Friday, July 10, 2026

Intelligence · Clinical pipeline

Neurology & CNS R&D Pipeline

Alzheimer's, Parkinson's, epilepsy, MS, and CNS pipeline assets tracked by phase and sponsor.

Programs 675

Quick answer

Neurology & CNS: NovaPharmaNews indexes 675 neurology & cns clinical pipeline programs from ClinicalTrials.gov with phase, modality, NCT identifiers, and sponsor company links. Alzheimer's, Parkinson's, epilepsy, MS, and CNS pipeline assets tracked by phase and sponsor.

Top sponsors

Pipeline programs

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  1. Characterization of Immune Response in Participants from a Posdinemab Study

    Janssen-Cilag International N.V.

    Early Alzheimer's disease

    phase 1 other active

    1 trial
  2. Citalopram

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Depression

    phase 1 small molecule active

    1 trial
  3. DNL201

    Denali Therapeutics

    Parkinson Disease

    phase 1 small molecule completed

    1 trial
  4. DNL628

    Denali Therapeutics

    Alzheimer Disease, Early Onset

    phase 1 small molecule active

    1 trial
  5. DNL747

    Denali Therapeutics

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial
  6. DNLI-K-0001

    Denali Therapeutics

    Early Alzheimer's Disease

    phase 1 other active

    1 trial
  7. Divalproex Sodium Extended-release 250mg

    BRIGHT MINDS BIOSCIENCES INC.

    Epilepsy

    phase 1 small molecule active

    1 trial
  8. Donepezil Dihydroxynaphthalate for Injection

    Shanghai University of Traditional Chinese Medicine

    Alzheimer Disease

    phase 1 small molecule active

    1 trial
  9. Dose dense re-challenge of high dose methotre...

    Pari Pharma GmbH

    Oncology: RELAPSED PRIMARY CNS LYMPHOMA

    phase 1 other active

    1 trial
  10. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 1 small molecule completed

    1 trial
  11. ENA-001

    BRIGHT MINDS BIOSCIENCES INC.

    Respiratory Depression

    phase 1 small molecule active

    1 trial
  12. Effect of NBI-921355 on corticospinal excitability in healthy participants

    NEUROCRINE BIOSCIENCES INC

    Epilepsy

    phase 1 other active

    1 trial
  13. First-in-Human Study of RO7812653

    Hoffmann-La Roche

    Early Symptomatic Alzheimer’s Disease (eAD), (Mild Cognitive Impairment due to AD, or probable AD dementia)

    phase 1 other active

    1 trial
  14. GRoningen Early-PD Ambroxol Treatment Pharmacokinetics

    Disc Medicine

    Parkinson's disease

    phase 1 other active

    1 trial
  15. GT-02287

    Gain Therapeutics

    Parkinson Disease

    phase 1 small molecule active

    1 trial
  16. Glycerol Phenylbutyrate 1100 MG/ML [Ravicti]

    S.L

    STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder

    phase 1 small molecule active

    1 trial
  17. HEC122505MsOH

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Parkinson Disease

    phase 1 small molecule completed

    1 trial
  18. Human Amniotic Epithelial Stem Cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Parkinson's Disease

    phase 1 mab completed

    1 trial
  19. ION269

    IONIS PHARMACEUTICALS INC

    Alzheimer Disease

    phase 1 small molecule terminated

    1 trial
  20. ION269-CS1

    IONIS PHARMACEUTICALS INC

    Alzheimer’s Disease in Individuals with Down Syndrome

    phase 1 other active

    1 trial
  21. IONIS MAPTRx

    IONIS PHARMACEUTICALS INC

    Mild Alzheimer's Disease

    phase 1 small molecule completed

    1 trial
  22. IRX4204

    IO Biotech

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial
  23. ITI-214 Dose A

    Takeda

    Schizophrenia

    phase 1 small molecule terminated

    1 trial
  24. Infudopa i.v.

    Lxo Ireland Designated Activity Company

    Parkinson Disease

    phase 1 small molecule completed

    1 trial
  25. Ixazomib (NINLARO®) capsules / Matching placebo capsules

    Takeda

    Relapsing Remitting Multiple Sclerosis

    phase 1 small molecule active

    1 trial
  26. Jiedu Tongluo granules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Post-stroke Depression

    phase 1 small molecule completed

    1 trial
  27. KHK6640

    KYOWA KIRIN AUSTRALIA PTY LTD

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial
  28. KIH24001

    The George Institute

    Alzheimer´s disease

    phase 1 other active

    1 trial
  29. KYV-101 (Biological) - 0.33 ×10^8 cells

    Kyverna Therapeutics

    Progressive Multiple Sclerosis

    phase 1 mab active

    1 trial
  30. KYV-101 anti-CD19 CAR-T cell therapy

    Kyverna Therapeutics

    Multiple Sclerosis

    phase 1 mab active

    1 trial
  31. Ketamine

    United Therapeutics Europe Ltd

    Acute Depression

    phase 1 small molecule terminated

    1 trial
  32. LAMOT-04-24

    Lacuna Pharma Pty Ltd

    Bipolar disorder, Epilepsy

    phase 1 other active

    1 trial
  33. LBT-3627

    Biotech Pharmaceutical Co.,

    Parkinson Disease

    phase 1 small molecule active

    1 trial
  34. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Multiple Sclerosis (MS)

    phase 1 mab active

    1 trial
  35. LX1001

    Lexeo Therapeutics

    Alzheimer Disease

    phase 1 mab active

    1 trial
  36. LY03010/CT-EUR-102

    Lacuna Pharma Pty Ltd

    Schizophrenia

    phase 1 other active

    1 trial
  37. LY4006896

    Eli Lilly and Company

    Parkinson Disease

    phase 1 small molecule active

    1 trial
  38. Levodopa

    Blackmores Limited

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial
  39. Levodopa Cyclops®

    BRIGHT MINDS BIOSCIENCES INC.

    Parkinson

    phase 1 other completed

    1 trial
  40. Lu AF28996

    H. Lundbeck A/S

    Parkinson Disease

    phase 1 small molecule active

    1 trial
  41. Lu AF28996 in Patients With Parkinson's Disease

    H. Lundbeck A/S

    Parkinson's Disease

    phase 1 other active

    1 trial
  42. MEDI1341

    Takeda

    Parkinson's Disease

    phase 1 small molecule completed

    2 trials
  43. MP-101-02

    Lacuna Pharma Pty Ltd

    Amyotrophic Lateral Sclerosis (ALS), Alzheimer’s Disease (AD)

    phase 1 other active

    1 trial
  44. MRx0029

    4D Molecular Therapeutics

    Idiopathic Parkinson Disease

    phase 1 mab terminated

    1 trial
  45. Motivational Interviewing

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 1 other completed

    1 trial
  46. N-acetylcysteine

    Ultragenyx UK Limited

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial
  47. NBI-1117570-1769

    NEUROCRINE BIOSCIENCES INC

    Neurological and neuropsychiatric conditions

    phase 1 other active

    1 trial
  48. NDX-1017

    BRIGHT MINDS BIOSCIENCES INC.

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many neurology & cns pipeline programs are tracked?

675 programs match this therapeutic area based on indication text, program name, and registry metadata.

Where does pipeline data come from?

ClinicalTrials.gov records linked to NovaPharmaNews company profiles. Verify on ClinicalTrials.gov before investment decisions.