MSD Merck Sharp 6 programs
• Sinovac Research and 6 programs

1. SB-728-T

   SANGAMO THERAPEUTICS, INC

   HIV Infection

   phase 1 · gene therapy · completed

   1 trial →

2. SB-728mR-HSPC Infusion 3 days following busulfan conditioning

   SANGAMO THERAPEUTICS, INC

   HIV

   phase 1 · gene therapy · active

   1 trial →

3. SER-262

   Seres Therapeutics

   Clostridium Difficile Infection

   phase 1 · small molecule · completed

   1 trial →

4. SOF/VEL/VOX

   Gilead Sciences Ireland UC

   HCV Infection

   phase 1 · small molecule · completed

   1 trial →

5. Sinovac PCV24 formulation 1

   Sinovac Research and Development Co.,

   Pneumococcal Infectious Disease

   phase 1 · mab · completed

   2 trials →

6. Sotrovimab

   Vir Biotechnology

   COVID-19 Infection

   phase 1 · mab · terminated

   1 trial →

7. Sporozoite Challenge Model for Plasmodium vivax in Humans

   BRIGHT MINDS BIOSCIENCES INC.

   Malaria, Vivax

   phase 1 · mab · completed

   1 trial →

8. Sulopenem

   Iterum Therapeutics plc

   Urinary Tract Infections

   phase 1 · small molecule · terminated

   1 trial →

9. TAF/EVG Vaginal Insert

   United Therapeutics Europe Ltd

   Hiv

   phase 1 · small molecule · completed

   1 trial →

10. TD-1607

    Theravance Biopharma Ireland Umited

    Serious Infections Due to Known or Suspected Gram-positive Pathogens

    phase 1 · small molecule · completed

    1 trial →

11. TD-1607

    Theravance Biopharma Ireland Umited

    Infections

    phase 1 · small molecule · completed

    1 trial →

12. TD-6450

    Theravance Biopharma Ireland Umited

    Hepatitis C

    phase 1 · small molecule · completed

    2 trials →

13. TI-0010

    BRIGHT MINDS BIOSCIENCES INC.

    COVID-19

    phase 1 · mab · active

    1 trial →

14. TKM-100201

    Arbutus Biopharma Corp

    Ebola Virus Infection

    phase 1 · small molecule · terminated

    1 trial →

15. TKM-100802 for Injection

    Arbutus Biopharma Corp

    Ebola Virus Infection

    phase 1 · small molecule · terminated

    1 trial →

16. TNP-2092 capsules

    The First People's Hospital of Lianyungang

    Helicobacter Pylori Infection

    phase 1 · small molecule · completed

    1 trial →

17. TVB-2640 - 50 mg

    Sagimet Biosciences

    Non-alcoholic Steatohepatitis

    phase 1 · small molecule · completed

    1 trial →

18. Telaprevir; Moxifloxacin; Placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 1 · small molecule · completed

    1 trial →

19. Treatment sequence AB

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 1 · small molecule · completed

    1 trial →

20. U10-02-11-001

    PDS Biotechnology Corp

    High-risk HPV Infection and Biopsy-proven CIN1

    phase 1 · mab · completed

    1 trial →

21. UB-421 SC

    United Therapeutics Europe Ltd

    HIV-1-infection

    phase 1 · mab · active

    1 trial →

22. UB-421 SC(dB4C7C22-6 mAb)

    United Therapeutics Europe Ltd

    HIV-1 Infection

    phase 1 · mab · completed

    1 trial →

23. UB-621

    United Therapeutics Europe Ltd

    Herpes Simplex Virus Infection

    phase 1 · small molecule · completed

    1 trial →

24. VCH 916

    Vertex Pharmaceuticals (Australia) Pty.

    HCV Infection

    phase 1 · small molecule · completed

    1 trial →

25. VCH-222

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 1 · small molecule · completed

    1 trial →

26. VGX-3100

    INOVIO PHARMACEUTICALS, INC.

    Papillomavirus Infections

    phase 1 · mab · completed

    1 trial →

27. VGX-6150

    INOVIO PHARMACEUTICALS, INC.

    Hepatitis C, Chronic

    phase 1 · mab · completed

    1 trial →

28. VIR-1111

    Vir Biotechnology

    HIV I Infection

    phase 1 · mab · completed

    1 trial →

29. VIR-3434

    Vir Biotechnology

    Chronic Hepatitis B

    phase 1 · mab · completed

    1 trial →

30. VRON-0200-AdC6

    Vir Biotechnology

    Chronic Hepatitis B

    phase 1 · mab · active

    1 trial →

31. VX-985 or matching placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C

    phase 1 · small molecule · completed

    1 trial →

32. Vaksin Merah Putih - UA SARS-CoV-2 (Vero Cell Inactivated) 5 µg

    Hospital Authority, Hong Kong

    COVID-19 Pandemic

    phase 1 · mab · active

    1 trial →

33. Vebicorvir (VBR)

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 1 · small molecule · completed

    1 trial →

34. Woman-focused intervention

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 1 · other · completed

    1 trial →

35. XTL 6865

    XTL BIOPHARMACEUTICALS LTD

    Hepatitis C

    phase 1 · small molecule · active

    1 trial →

36. XTL-2125

    XTL BIOPHARMACEUTICALS LTD

    Chronic Hepatitis C Virus Infection

    phase 1 · small molecule · terminated

    1 trial →

37. Yinhu Qingwen Granules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Viral Pneumonia

    phase 1 · small molecule · active

    1 trial →

38. ZFN modified T cells

    SANGAMO THERAPEUTICS, INC

    HIV

    phase 1 · mab · completed

    1 trial →

39. intraconazole

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis

    phase 1 · small molecule · completed

    1 trial →

40. routine HIV testing

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 1 · other · completed

    1 trial →

41. sD-NP-GT8 DNA

    INOVIO PHARMACEUTICALS, INC.

    HIV Infections

    phase 1 · mab · completed

    1 trial →

42. shenhuang granule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Sepsis

    phase 1 · small molecule · active

    1 trial →

43. telaprevir formulation A

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C

    phase 1 · small molecule · completed

    1 trial →

44. yimitasvir

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Chronic Hepatitis c

    phase 1 · small molecule · completed

    1 trial →

45. zelicapavir (therapeutic dose)

    ENANTA PHARMACEUTICALS INC

    RSV Infection

    phase 1 · small molecule · completed

    1 trial →

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