Infectious disease · Phase I

Top sponsors

• United Therapeutics Europe 23 programs
• ENANTA PHARMACEUTICALS 14 programs
• Vertex Pharmaceuticals (Australia) 11 programs
• BRIGHT MINDS BIOSCIENCES 10 programs
• Chinese Academy of 10 programs
• ASSEMBLY BIOSCIENCES 9 programs
• Aligos Therapeutics 8 programs
• Anaxis Pharma 8 programs
• Sunshine Guojian Pharmaceutical 8 programs
• INOVIO Pharmaceuticals 7 programs
• MSD Merck Sharp 6 programs
• Sinovac Research and 6 programs

1. Administration of the malaria inoculum

   CNS Pharmaceuticals

   Malaria

   phase 1 · mab · completed

   1 trial →

2. Alirocumab

   Regeneron UK Limited

   Sepsis

   phase 1 · small molecule · completed

   1 trial →

3. Antibody UB-421

   United Therapeutics Europe Ltd

   HIV-1 Infection in Adults (Asymptomatic)

   phase 1 · small molecule · completed

   1 trial →

4. Artesunate (Test)

   Pfizer

   Falciparum Malaria

   phase 1 · small molecule · completed

   1 trial →

5. Azithromycin Pill

   Arrowhead Pharmaceuticals Ireland Limited

   Infections

   phase 1 · small molecule · active

   1 trial →

6. B/F/TAF

   Gilead Sciences Ireland UC

   HIV-1-infection

   phase 1 · small molecule · completed

   1 trial →

7. BAL2420-CP-101

   Lacuna Pharma Pty Ltd

   Severe infections caused by Gram-negative bacteria

   phase 1 · other · active

   1 trial →

8. BCX4430

   Biocryst

   Filovirus Infections

   phase 1 · small molecule · completed

   1 trial →

9. BGB DXP593

   BeiGene

   Covid19

   phase 1 · small molecule · completed

   1 trial →

10. BNT351-01

    BioNTech SE

    HIV-1 infection

    phase 1 · other · active

    1 trial →

11. BS-02

    Blue Earth Diagnostics Ireland Ltd

    Treatment of human papilloma virus (HPV) associated infections, precancers and cancers

    phase 1 · other · active

    1 trial →

12. BS-03

    Blue Earth Diagnostics Ireland Ltd

    Treatment of human papilloma virus (HPV) associated infections and cancers

    phase 1 · other · active

    1 trial →

13. Bempegaldesleukin

    Nektar Therapeutics UK Limited

    Covid-19

    phase 1 · small molecule · completed

    1 trial →

14. CD19/CD20 Dual-Target in vivo CAR-T Lentiviral product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory B-cell Malignancies

    phase 1 · mab · active

    1 trial →

15. CINE963A02103

    Novartis Pharmaceuticals

    Malaria

    phase 1 · other · active

    1 trial →

16. CLARI-21-24

    Lacuna Pharma Pty Ltd

    Infectious diseases

    phase 1 · other · active

    1 trial →

17. CLBS119

    LISATA THERAPEUTICS, INC.

    Covid-19

    phase 1 · mab · terminated

    1 trial →

18. CM-101

    Chemomab Therapeutics

    Nonalcoholic Steatohepatitis (NASH)

    phase 1 · small molecule · completed

    1 trial →

19. CMV-TCR-T cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    CMV Infection or Reactivation After Allogenic HSCT

    phase 1 · mab · completed

    1 trial →

20. COVID-HIG

    United Therapeutics Europe Ltd

    SARS-CoV-2 Infection

    phase 1 · mab · completed

    1 trial →

21. COVID-HIGIV

    United Therapeutics Europe Ltd

    COVID-19

    phase 1 · mab · completed

    1 trial →

22. CPA 556-24

    s.r.o.

    healthy subjects, It is used in conditions with decreased immunity to enhance it e.g. in case of recurrent and chronic viral infections.

    phase 1 · other · active

    1 trial →

23. CPI-006

    Corvus Pharmaceuticals

    COVID-19

    phase 1 · small molecule · completed

    1 trial →

24. CRV431

    Hepion Pharmaceuticals

    Hepatitis B

    phase 1 · small molecule · completed

    1 trial →

25. CSL760

    CSL Behring GmbH

    Coronavirus Disease 2019 (COVID-19)

    phase 1 · mab · terminated

    1 trial →

26. CTX-187-101

    Centauri Biotech SL

    Bacterial Infection

    phase 1 · other · active

    1 trial →

27. CX842B2111

    Lacuna Pharma Pty Ltd

    Helicobacter pylori infection, GERD

    phase 1 · other · active

    1 trial →

28. Campylobacter jejuni strain CG8421

    United Therapeutics Europe Ltd

    Campylobacter Infections

    phase 1 · mab · active

    1 trial →

29. Casirivimab and Imdevimab Antibody Cocktail

    Regeneron UK Limited

    COVID-19

    phase 1 · small molecule · terminated

    1 trial →

30. Ceftobiprole OATP1B interaction study

    Lacuna Pharma Pty Ltd

    Community-acquired bacterial pneumonia

    phase 1 · other · active

    1 trial →

31. Chloroquine

    GlaxoSmithKline

    Malaria

    phase 1 · small molecule · completed

    1 trial →

32. Coadministration of GA2 Sporozoites With Adjuvants (CoGA)

    Disc Medicine

    Falciparum malaria

    phase 1 · other · active

    1 trial →

33. D/ChAd63-CA

    United Therapeutics Europe Ltd

    Malaria

    phase 1 · mab · completed

    1 trial →

34. DEB025

    ENANTA PHARMACEUTICALS INC

    Hepatitis C Virus

    phase 1 · small molecule · completed

    1 trial →

35. DF-006-1001

    Wuhan Createrna Science and Technology Co., Ltd

    Chronic Hepatitis B

    phase 1 · other · active

    1 trial →

36. Debio 1453-101

    Alphapharm Pty Ltd

    Sexual Transmitted Infection (STI)

    phase 1 · other · active

    1 trial →

37. Defibrotide

    Jazz Pharmaceuticals Ireland Limited

    COVID

    phase 1 · small molecule · completed

    1 trial →

38. Disulfiram

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 1 · small molecule · completed

    1 trial →

39. Dronabinol Capsules

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 1 · small molecule · active

    1 trial →

40. EDP-235

    ENANTA PHARMACEUTICALS INC

    SARS CoV 2 Infection

    phase 1 · small molecule · completed

    1 trial →

41. EDP-297

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis With Liver Fibrosis

    phase 1 · small molecule · completed

    1 trial →

42. EDP-305

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis

    phase 1 · small molecule · completed

    2 trials →

43. EDP-322

    ENANTA PHARMACEUTICALS INC

    Skin and Soft Tissue Infections

    phase 1 · small molecule · completed

    1 trial →

44. EDP-323

    ENANTA PHARMACEUTICALS INC

    RSV Infection

    phase 1 · small molecule · completed

    3 trials →

45. EDP-494

    ENANTA PHARMACEUTICALS INC

    Hepatitis C

    phase 1 · small molecule · completed

    1 trial →

46. EDP-514

    ENANTA PHARMACEUTICALS INC

    Hepatitis B

    phase 1 · small molecule · completed

    1 trial →

47. EDP-514

    ENANTA PHARMACEUTICALS INC

    Chronic HBV Infection

    phase 1 · small molecule · completed

    2 trials →

48. EDP-721

    ENANTA PHARMACEUTICALS INC

    Chronic Hepatitis B Virus Infection

    phase 1 · small molecule · terminated

    1 trial →

Frequently asked questions