Autoimmune & immunology · Phase III

Top sponsors

• Takeda 39 programs
• Janssen-Cilag International N.V 26 programs
• Anaxis Pharma 20 programs
• AbbVie 18 programs
• Novartis India 17 programs
• AbbVie Deutschland GmbH 13 programs
• HOFFMANN-LA ROCHE 11 programs
• Eli Lilly and 9 programs
• Chinese Academy of 8 programs
• Bristol-Myers Squibb Australia 7 programs
• PARItec 7 programs
• Pacira Ireland 7 programs

1. MB04-C-01-23

   Mabxience Research SL

   Rheumatoid Arthritis

   phase 3 · small molecule · active

   1 trial →

2. MG0014

   Lacuna Pharma Pty Ltd

   Generalized Myasthenia Gravis

   phase 3 · small molecule · active

   1 trial →

3. MG0015

   Lacuna Pharma Pty Ltd

   Generalized Myasthenia Gravis

   phase 3 · small molecule · active

   1 trial →

4. MICROPREP III

   ISTA Pharma Limited

   knee osteoarthritis

   phase 3 · other · active

   1 trial →

5. MINJUVI 200 mg powder for concentrate for solution for infusion

   Incyte

   Immune-mediated thrombocytopenia, Autoimmune thrombocytopenia, Autoimmune hemolytic anemia

   phase 3 · small molecule · active

   1 trial →

6. MK-6194, Placebo for MK-6194

   Merck Sharp and Dohme

   Systemic Lupus Erythematosus

   phase 3 · small molecule · active

   1 trial →

7. MK-7240-001

   Merck Sharp and Dohme

   Ulcerative colitis

   phase 3 · small molecule · active

   1 trial →

8. MK-7240-008

   Merck Sharp and Dohme

   Crohn’s Disease

   phase 3 · small molecule · active

   1 trial →

9. MK-7240-008 study 2

   Merck Sharp and Dohme

   Crohn’s Disease

   phase 3 · small molecule · active

   1 trial →

10. MLN0002-3024

    Takeda

    Moderately to severely active Ulcerative Colitis (UC)

    phase 3 · small molecule · active

    1 trial →

11. MLN0002-3025

    Takeda

    Moderately to severely active Crohn's disease (CD)

    phase 3 · small molecule · active

    1 trial →

12. MLN0002-3029

    Takeda

    Active Ulcerative Colitis (UC) or Crohn's disease (CD)

    phase 3 · small molecule · active

    1 trial →

13. MMX Mesalamine/Mesalazine (Low Dose)

    Takeda

    Ulcerative Colitis

    phase 3 · small molecule · completed

    1 trial →

14. MOM-M281-006

    Janssen-Cilag International N.V.

    Warm Autoimmune Hemolytic Anemia

    phase 3 · small molecule · active

    1 trial →

15. MS700568_0183

    Merck Sharp and Dohme

    Generalized Myasthenia Gravis

    phase 3 · small molecule · active

    1 trial →

16. MT-5547

    Tanabe Pharma

    Osteoarthritis, Knee / Osteoarthritis, Hip

    phase 3 · small molecule · completed

    1 trial →

17. Matching Placebo for Piclidenoson, Piclidenoson

    Can-Fite BioPharma

    Plaque psoriasis

    phase 3 · small molecule · active

    1 trial →

18. Matching Placebo for TAK-279, ZASOCITINIB

    Takeda

    Plaque Psoriasis

    phase 3 · small molecule · active

    1 trial →

19. Matching Placebo for Upadacitinib

    AbbVie

    Crohn's Disease

    phase 3 · small molecule · completed

    1 trial →

20. Medi-546

    AstraZeneca

    Systemic Lupus Erythematosus

    phase 3 · small molecule · active

    1 trial →

21. Mirikizumab

    Eli Lilly and Company

    Ulcerative Colitis

    phase 3 · small molecule · active

    2 trials →

22. Mirikizumab SC

    Eli Lilly and Company

    Ulcerative Colitis

    phase 3 · small molecule · completed

    1 trial →

23. Mirikizumab, Mirikizumab

    Eli Lilly Co.

    Ulcerative Colitis

    phase 3 · small molecule · active

    1 trial →

24. NGAM-16

    Maze Therapeutics

    Prevention of a Major infection in patients with Hypogammaglobulinemia and Autoimmune or Rheumatic Conditions receiving treatment with B-cell depletion therapy.

    phase 3 · small molecule · active

    1 trial →

25. NI-501; emapalumab, NI-501; emapalumab

    Swedish Orphan Biovitrum Pty Ltd

    Macrophage activation syndrome (MAS) in the context of Systemic Juvenile Idiopathic Arthritis (sJIA) and Adult onset Still's disease (AOSD). MAS in the context of pediatric and adult Systemic Lupus Erythematosus (SLE).

    phase 3 · small molecule · active

    1 trial →

26. NN9490-8026

    NovoThirteen

    Overweight or obesity, and knee osteoarthritis

    phase 3 · small molecule · active

    1 trial →

27. NN9490-8294

    NovoThirteen

    Overweight or obesity, and knee osteoarthritis

    phase 3 · small molecule · active

    1 trial →

28. Obexelimab

    Zenas BioPharma

    Warm Autoimmune Hemolytic Anemia

    phase 3 · small molecule · active

    1 trial →

29. Olokizumab

    International Peace Maternity and Child Health Hospital

    Rheumatoid Arthritis

    phase 3 · small molecule · completed

    1 trial →

30. Olokizumab 64 mg SC q4w

    International Peace Maternity and Child Health Hospital

    Rheumatoid Arthritis

    phase 3 · small molecule · completed

    1 trial →

31. Olokizumab 64mg q4w

    International Peace Maternity and Child Health Hospital

    Rheumatoid Arthritis

    phase 3 · small molecule · completed

    1 trial →

32. Ontamalimab

    Takeda

    Crohn's Disease

    phase 3 · mab · terminated

    3 trials →

33. Ontamalimab

    Shire

    Crohn's Disease

    phase 3 · small molecule · terminated

    1 trial →

34. Ontamalimab

    Takeda

    Ulcerative Colitis

    phase 3 · small molecule · terminated

    3 trials →

35. Ozanimod, Ozanimod

    Celgene Europe Limited

    Ulcerative colitis

    phase 3 · small molecule · active

    1 trial →

36. Ozanimod, Ozanimod

    Celgene Europe Limited

    Moderately to Severely Active Crohn's Disease

    phase 3 · small molecule · active

    1 trial →

37. P160931J

    Pari Pharma GmbH

    Adult patients with ulcerative colitis diagnosed for at least 3 months

    phase 3 · small molecule · active

    1 trial →

38. PA0016

    Lacuna Pharma Pty Ltd

    Psoriatic arthritis

    phase 3 · small molecule · active

    1 trial →

39. PB_A&A-ASC-FISTULA_1

    COLLEGIUM PHARMACEUTICAL, INC

    Anal or recto-cutaneous or recto-vaginal Crohn-related fistula

    phase 3 · other · active

    1 trial →

40. PF-06438179

    Pfizer

    Rheumatoid Arthritis

    phase 3 · mab · completed

    1 trial →

41. PGET

    Atrium Therapeutics

    Osteoarthritis

    phase 3 · other · terminated

    1 trial →

42. PS0021

    Lacuna Pharma Pty Ltd

    Moderate to Severe Plaque Psoriasis

    phase 3 · small molecule · active

    1 trial →

43. Paeoniflorin + phosphatidylcholine or silymarin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatitis, Autoimmune

    phase 3 · small molecule · terminated

    1 trial →

44. Peficitinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rheumatoid Arthritis (RA)

    phase 3 · small molecule · completed

    1 trial →

45. Placebo

    AbbVie

    Ulcerative Colitis (UC)

    phase 3 · small molecule · completed

    2 trials →

46. Placebo

    Sanofi Pasteur

    Osteoarthritis

    phase 3 · small molecule · completed

    1 trial →

47. Placebo

    Pfizer

    Ulcerative Colitis

    phase 3 · small molecule · completed

    1 trial →

48. Placebo

    AbbVie

    Psoriatic Arthritis

    phase 3 · mab · active

    1 trial →

Frequently asked questions