Autoimmune & immunology · Phase III

Top sponsors

• Takeda 39 programs
• Janssen-Cilag International N.V 26 programs
• Anaxis Pharma 20 programs
• AbbVie 18 programs
• Novartis India 17 programs
• AbbVie Deutschland GmbH 13 programs
• HOFFMANN-LA ROCHE 11 programs
• Eli Lilly and 9 programs
• Chinese Academy of 8 programs
• Bristol-Myers Squibb Australia 7 programs
• PARItec 7 programs
• Pacira Ireland 7 programs

1. Placebo

   AbbVie

   Rheumatoid Arthritis

   phase 3 · small molecule · completed

   1 trial →

2. Placebo for Adalimumab

   AbbVie

   Rheumatoid Arthritis

   phase 3 · small molecule · active

   1 trial →

3. Placebo for risankizumab, ABBV-066

   AbbVie Deutschland GmbH & Co. KG

   Crohn's disease

   phase 3 · small molecule · active

   1 trial →

4. Placebo injections

   Centocor B.V.

   Rheumatoid Arthritis

   phase 3 · small molecule · completed

   1 trial →

5. Placebo to Descartes-08, Descartes-08

   Cartesian Therapeutics

   generalized myasthenia gravis

   phase 3 · small molecule · active

   1 trial →

6. Placebo to MK-7240 (Tulisokibart), tulisokibart

   Merck Sharp and Dohme

   Crohn’s Disease or Ulcerative Colitis

   phase 3 · small molecule · active

   1 trial →

7. Placebo to Upadacitinib

   AbbVie

   Rheumatoid Arthritis

   phase 3 · small molecule · completed

   1 trial →

8. Platelet Rich Plasma Injection

   United Therapeutics Europe Ltd

   Osteoarthritis of the Shoulder

   phase 3 · mab · completed

   1 trial →

9. Ponesimod

   Vanda Pharmaceuticals Netherlands B.V.

   Moderate-to-severe Chronic Plaque Psoriasis

   phase 3 · small molecule · active

   1 trial →

10. Pozelimab + Cemdisiran

    Regeneron UK Limited

    Generalized Myasthenia Gravis

    phase 3 · small molecule · active

    1 trial →

11. RA101495-02.302

    Lacuna Pharma Pty Ltd

    Generalized Myasthenia Gravis

    phase 3 · small molecule · active

    1 trial →

12. RC18G006

    Vor Biopharma

    Generalized Myasthenia Gravis

    phase 3 · small molecule · active

    1 trial →

13. REFINE_2020

    Fondazione Telethon ETS

    Generalized Myasthenia Gravis

    phase 3 · small molecule · active

    1 trial →

14. REGN475

    Regeneron UK Limited

    Osteoarthritis, Knee

    phase 3 · small molecule · completed

    1 trial →

15. RHB-104

    RedHill Biopharma

    Crohn's Disease

    phase 3 · small molecule · completed

    1 trial →

16. RHB-104-04

    RedHill Biopharma

    Crohn Disease

    phase 3 · small molecule · completed

    1 trial →

17. RO7790121 Placebo, RO7790121

    Hoffmann-La Roche

    Moderately to Severely Active Crohn's Disease (CD)

    phase 3 · small molecule · active

    1 trial →

18. RO7790121, RO7790121 Placebo

    Hoffmann-La Roche

    Moderately to Severely Active Crohn's Disease (CD)

    phase 3 · small molecule · active

    1 trial →

19. RO7790121, RO7790121 Placebo

    Hoffmann-La Roche

    Moderately to Severely Active Ulcerative Colitis (UC)

    phase 3 · small molecule · active

    1 trial →

20. RPC01-3203

    Celgene Europe Limited

    Moderately to Severely Active Crohn's Disease

    phase 3 · small molecule · active

    1 trial →

21. RTX-GRT7039, Naropin® 5 mg/ml Injektionslösung

    Gruenenthal GmbH

    Moderate to severe pain associated with Osteoarthritis of the knee

    phase 3 · small molecule · active

    1 trial →

22. Rifaximin

    The First People's Hospital of Lianyungang

    Crohn Disease

    phase 3 · small molecule · active

    1 trial →

23. Risankizumab

    AbbVie

    Psoriasis

    phase 3 · small molecule · active

    1 trial →

24. Rituximab

    Lxo Ireland Designated Activity Company

    Lupus Nephritis

    phase 3 · mab · terminated

    1 trial →

25. Rituximab

    The First People's Hospital of Lianyungang

    Refractory Myasthenia Gravis

    phase 3 · small molecule · active

    1 trial →

26. Roflumilast 0.3% cream

    Arcutis Biotherapeutics

    Chronic Plaque Psoriasis

    phase 3 · small molecule · completed

    1 trial →

27. Roflumilast Foam 0.3%

    Arcutis Biotherapeutics

    Scalp Psoriasis

    phase 3 · small molecule · completed

    1 trial →

28. SAR153191 (REGN88)

    Regeneron UK Limited

    Rheumatoid Arthritis

    phase 3 · small molecule · completed

    2 trials →

29. SECUKINUMAB

    Novartis Pharmaceuticals

    Polymyalgia Rheumatica

    phase 3 · small molecule · active

    1 trial →

30. SL0044

    Lacuna Pharma Pty Ltd

    Systemic lupus erythematosus (SLE)

    phase 3 · small molecule · active

    1 trial →

31. SL0046

    Lacuna Pharma Pty Ltd

    Systemic lupus erythematosus (SLE)

    phase 3 · small molecule · active

    1 trial →

32. SMART-JIA

    The George Institute

    Juvenile Idiopathic Arthritis

    phase 3 · small molecule · active

    1 trial →

33. SMC021 Oral Calcitonin

    Nordic Bioscience A/S

    Osteoarthritis

    phase 3 · small molecule · completed

    1 trial →

34. SPD476

    Takeda

    Ulcerative Colitis

    phase 3 · small molecule · completed

    1 trial →

35. SPD476 (mesalazine)

    Takeda

    Colitis, Ulcerative

    phase 3 · small molecule · completed

    1 trial →

36. SPD476-302

    Takeda

    Ulcerative Colitis

    phase 3 · small molecule · completed

    1 trial →

37. Sarilumab

    Sanofi Pasteur

    Rheumatoid Arthritis

    phase 3 · small molecule · terminated

    1 trial →

38. Sarilumab SAR153191 (REGN88)

    Regeneron UK Limited

    Polymyalgia Rheumatica

    phase 3 · small molecule · terminated

    1 trial →

39. Satralizumab

    Hoffmann-La Roche

    NMDAR Autoimmune Encephalitis

    phase 3 · small molecule · active

    1 trial →

40. Secukinumab

    Novartis Pharmaceuticals

    Psoriatic Arthritis

    phase 3 · small molecule · completed

    2 trials →

41. Secukinumab

    Novartis Pharmaceuticals

    Plaque Psoriasis

    phase 3 · small molecule · completed

    1 trial →

42. Secukinumab (75 mg)

    Novartis Pharmaceuticals

    Psoriatic Arthritis

    phase 3 · small molecule · completed

    1 trial →

43. Sirolimus

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lupus Nephritis

    phase 3 · small molecule · active

    1 trial →

44. Sonelokimab

    MoonLake Immunotherapeutics

    psoriatic arthritis (PsA)

    phase 3 · small molecule · active

    1 trial →

45. Sonelokimab

    MoonLake Immunotherapeutics

    Arthritis, Psoriatic

    phase 3 · small molecule · active

    4 trials →

46. Standard of Care Treatment

    Kyverna Therapeutics

    Myasthenia Gravis

    phase 3 · small molecule · active

    1 trial →

47. TAK-279

    Takeda

    Plaque Psoriasis

    phase 3 · small molecule · active

    3 trials →

48. TAK-279

    Takeda

    Generalized Pustular Psoriasis

    phase 3 · small molecule · active

    1 trial →

Frequently asked questions