Wednesday, July 8, 2026

Patent intelligence · US

US 12221422

Compounds and their use for the treatment of alpha1-antitrypsin deficiency

granted A61KA61K31/513A61K9/0053A61P
Status granted
Linked drugs 1
Pipeline programs 6
Years to expiry 19
Applicant portfolio 7
Patent details — US 12221422

Quick answer

US 12221422 (Compounds and their use for the treatment of alpha1-antitrypsin deficiency) is held by CENTESSA PHARMACEUTICALS (UK) LIMITED. Status: granted. Granted Feb 11, 2025. Expires Feb 6, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Key facts

Grant date
Expiration
Claims
10
CPC classes
A61K, A61K31/513, A61K9/0053, A61P, A61P1/16, A61P11/06

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Frequently asked questions

What is US patent 12221422?

US 12221422 (Compounds and their use for the treatment of alpha1-antitrypsin deficiency) is held by CENTESSA PHARMACEUTICALS (UK) LIMITED. Status: granted. Granted Feb 11, 2025. Expires Feb 6, 2045 (19 years remaining) — relevant for patent-cliff and LOE planning.

Who owns US 12221422?

CENTESSA PHARMACEUTICALS (UK) LIMITED is listed as the applicant in USPTO PatentsView records indexed by NovaPharmaNews. We track 7 pharmaceutical patents for this assignee.

When does US 12221422 expire?

Our index shows an expiration date of Feb 6, 2045 (19 years from today). Confirm material dates against USPTO, FDA Orange Book, or qualified counsel before contractual decisions.